Sustainable Development Goals learning from Mount Hakusan Biosphere Reserve

Kanazawa University International Student Cente

Cloud-based genomics pipelines for ophthalmology: Reviewed from research to clinical practice

Aim: To familiarize clinicians with clinical genomics, and to describe the potential of cloud computing for enabling the future routine use of genomics in eye hospital settings. Design: Review article exploring the potential for cloud-based genomic pipelines in eye hospitals. Methods: Narrative review of the literature relevant to clinical genomics and cloud computing, using PubMed and Google Scholar. A broad overview of these fields is provided, followed by key examples of their integration. Results: Cloud computing could benefit clinical genomics due to scalability of resources, potentially lower costs, and ease of data sharing between multiple institutions. Challenges include complex pricing of services, costs from mistakes or experimentation, data security, and privacy concerns. Conclusions and future perspectives: Clinical genomics is likely to become more routinely used in clinical practice. Currently this is delivered in highly specialist centers. In the future, cloud computing could enable delivery of clinical genomics services in non-specialist hospital settings, in a fast, cost-effective way, whilst enhancing collaboration between clinical and research teams

New Hampshire University Research and Industry Plan: A Roadmap for Collaboration and Innovation

This University Research and Industry plan for New Hampshire is focused on accelerating innovation-led development in the state by partnering academia’s strengths with the state’s substantial base of existing and emerging advanced industries. These advanced industries are defined by their deep investment and connections to research and development and the high-quality jobs they generate across production, new product development and administrative positions involving skills in science, technology, engineering and math (STEM)

WabiSabi: Centrally Coordinated CoinJoins with Variable Amounts

Bitcoin transfers value on a public ledger of transactions anyone can verify. Coin ownership is defined in terms of public keys. Despite potential use for private transfers, research has shown that users’ activity can often be traced in practice. Businesses have been built on dragnet surveillance of Bitcoin users because of this lack of strong privacy, which harms its fungibility, a basic property of functional money. Although the public nature of this design lacks strong guarantees for privacy, it does not rule it out. A number of methods have been proposed to strengthen privacy. Among these is CoinJoin, an approach based on multiparty transactions that can introduce ambiguity and break common assumptions that underlie heuristics used for deanonymization. Existing implementations of CoinJoin have several limitations which may partly explain the lack of their widespread adoption. This work introduces WabiSabi, a new protocol for centrally coordinated CoinJoin implementations utilizing keyed verification anonymous credentials and homomorphic value commitments. This improves earlier approaches which utilize blind signatures in both privacy and flexibility, enabling novel use cases and reduced overhead

C-EMO: A Modeling Framework for Collaborative Network Emotions

Recent research in the area of collaborative networks is focusing on the social and organizational complexity of collaboration environments as a way to prevent technological failures and consequently contribute for the collaborative network’s sustainability. One direction is moving towards the need to provide “human-tech” friendly systems with cognitive models of human factors such as stress, emotion, trust, leadership, expertise or decision-making ability. In this context, an emotion-based system is being proposed with this thesis in order to bring another approach to avoid collaboration network’s failures and help in the management of conflicts. This approach, which is expected to improve the performance of existing CNs, adopts some of the models developed in the human psychology, sociology and affective computing areas. The underlying idea is to “borrow” the concept of human-emotion and apply it into the context of CNs, giving the CN players the ability to “feel emotions”. Therefore, this thesis contributes with a modeling framework that conceptualizes the notion of “emotion” in CNs and a methodology approach based on system dynamics and agent-based techniques that estimates the CN player’s “emotional states” giving support to decision-making processes. Aiming at demonstrating the appropriateness of the proposed framework a simulation prototype was implemented and a validation approach was proposed consisting of simulation of scenarios, qualitative assessment and validation by research community peers.Recentemente a área de investigação das redes colaborativas tem vindo a debruçar-se na complexidade social e organizacional em ambientes colaborativos e como pode ser usada para prevenir falhas tecnológicas e consequentemente contribuir para redes colaborativas sustentáveis. Uma das direcções de estudo assenta na necessidade de fornecer sistemas amigáveis “humano-tecnológicos” com modelos cognitivos de factores humanos como o stress, emoção, confiança, liderança ou capacidade de tomada de decisão. É neste contexto que esta tese propõe um sistema baseado em emoções com o objectivo de oferecer outra aproximação para a gestão de conflitos e falhas da rede de colaboração. Esta abordagem, que pressupõe melhorar o desempenho das redes existentes, adopta alguns dos modelos desenvolvidos nas áreas da psicologia humana, sociologia e affective computing. A ideia que está subjacente é a de “pedir emprestado” o conceito de emoção humana e aplicá-lo no contexto das redes colaborativas, dando aos seus intervenientes a capacidade de “sentir emoções”. Assim, esta tese contribui com uma framework de modelação que conceptualiza a noção de “emoção” em redes colaborativas e com uma aproximação de metodologia sustentada em sistemas dinâmicos e baseada em agentes que estimam os “estados emocionais” dos participantes e da própria rede colaborativa. De forma a demonstrar o nível de adequabilidade da framework de modelação proposta, foi implementado um protótipo de simulação e foi proposta uma abordagem de validação consistindo em simulação de cenários, avaliação qualitativa e validação pelos pares da comunidade científica

A double-edged sword: Use of computer algebra systems in first-year Engineering Mathematics and Mechanics courses

Many secondary-level mathematics students have experience with graphical calculators from high school. For the purposes of this paper we define graphical calculators as those able to perform rudimentary symbolic manipulation and solve complicated equations requiring very modest user knowledge. The use of more advanced computer algebra systems e.g. Maple, Mathematica, Mathcad, Matlab/MuPad is becoming more prevalent in tertiary-level courses. This paper explores our students’ experience using one such system (MuPad) in first-year tertiary Engineering Mathematics and Mechanics courses. The effectiveness of graphical calculators and computer algebra systems in mathematical pedagogy has been investigated by a multitude of educational researchers (e.g. Ravaglia et al. 1998). Most of these studies found very small or no correlation between student use of graphical calculators or exposure to computer algebra systems with future achievement in mathematics courses (Buteau et al. 2010). In this paper we focus instead on students’ attitude towards a more advanced standalone computer algebra system (MuPad), and whether students’ inclination to use the system is indicative of their mathematical understanding. Paper describing some preliminary research into use of computer algebra systems for teaching engineering mathematics

Data Storage and Dissemination in Pervasive Edge Computing Environments

Nowadays, smart mobile devices generate huge amounts of data in all sorts of gatherings. Much of that data has localized and ephemeral interest, but can be of great use if shared among co-located devices. However, mobile devices often experience poor connectivity, leading to availability issues if application storage and logic are fully delegated to a remote cloud infrastructure. In turn, the edge computing paradigm pushes computations and storage beyond the data center, closer to end-user devices where data is generated and consumed. Hence, enabling the execution of certain components of edge-enabled systems directly and cooperatively on edge devices. This thesis focuses on the design and evaluation of resilient and efficient data storage and dissemination solutions for pervasive edge computing environments, operating with or without access to the network infrastructure. In line with this dichotomy, our goal can be divided into two specific scenarios. The first one is related to the absence of network infrastructure and the provision of a transient data storage and dissemination system for networks of co-located mobile devices. The second one relates with the existence of network infrastructure access and the corresponding edge computing capabilities. First, the thesis presents time-aware reactive storage (TARS), a reactive data storage and dissemination model with intrinsic time-awareness, that exploits synergies between the storage substrate and the publish/subscribe paradigm, and allows queries within a specific time scope. Next, it describes in more detail: i) Thyme, a data storage and dis- semination system for wireless edge environments, implementing TARS; ii) Parsley, a flexible and resilient group-based distributed hash table with preemptive peer relocation and a dynamic data sharding mechanism; and iii) Thyme GardenBed, a framework for data storage and dissemination across multi-region edge networks, that makes use of both device-to-device and edge interactions. The developed solutions present low overheads, while providing adequate response times for interactive usage and low energy consumption, proving to be practical in a variety of situations. They also display good load balancing and fault tolerance properties.Resumo Hoje em dia, os dispositivos móveis inteligentes geram grandes quantidades de dados em todos os tipos de aglomerações de pessoas. Muitos desses dados têm interesse loca- lizado e efêmero, mas podem ser de grande utilidade se partilhados entre dispositivos co-localizados. No entanto, os dispositivos móveis muitas vezes experienciam fraca co- nectividade, levando a problemas de disponibilidade se o armazenamento e a lógica das aplicações forem totalmente delegados numa infraestrutura remota na nuvem. Por sua vez, o paradigma de computação na periferia da rede leva as computações e o armazena- mento para além dos centros de dados, para mais perto dos dispositivos dos utilizadores finais onde os dados são gerados e consumidos. Assim, permitindo a execução de certos componentes de sistemas direta e cooperativamente em dispositivos na periferia da rede. Esta tese foca-se no desenho e avaliação de soluções resilientes e eficientes para arma- zenamento e disseminação de dados em ambientes pervasivos de computação na periferia da rede, operando com ou sem acesso à infraestrutura de rede. Em linha com esta dico- tomia, o nosso objetivo pode ser dividido em dois cenários específicos. O primeiro está relacionado com a ausência de infraestrutura de rede e o fornecimento de um sistema efêmero de armazenamento e disseminação de dados para redes de dispositivos móveis co-localizados. O segundo diz respeito à existência de acesso à infraestrutura de rede e aos recursos de computação na periferia da rede correspondentes. Primeiramente, a tese apresenta armazenamento reativo ciente do tempo (ARCT), um modelo reativo de armazenamento e disseminação de dados com percepção intrínseca do tempo, que explora sinergias entre o substrato de armazenamento e o paradigma pu- blicação/subscrição, e permite consultas num escopo de tempo específico. De seguida, descreve em mais detalhe: i) Thyme, um sistema de armazenamento e disseminação de dados para ambientes sem fios na periferia da rede, que implementa ARCT; ii) Pars- ley, uma tabela de dispersão distribuída flexível e resiliente baseada em grupos, com realocação preventiva de nós e um mecanismo de particionamento dinâmico de dados; e iii) Thyme GardenBed, um sistema para armazenamento e disseminação de dados em redes multi-regionais na periferia da rede, que faz uso de interações entre dispositivos e com a periferia da rede. As soluções desenvolvidas apresentam baixos custos, proporcionando tempos de res- posta adequados para uso interativo e baixo consumo de energia, demonstrando serem práticas nas mais diversas situações. Estas soluções também exibem boas propriedades de balanceamento de carga e tolerância a faltas

Towards Designing Robo-Advisory to Promote Consensus Efficient Group Decision-Making in New Types of Economic Scenarios

Robo-advisors are a new type of FinTech increasingly used by millennials in place of traditional financial advice. Building on artificial intelligence, robo-advisors provide personalized asset and wealth management services. Their application and study have hitherto focused exclusively on individual advisory regarding asset management. We observe a pressing need to investigate robo- advisors’ application for complex artificial intelligence based recommendation tasks both, in context of group decision-making and in contexts beyond asset management, due to robo-advisors’ potential as a lever for integrating artificial intelligence in the entire decision-making process. Thus, we present a action design research in progress aimed at designing such a robo-advisor. More specifically, this study investigates whether and how robo-advisory promotes consensus-efficient group decision-making in new types of economic scenarios (after-sales). Based on a comprehensive problem formulation, we aim towards deriving a set of meta-requirements and design principles that are embodied in a preliminary prototypical instantiation of a robo-advisor

Affective Motivational Collaboration Theory

Existing computational theories of collaboration explain some of the important concepts underlying collaboration, e.g., the collaborators\u27 commitments and communication. However, the underlying processes required to dynamically maintain the elements of the collaboration structure are largely unexplained. Our main insight is that in many collaborative situations acknowledging or ignoring a collaborator\u27s affective state can facilitate or impede the progress of the collaboration. This implies that collaborative agents need to employ affect-related processes that (1) use the collaboration structure to evaluate the status of the collaboration, and (2) influence the collaboration structure when required. This thesis develops a new affect-driven computational framework to achieve these objectives and thus empower agents to be better collaborators. Contributions of this thesis are: (1) Affective Motivational Collaboration (AMC) theory, which incorporates appraisal processes into SharedPlans theory. (2) New computational appraisal algorithms based on collaboration structure. (3) Algorithms such as goal management, that use the output of appraisal to maintain collaboration structures. (4) Implementation of a computational system based on AMC theory. (5) Evaluation of AMC theory via two user studies to a) validate our appraisal algorithms, and b) investigate the overall functionality of our framework within an end-to-end system with a human and a robot