ECG-Based Arrhythmia Classification using Recurrent Neural Networks in Embedded Systems

Cardiac arrhythmia is one of the most important cardiovascular diseases (CVDs), causing million deaths every year. Moreover it is difficult to diagnose because it occurs intermittently and as such requires the analysis of large amount of data, collected during the daily life of patients. An important tool for CVD diagnosis is the analysis of electrocardiogram (ECG), because of its non-invasive nature and simplicity of acquisition. In this work we propose a classification algorithm for arrhythmia based on recurrent neural networks (RNNs) that operate directly on ECG data, exploring the effectiveness and efficiency of several variations of the general RNN, in particular using different types of layers implementing the network memory. We use the MIT-BIH arrhythmia database and the evaluation protocol recommended by the Association for the Advancement of Medical Instrumentation (AAMI). After designing and testing the effectiveness of the different networks, we then test its porting to an embedded platform, namely the STM32 microcontroller architecture from ST, using a specific framework to port a pre-built RNN to the embedded hardware, convert it to optimized code for the platform and evaluate its performance in terms of resource usage. Both in binary and multiclass classification, the basic RNN model outperforms the other architectures in terms of memory storage (∼117 KB), number of parameters (∼5 k) and inference time (∼150 ms), while the RNN LSTM-based achieved the best accuracy (∼90%)

Real-time human ambulation, activity, and physiological monitoring:taxonomy of issues, techniques, applications, challenges and limitations

Automated methods of real-time, unobtrusive, human ambulation, activity, and wellness monitoring and data analysis using various algorithmic techniques have been subjects of intense research. The general aim is to devise effective means of addressing the demands of assisted living, rehabilitation, and clinical observation and assessment through sensor-based monitoring. The research studies have resulted in a large amount of literature. This paper presents a holistic articulation of the research studies and offers comprehensive insights along four main axes: distribution of existing studies; monitoring device framework and sensor types; data collection, processing and analysis; and applications, limitations and challenges. The aim is to present a systematic and most complete study of literature in the area in order to identify research gaps and prioritize future research directions

Portable decision support for diagnosis of traumatic brain injury

Early detection and diagnosis of Traumatic Brain Injury (TBI) could reduce significantly the death rate and improve the quality of life of the people affected if emergency services are equipped with tools for TBI diagnosis at the place of the accident. This problem is addressed here by proposing a portable decision support system called EmerEEG, which is based on Quantitative Electroencephalography (qEEG). The contributions of the paper are the proposed system concept, architecture and decision support for TBI diagnosis. By the virtue of its easily operable mobile system, the proposed solution for emergency TBI diagnosis provides valuable decision support at a very early stage after an accident, thereby enabling a short response time in critical situations and better prospects for the people affected

AUTOMATED ARTIFACT REMOVAL AND DETECTION OF MILD COGNITIVE IMPAIRMENT FROM SINGLE CHANNEL ELECTROENCEPHALOGRAPHY SIGNALS FOR REAL-TIME IMPLEMENTATIONS ON WEARABLES

Electroencephalogram (EEG) is a technique for recording asynchronous activation of neuronal firing inside the brain with non-invasive scalp electrodes. EEG signal is well studied to evaluate the cognitive state, detect brain diseases such as epilepsy, dementia, coma, autism spectral disorder (ASD), etc. In this dissertation, the EEG signal is studied for the early detection of the Mild Cognitive Impairment (MCI). MCI is the preliminary stage of Dementia that may ultimately lead to Alzheimers disease (AD) in the elderly people. Our goal is to develop a minimalistic MCI detection system that could be integrated to the wearable sensors. This contribution has three major aspects: 1) cleaning the EEG signal, 2) detecting MCI, and 3) predicting the severity of the MCI using the data obtained from a single-channel EEG electrode. Artifacts such as eye blink activities can corrupt the EEG signals. We investigate unsupervised and effective removal of ocular artifact (OA) from single-channel streaming raw EEG data. Wavelet transform (WT) decomposition technique was systematically evaluated for effectiveness of OA removal for a single-channel EEG system. Discrete Wavelet Transform (DWT) and Stationary Wavelet Transform (SWT), is studied with four WT basis functions: haar, coif3, sym3, and bior4.4. The performance of the artifact removal algorithm was evaluated by the correlation coefficients (CC), mutual information (MI), signal to artifact ratio (SAR), normalized mean square error (NMSE), and time-frequency analysis. It is demonstrated that WT can be an effective tool for unsupervised OA removal from single channel EEG data for real-time applications.For the MCI detection from the clean EEG data, we collected the scalp EEG data, while the subjects were stimulated with five auditory speech signals. We extracted 590 features from the Event-Related Potential (ERP) of the collected EEG signals, which included time and spectral domain characteristics of the response. The top 25 features, ranked by the random forest method, were used for classification models to identify subjects with MCI. Robustness of our model was tested using leave-one-out cross-validation while training the classifiers. Best results (leave-one-out cross-validation accuracy 87.9%, sensitivity 84.8%, specificity 95%, and F score 85%) were obtained using support vector machine (SVM) method with Radial Basis Kernel (RBF) (sigma = 10, cost = 102). Similar performances were also observed with logistic regression (LR), further validating the results. Our results suggest that single-channel EEG could provide a robust biomarker for early detection of MCI. We also developed a single channel Electro-encephalography (EEG) based MCI severity monitoring algorithm by generating the Montreal Cognitive Assessment (MoCA) scores from the features extracted from EEG. We performed multi-trial and single-trail analysis for the algorithm development of the MCI severity monitoring. We studied Multivariate Regression (MR), Ensemble Regression (ER), Support Vector Regression (SVR), and Ridge Regression (RR) for multi-trial and deep neural regression for the single-trial analysis. In the case of multi-trial, the best result was obtained from the ER. In our single-trial analysis, we constructed the time-frequency image from each trial and feed it to the convolutional deep neural network (CNN). Performance of the regression models was evaluated by the RMSE and the residual analysis. We obtained the best accuracy with the deep neural regression method

A Survey Study of the Current Challenges and Opportunities of Deploying the ECG Biometric Authentication Method in IoT and 5G Environments

The environment prototype of the Internet of Things (IoT) has opened the horizon for researchers to utilize such environments in deploying useful new techniques and methods in different fields and areas. The deployment process takes place when numerous IoT devices are utilized in the implementation phase for new techniques and methods. With the wide use of IoT devices in our daily lives in many fields, personal identification is becoming increasingly important for our society. This survey aims to demonstrate various aspects related to the implementation of biometric authentication in healthcare monitoring systems based on acquiring vital ECG signals via designated wearable devices that are compatible with 5G technology. The nature of ECG signals and current ongoing research related to ECG authentication are investigated in this survey along with the factors that may affect the signal acquisition process. In addition, the survey addresses the psycho-physiological factors that pose a challenge to the usage of ECG signals as a biometric trait in biometric authentication systems along with other challenges that must be addressed and resolved in any future related research.