117 research outputs found

    The Ledger and Times, April 13, 1973

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    Determinants of Safety Device Use in Adults Age 18-22 Years.

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    Background: The determinants of safety device use and non-use, in 18-22 year olds, are not clear and were targeted in this research. The literature revealed that safety devices are used due to personal safety, habit and legal reasons. Safety devices are not used due to physical discomfort, only drive/ride short distances and forgetfulness. Methods: This study is a multivariable, quantitative-non-experimental study, conducted on the campus of Augsburg College during an orientation event in June 2003. A multiple choice written questionnaire was distributed to participants of the orientation event. The identification of trends and patterns were determined to establish the determinants of safety device use. Results: Of 180 questionnaires 171 were returned for analysis. Of the 171,167 were valid (N: 167). Of the respondents 41.3% were male and 58.7% were female. All of the respondents were 18-22 years old. The most frequently used mode of daily transportation was a motor vehicle (85.5%). Reasons for using safety belts included personal safety , habit and legal reasons . Reasons for safety belt non-use were physical discomfort and only drive short distances . Conclusions: This study revealed that young adults use safety belts the most frequently, followed by motorcycle helmet use and bicycle helmets were used the least frequently. In each of the three categories personal safety , legal requirements and habit were the leading reasons for using safety devices. In addition, of the three categories physical discomfort and only drive short distances were the leading reasons for safety device non-use

    A workbook to improve accurate and critical listening in the junior high school.

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    Thesis (Ed.M.)--Boston Universit

    The Murray Ledger and Times, July 17, 1993

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    Energy in a Finite World: Paths to a Sustainable Future (Volume 1)

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    This volume summarizes the results of a seven-year study conducted at the International Institute for Applied Systems Analysis (IIASA) in Laxenburg, Austria. The work, which involved over 140 scientists from 20 countries, aimed to provide new and critical insights into the international long-term dimensions of the energy problem. Given this objective, the 50-year period from 1980 to 2030 was analyzed in detail, though parts of the study looked even further into the future. Geographically, all countries of the world were included -- developed and developing, market and centrally planned economies. The picture that emerges is one of a world facing, during the 1980-2030 period, what is anticipated to be the steepest ever increase in its population. At the same time, the developing regions of the world, in which most of this population growth will occur, will be trying to close the economic gap separating them from the developed regions. Despite the resultant strains on the world's physical resources, on its institutions, and on human ingenuity, the conclusion is that the physical resources and the human potential exist to provide the energy for a 2030 world that is more prosperous than the world of today while supporting a population double that of 1975. Moreover, if resources are developed judiciously and strategically, the world of 2030 could be at the threshold of a critical and ultimately necessary transition from a global energy system based on depletable fossil fuels to one based on nondepletable, sustainable resources. The companion volume, "Energy in a Finite World, Vol. 2, A Global Systems Analysis", also published by Ballinger, presents the study findings in detail, with the references and qualifications typical of a comprehensive scientific work. ER-81-4, "Energy in a Finite World: Executive Summary", by Alan McDonald, provides a concise summary of the study and is available from IIASA

    The Trinity Tatler, Spring 1955

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    Contents: Martial Law By John P. Redmond 1 The Professor\u27s Pedals By E. P. Townsend 2Money-Mad-Milkman By Richard Condon 5Trinity\u27s Naval Battery By Richard Freytag 7June Graduates Must Still Reckon With Uncle Sam By L. F. Page III 8God\u27s File Cabinets By Donald F. Burr 10SCCAT By Ward s. Just 12 The Battle of March 17, 1911 By Burton s. Price 13 A Winter\u27s Visit to Cape Cod By W. E. Learnard 14Last Time With the Boys By D. W. Penfield 15Sure Cure for a History Hangover By E. P. Townsend 17 The Definition of A Word By D. F. Mountford 18https://digitalrepository.trincoll.edu/tatler/1001/thumbnail.jp

    The Murray Ledger and Times, July 3, 1993

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    DECODING LYMPHOCYTE DEVELOPMENT AND DIFFERENTIATION

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    Mammals are equipped with a complex adaptive immune system that provides them protection against foreign pathogens, toxins or allergenic agents and also tumors. B and T lymphocytes comprise critical building blocks of this system and are essential in establishing effective humoral and cellular immune responses. In this thesis, we first introduced the reader to key processes involved at multiple stages of lymphocyte development and differentiation. In the next part, we demonstrated that transition from Pro- to Pre-B cells stage during early development of B lymphocytes is exclusively dependent on the Ig heavy chain (IgHC) and not directed by a non-coding function of the Ig heavy mRNA (IgHR). We also highlighted the capacity of progenitor B cells in sensing very low amounts of IgHC, that licenses further development. Phenotypically and functionally, lymphocytes display great heterogeneity and plasticity. This cellular plasticity is accounted for by dynamic changes in their epigenetic landscape including post translational modifications of histone. Across distinct developmental and differentiation stages, the genome of a lymphocyte undergoes many of these epigenetic modifications. In subsequent sections of the thesis, we highlighted the functional significance of an epigenetic writer, DOT1L in lymphocytes biology. We demonstrated that DOT1L plays a critical role in establishing germinal center B cells, a B cell differentiation state that is closely associated with lymphoma formation. Furthermore, we showed that DOT1L prevents premature differentiation of B cells into plasma-like cells. In later part of the thesis, we provided a detailed characterization of CD8+ T lymphocytes that lack DOT1L. We demonstrated that DOT1L is a key epigenetic writer that safeguards the epigenetic identity of naïve CD8+ T lymphocytes. In absence of DOT1L, CD8+ T lymphocytes prematurely differentiate towards antigen-independent memory T cells. Apart from physiological significance, lymphocytes especially B cells also represent as a unique biological system that have programmed DNA double strand break (DSBs). These DSBs provide the basis of key processes that are related with their functionality. With their capacity of regulating DSBs repair, B cells can be used to study the role of proteins that may become involved in DSBs repair process. In next part of the thesis, with the aim to check the proposed direct role of poorly characterized protein CAAP1 in regulating apoptosis and delaying DNA double strand break (DSBs) repair, we described a new mouse model that lack CAAP1. Comprehensive analysis involving different cellular systems including B lymphocytes that lack CAAP1 we disproved the proposed role of CAAP1 and suggested that new approaches should be adopted to unravel significance of CAAP1 in biological system. At the end, we summarized and discussed key findings from the thesis and also presents an outlook for the future research
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