The cardiac bidomain model and homogenization

We provide a rather simple proof of a homogenization result for the bidomain model of cardiac electrophysiology. Departing from a microscopic cellular model, we apply the theory of two-scale convergence to derive the bidomain model. To allow for some relevant nonlinear membrane models, we make essential use of the boundary unfolding operator. There are several complications preventing the application of standard homogenization results, including the degenerate temporal structure of the bidomain equations and a nonlinear dynamic boundary condition on an oscillating surface.Comment: To appear in Networks and Heterogeneous Media, Special Issue on Mathematical Methods for Systems Biolog

On an exponential attractor for a class of PDEs with degenerate diffusion and chemotaxis

In this article we deal with a class of strongly coupled parabolic systems that encompasses two different effects: degenerate diffusion and chemotaxis. Such classes of equations arise in the mesoscale level modeling of biomass spreading mechanisms via chemotaxis. We show the existence of an exponential attractor and, hence, of a finite-dimensional global attractor under certain 'balance conditions' on the order of the degeneracy and the growth of the chemotactic function

A quasilinear differential inclusion for viscous and rate-independent damage systems in non-smooth domains

This paper focuses on rate-independent damage in elastic bodies. Since the driving energy is nonconvex, solutions may have jumps as a function of time, and in this situation it is known that the classical concept of energetic solutions for rate-independent systems may fail to accurately describe the behavior of the system at jumps. Therefore we resort to the (by now well-established) vanishing viscosity approach to rate-independent modeling, and approximate the model by its viscous regularization. In fact, the analysis of the latter PDE system presents remarkable difficulties, due to its highly nonlinear character. We tackle it by combining a variational approach to a class of abstract doubly nonlinear evolution equations, with careful regularity estimates tailored to this specific system, relying on a q-Laplacian type gradient regularization of the damage variable. Hence for the viscous problem we conclude the existence of weak solutions, satisfying a suitable energy-dissipation inequality that is the starting point for the vanishing viscosity analysis. The latter leads to the notion of (weak) parameterized solution to our rate-independent system, which encompasses the influence of viscosity in the description of the jump regime

On the viscous Cahn-Hilliard equation with singular potential and inertial term

We consider a relaxation of the viscous Cahn-Hilliard equation induced by the second-order inertial term~$u_{tt}$. The equation also contains a semilinear term $f(u)$ of "singular" type. Namely, the function $f$ is defined only on a bounded interval of ${\mathbb R}$ corresponding to the physically admissible values of the unknown $u$, and diverges as $u$ approaches the extrema of that interval. In view of its interaction with the inertial term $u_{tt}$, the term $f(u)$ is difficult to be treated mathematically. Based on an approach originally devised for the strongly damped wave equation, we propose a suitable concept of weak solution based on duality methods and prove an existence result.Comment: 11 page

Complete damage in linear elastic materials - Modeling, weak formulation and existence results

In this work, we introduce a degenerating PDE system with a time-depending domain for complete damage processes under time-varying Dirichlet boundary conditions. The evolution of the system is described by a doubly nonlinear differential inclusion for the damage process and a quasi-static balance equation for the displacement field which are strongly nonlinearly coupled. In our proposed model, the material may completely disintegrate which is indispensable for a realistic modeling of damage processes in elastic materials. Complete damage theories lead to several mathematical problems since for instance coercivity properties of the free energy are lost and, therefore, several difficulties arise. For the introduced complete damage model, we propose a classical formulation and a corresponding suitable weak formulation in an $SBV$-framework. The main aim is to prove existence of weak solutions for the introduced degenerating model. In addition, we show that the classical differential inclusion can be regained from the notion of weak solutions under certain regularity assumptions which is a novelty in the theory of complete damage models of this type