1,244,412 research outputs found

    Play Selection in the Department of Speech and Drama at Pan American University in the 1970s and 1980s: Twenty Years of Excluding Latino Plays

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    The theatre program at the University of Texas-Pan American has a long history of excluding Latino plays from its production seasons, even though the university is located near the Mexican border and the majority of its students are Mexican American. The regional population served by this publicly-funded school, which has been state-funded since 1965, is predominantly Mexican American and Spanish speaking. Furthermore, as reflected in its name, the school’s mission has included for more than half a century a commitment to advance the “blending” of the North American and Latin American cultures. This article reviews the school’s production record over a twenty-year period, from 1970 to 1990, when more than one hundred and fifty full-length plays were produced by its theatre program, not one of which was about Mexican Americans or Mexico. Selected background information is provided to help illuminate the historical context in which the school’s theatre faculty decided year after year to exclude Latino plays from their theatre on the Mexican border

    Amino acid metabolism conflicts with protein diversity

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    The twenty protein coding amino acids are found in proteomes with different relative abundances. The most abundant amino acid, leucine, is nearly an order of magnitude more prevalent than the least abundant amino acid, cysteine. Amino acid metabolic costs differ similarly, constraining their incorporation into proteins. On the other hand, sequence diversity is necessary for protein folding, function and evolution. Here we present a simple model for a cost-diversity trade-off postulating that natural proteomes minimize amino acid metabolic flux while maximizing sequence entropy. The model explains the relative abundances of amino acids across a diverse set of proteomes. We found that the data is remarkably well explained when the cost function accounts for amino acid chemical decay. More than one hundred proteomes reach comparable solutions to the trade-off by different combinations of cost and diversity. Quantifying the interplay between proteome size and entropy shows that proteomes can get optimally large and diverse

    Adapt or perish? How parties respond to party system saturation in 21 Western democracies, 1945–2011

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    This study examines whether (and how) parties adapt to party system saturation (PSS). A party system is oversaturated when a higher effective number of parties contests elections than predicted. Previous research has shown that parties are more likely to exit when party systems are oversaturated. This article examines whether parties will adapt by increasing the nicheness of their policy platform, by forming electoral alliances or by merging. Based on time-series analyses of 522 parties contesting 357 elections in twenty-one established Western democracies between 1945 and 2011, the study finds that parties are more likely to enter – and less likely to leave – electoral alliances if PSS increases. Additionally, a small share of older parties will merge. The results highlight parties’ limited capacity to adapt to their environments, which has important implications for the literature on party (system) change and models of electoral competition

    Overview of the blood transfusion policy in preterms on the Neonatal Intensive Care Unit

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    Preterm infants on the Neonatal Intensive Care Unit receive a greater number of red cell transfusions than any other hospitalised group. Over the past twenty years research has focused on setting standards to determine when it is necessary to transfuse packed cells in this cohort, whilst exploring the use of red cell growth factors and other substrates judiciously in order to reduce and/or avoid red cell transfusions and limit donor exposure. One hundred and eighty-one blood transfusions were administered to 106 preterms less than 35 weeks gestation on the NICU during 2009 in Malta. The median (range) volume of blood used from each bag supplied by the Blood Transfusion Department was 25.8mls (10-50mls), the rest of which was discarded. Risk factors for transfusion included Extremely Low Birth Weight (less than 1kg) and a gestation of less than 30 weeks. The blood transfusion guidelines presently in use on the local NICU were reviewed and compared with more restrictive guidelines on other units and suggestions made to reduce transfusions in line with these guidelines. A reduction in transfusion aliquots provided for neonates to just 50mls from the customary 250mls in a dedicated single-donor programme will safeguard limited health resources and minimise donor exposure.peer-reviewe
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