74 research outputs found

    Semi-automated search for abnormalities in mammographic X-ray images

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    Breast cancer is the most commonly diagnosed cancer among Canadian women; x-ray mammography is the leading screening technique for early detection. This work introduces a semi-automated technique for analyzing mammographic x-ray images to measure their degree of suspiciousness for containing abnormalities. The designed system applies the discrete wavelet transform to parse the images and extracts statistical features that characterize an image’s content, such as the mean intensity and the skewness of the intensity. A naïve Bayesian classifier uses these features to classify the images, achieving sensitivities as high as 99.5% for a data set containing 1714 images. To generate confidence levels, multiple classifiers are combined in three possible ways: a sequential series of classifiers, a vote-taking scheme of classifiers, and a network of classifiers tuned to detect particular types of abnormalities. The third method offers sensitivities of 99.85% or higher with specificities above 60%, making it an ideal candidate for pre-screening images. Two confidence level measures are developed: first, a real confidence level measures the true probability that an image was suspicious; and second, a normalized confidence level assumes that normal and suspicious images were equally likely to occur. The second confidence measure allows for more flexibility and could be combined with other factors, such as patient age and family history, to give a better true confidence level than assuming a uniform incidence rate. The system achieves sensitivities exceeding those in other current approaches while maintaining reasonable specificity, especially for the sequential series of classifiers and for the network of tuned classifiers

    Mammography

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    In this volume, the topics are constructed from a variety of contents: the bases of mammography systems, optimization of screening mammography with reference to evidence-based research, new technologies of image acquisition and its surrounding systems, and case reports with reference to up-to-date multimodality images of breast cancer. Mammography has been lagged in the transition to digital imaging systems because of the necessity of high resolution for diagnosis. However, in the past ten years, technical improvement has resolved the difficulties and boosted new diagnostic systems. We hope that the reader will learn the essentials of mammography and will be forward-looking for the new technologies. We want to express our sincere gratitude and appreciation?to all the co-authors who have contributed their work to this volume

    Implementation of medical imaging with telemedicine for the early detection and diagnoses of breast cancer to women in remote areas

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    Nowadays, the cancer topic has become a global concern. Furthermore, breast cancer persists to be the top leading cause of death to women population and the second cause of cancer death after the lung cancer globally. Various technologies and techniques have been searched, developed and studied over the years to detect the disease at the early stage; the early diagnosis saves many lives in both developed and developing countries. The detection of cancer through a screening process before its symptoms emerge increases the survival rate dramatically (Li, Meaney and Paulsen). Moreover, sufficient knowledge of the disease, qualified staff, accurate, appropriate treatment and diagnosis contribute to the successful cure of the disease; however, the cancer treatment is not affordable by many and sometimes not available to the very needy, and more precisely in developing countries. In this research, we aimed to explore the early detection of breast cancer using the new image compression algorithm: DYNAMAC, a compression tool that finds its basis in nonlinear dynamical systems theory; we implemented this algorithm through the D-transform, a digital sequence used to compress the digital media (Wang and Huang) & (Antoine, Murenzi and Vandergheynst). The goal is to use this method to analyze the average profile of diseased and healthy breast images obtained from a digital mammography to detect diseased tissues. After the detection of cancerous tumors, we worked to establish a remote care to women victims of breast cancer using the Telecommunication infrastructure through primarily Teleradiology and the Next Generation Internet (NGI) technology. Over the methods and techniques previously used in the area of medical imaging techniques, DYNAMAC algorithm is the most easily implemented along with its features that include cost saving in addition to best meeting the requirements of the breast imaging technology

    Caracterización de Patrones Anormales en Mamografías

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    Abstract. Computer-guided image interpretation is an extensive research area whose main purpose is to provide tools to support decision-making, for which a large number of automatic techniques have been proposed, such as, feature extraction, pattern recognition, image processing, machine learning, among others. In breast cancer, the results obtained at this area, they have led to the development of diagnostic support systems, which have even been approved by the FDA (Federal Drug Administration). However, the use of those systems is not widely extended in clinic scenarios, mainly because their performance is unstable and poorly reproducible. This is due to the high variability of the abnormal patterns associated with this neoplasia. This thesis addresses the main problem associated with the characterization and interpretation of breast masses and architectural distortion, mammographic findings directly related to the presence of breast cancer with higher variability in their form, size and location. This document introduces the design, implementation and evaluation of strategies to characterize abnormal patterns and to improve the mammographic interpretation during the diagnosis process. The herein proposed strategies allow to characterize visual patterns of these lesions and the relationship between them to infer their clinical significance according to BI-RADS (Breast Imaging Reporting and Data System), a radiologic tool used for mammographic evaluation and reporting. The obtained results outperform some obtained by methods reported in the literature both tasks classification and interpretation of masses and architectural distortion, respectively, demonstrating the effectiveness and versatility of the proposed strategies.Resumen. La interpretación de imágenes guiada por computador es una área extensa de investigación cuyo objetivo principal es proporcionar herramientas para el soporte a la toma de decisiones, para lo cual se han usado un gran número de técnicas de extracción de características, reconocimiento de patrones, procesamiento de imágenes, aprendizaje de máquina, entre otras. En el cáncer de mama, los resultados obtenidos en esta área han dado lugar al desarrollo de sistemas de apoyo al diagnóstico que han sido incluso aprobados por la FDA (Federal Drug Administration). Sin embargo, el uso de estos sistemas no es ampliamente extendido, debido principalmente, a que su desempeño resulta inestable y poco reproducible frente a la alta variabilidad de los patrones anormales asociados a esta neoplasia. Esta tesis trata el principal problema asociado a la caracterización y análisis de masas y distorsión de la arquitectura debido a que son hallazgos directamente relacionados con la presencia de cáncer y que usualmente presentan mayor variabilidad en su forma, tamaño y localización, lo que altera los resultados diagnósticos. Este documento introduce el diseño, implementación y evaluación de un conjunto de estrategias para caracterizar patrones anormales relacionados con este tipo de hallazgos para mejorar la interpretación y soportar el diagnóstico mediante la imagen mamaria. Los modelos aquí propuestos permiten caracterizar patrones visuales y la relación entre estos para inferir su significado clínico según el estándar BI-RADS (Breast Imaging Reporting and Data System) usado para la evaluación y reporte mamográfico. Los resultados obtenidos han demostrado mejorar a los resultados obtenidos por los métodos reportados en la literatura en tareas como clasificación e interpretación de masas y distorsión arquitectural, demostrando la efectividad y versatilidad de las estrategia propuestas.Doctorad

    Visibility recovery on images acquired in attenuating media. Application to underwater, fog, and mammographic imaging

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    136 p.When acquired in attenuating media, digital images of ten suffer from a particularly complex degradation that reduces their visual quality, hindering their suitability for further computational applications, or simply decreasing the visual pleasan tness for the user. In these cases, mathematical image processing reveals it self as an ideal tool to recover some of the information lost during the degradation process. In this dissertation,we deal with three of such practical scenarios in which this problematic is specially relevant, namely, underwater image enhancement, fogremoval and mammographic image processing. In the case of digital mammograms,X-ray beams traverse human tissue, and electronic detectorscapture them as they reach the other side. However, the superposition on a bidimensional image of three-dimensional structures produces low contraste dimages in which structures of interest suffer from a diminished visibility, obstructing diagnosis tasks. Regarding fog removal, the loss of contrast is produced by the atmospheric conditions, and white colour takes over the scene uniformly as distance increases, also reducing visibility.For underwater images, there is an added difficulty, since colour is not lost uniformly; instead, red colours decay the fastest, and green and blue colours typically dominate the acquired images. To address all these challenges,in this dissertation we develop new methodologies that rely on: a)physical models of the observed degradation, and b) the calculus of variations.Equipped with this powerful machinery, we design novel theoreticaland computational tools, including image-dependent functional energies that capture the particularities of each degradation model. These energie sare composed of different integral terms that are simultaneous lyminimized by means of efficient numerical schemes, producing a clean,visually-pleasant and use ful output image, with better contrast and increased visibility. In every considered application, we provide comprehensive qualitative (visual) and quantitative experimental results to validateour methods, confirming that the developed techniques out perform other existing approaches in the literature

    Visibility Recovery on Images Acquired in Attenuating Media. Application to Underwater, Fog, and Mammographic Imaging

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    When acquired in attenuating media, digital images often suffer from a particularly complex degradation that reduces their visual quality, hindering their suitability for further computational applications, or simply decreasing the visual pleasantness for the user. In these cases, mathematical image processing reveals itself as an ideal tool to recover some of the information lost during the degradation process. In this dissertation, we deal with three of such practical scenarios in which this problematic is specially relevant, namely, underwater image enhancement, fog removal and mammographic image processing. In the case of digital mammograms, X-ray beams traverse human tissue, and electronic detectors capture them as they reach the other side. However, the superposition on a bidimensional image of three-dimensional structures produces lowcontrasted images in which structures of interest suffer from a diminished visibility, obstructing diagnosis tasks. Regarding fog removal, the loss of contrast is produced by the atmospheric conditions, and white colour takes over the scene uniformly as distance increases, also reducing visibility. For underwater images, there is an added difficulty, since colour is not lost uniformly; instead, red colours decay the fastest, and green and blue colours typically dominate the acquired images. To address all these challenges, in this dissertation we develop new methodologies that rely on: a) physical models of the observed degradation, and b) the calculus of variations. Equipped with this powerful machinery, we design novel theoretical and computational tools, including image-dependent functional energies that capture the particularities of each degradation model. These energies are composed of different integral terms that are simultaneously minimized by means of efficient numerical schemes, producing a clean, visually-pleasant and useful output image, with better contrast and increased visibility. In every considered application, we provide comprehensive qualitative (visual) and quantitative experimental results to validate our methods, confirming that the developed techniques outperform other existing approaches in the literature

    Digital Image Processing Applications

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    Digital image processing can refer to a wide variety of techniques, concepts, and applications of different types of processing for different purposes. This book provides examples of digital image processing applications and presents recent research on processing concepts and techniques. Chapters cover such topics as image processing in medical physics, binarization, video processing, and more
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