4,126 research outputs found

    Slick and lumpy : heavy cream

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    A conversation with myself. A look inside my mind, process, and feelings. Slick and Lumpy. Creamy, oozing, leaking, dripping. Poured, molded, and sewn. Not a body, but my body, big and bursting and spilling out. Two things placed next to each other and observed. Lots of dessert, frosting, squishing, covering. A conversation with a painting, with a building technique. Fetish and healing, leather, vinyl, latex. Private and public space. Identity, imposter syndrome, digital fabrication. Combining and subtracting and stuffing. Is it appealing, sexy, charming, or revolting, ugly and gross

    The MESSy aerosol submodel MADE3 (v2.0b): description and a box model test

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    We introduce MADE3 (Modal Aerosol Dynamics model for Europe, adapted for global applications, 3rd generation; version: MADE3v2.0b), an aerosol dynamics submodel for application within the MESSy framework (Modular Earth Submodel System). MADE3 builds on the predecessor aerosol submodels MADE and MADE-in. Its main new features are the explicit representation of coarse mode particle interactions both with other particles and with condensable gases, and the inclusion of hydrochloric acid (HCl) / chloride (Cl) partitioning between the gas and condensed phases. The aerosol size distribution is represented in the new submodel as a superposition of nine lognormal modes: one for fully soluble particles, one for insoluble particles, and one for mixed particles in each of three size ranges (Aitken, accumulation, and coarse mode size ranges). <br><br> In order to assess the performance of MADE3 we compare it to its predecessor MADE and to the much more detailed particle-resolved aerosol model PartMC-MOSAIC in a box model simulation of an idealised marine boundary layer test case. MADE3 and MADE results are very similar, except in the coarse mode, where the aerosol is dominated by sea spray particles. Cl is reduced in MADE3 with respect to MADE due to the HCl / Cl partitioning that leads to Cl removal from the sea spray aerosol in our test case. Additionally, the aerosol nitrate concentration is higher in MADE3 due to the condensation of nitric acid on coarse mode particles. MADE3 and PartMC-MOSAIC show substantial differences in the fine particle size distributions (sizes &lesssim; 2 μm) that could be relevant when simulating climate effects on a global scale. Nevertheless, the agreement between MADE3 and PartMC-MOSAIC is very good when it comes to coarse particle size distributions (sizes &gtrsim; 2 μm), and also in terms of aerosol composition. Considering these results and the well-established ability of MADE in reproducing observed aerosol loadings and composition, MADE3 seems suitable for application within a global model

    Carbon and nitrogen flux through the Cape rock lobster jasus lalandii (H. Milne Edwards), with particular reference to the nearshore Benguela system

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    Bibliography: leaves 169-198.Observations and experiments on Jasus lalandii were undertaken over the period 1977 to 1986 to quantify the passage of carbon and nitrogen through populations at Oudekraal and Robben Island on the west coast of South Africa. The terms of the energy flow equation, C=P+R+G+UE+Ux+Uo+F (where C=consumption, P=production, R=respiration, G=reproduction, UE=Exuvial loss, Ux=excretion of exogenous nitrogen, Up =excretion of endogenous nitrogen and F=faeces), were quantified by combining field data and laboratory results. With this information the role played by J. lalandii in the kelp-bed ecosystem under the influence of the Benguela current was explored and quantified

    Distribution of hydrogen peroxide over Europe during the BLUESKY aircraft campaign

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    In this work we present airborne in situ trace gas observations of hydrogen peroxide (H2_2O2_2) and the sum of organic hydroperoxides over Europe during the Chemistry of the Atmosphere – Field Experiments in Europe (CAFE-EU, also known as BLUESKY) aircraft campaign using a wet chemical monitoring system, the HYdrogen Peroxide and Higher Organic Peroxide (HYPHOP) monitor. The campaign took place in May–June 2020 over central and southern Europe with two additional flights dedicated to the North Atlantic flight corridor. Airborne measurements were performed on the High Altitude and LOng-range (HALO) research operating out of Oberpfaffenhofen (southern Germany). We report average mixing ratios for H2_2O2_2 of 0.32 ± 0.25, 0.39 ± 0.23 and 0.38 ± 0.21 ppbv in the upper and middle troposphere and the boundary layer over Europe, respectively. Vertical profiles of measured H2_2O2_2 reveal a significant decrease, in particular above the boundary layer, contrary to previous observations, most likely due to cloud scavenging and subsequent rainout of soluble species. In general, the expected inverted C-shaped vertical trend with maximum hydrogen peroxide mixing ratios at 3–7 km was not found during BLUESKY. This deviates from observations during previous airborne studies over Europe, i.e., 1.64 ± 0.83 ppbv_v during the HOOVER campaign and 1.67 ± 0.97 ppbv during UTOPIHAN-ACT II/III. Simulations with the global chemistry–transport model EMAC partly reproduce the strong effect of rainout loss on the vertical profile of H2_2O2_2. A sensitivity study without H2_2O2_2 scavenging performed using EMAC confirms the strong influence of clouds and precipitation scavenging on hydrogen peroxide concentrations. Differences between model simulations and observations are most likely due to difficulties in the simulation of wet scavenging processes due to the limited model resolution

    julF2005

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    From July 2005 Robert Kelly Archive

    Clinical and behavioural features of SYNGAP1-related intellectual disability: a parent and caregiver description

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    BACKGROUND: SYNGAP1-related intellectual disability (ID) is a recently described neurodevelopmental disorder that is caused by pathogenic variation in the SYNGAP1 gene. To date, the behavioural characteristics of this disorder have mainly been highlighted via the prevalence of existing diagnoses in case series. We set out to detail the behavioural features of this disorder by undertaking interviews with those who have a child with SYNGAP1-related ID to allow them to describe their child’s behaviour. METHODS: We conducted 27 semi-structured interviews with parents and caregivers which covered basic information (e.g., age, gender), family history, perinatal history, past medical history, developmental history, epilepsy, behavioural history, and a general description of their child’s behaviour. RESULTS: Using a mixed quantitative and qualitative approach, the responses from the parents indicated that those with SYNGAP1-related ID showed high rates of autism spectrum disorder (52%), difficulties with fine and gross motor skills, delays in language development, and a high prevalence of epilepsy (70%). A qualitative analysis highlighted their general behaviour affected the themes of daily living skills, distress-related behaviours, emotional regulation, difficulties with change, a lack of danger awareness, and sensory differences. Sensory features described involved auditory, visual, tactile, gustatory, and proprioceptive themes. CONCLUSIONS: Our findings and behavioural descriptions provide important insights as well as implications for the diagnosis and care of those with SYNGAP1-related ID. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s11689-022-09437-x
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