24 research outputs found
An overview of deep learning techniques for epileptic seizures detection and prediction based on neuroimaging modalities: Methods, challenges, and future works
Epilepsy is a disorder of the brain denoted by frequent seizures. The symptoms of seizure include confusion,
abnormal staring, and rapid, sudden, and uncontrollable hand movements. Epileptic seizure detection methods
involve neurological exams, blood tests, neuropsychological tests, and neuroimaging modalities. Among these,
neuroimaging modalities have received considerable attention from specialist physicians. One method to facilitate
the accurate and fast diagnosis of epileptic seizures is to employ computer-aided diagnosis systems (CADS)
based on deep learning (DL) and neuroimaging modalities. This paper has studied a comprehensive overview of
DL methods employed for epileptic seizures detection and prediction using neuroimaging modalities. First, DLbased
CADS for epileptic seizures detection and prediction using neuroimaging modalities are discussed. Also,
descriptions of various datasets, preprocessing algorithms, and DL models which have been used for epileptic
seizures detection and prediction have been included. Then, research on rehabilitation tools has been presented,
which contains brain-computer interface (BCI), cloud computing, internet of things (IoT), hardware implementation
of DL techniques on field-programmable gate array (FPGA), etc. In the discussion section, a comparison
has been carried out between research on epileptic seizure detection and prediction. The challenges in
epileptic seizures detection and prediction using neuroimaging modalities and DL models have been described. In
addition, possible directions for future works in this field, specifically for solving challenges in datasets, DL,
rehabilitation, and hardware models, have been proposed. The final section is dedicated to the conclusion which
summarizes the significant findings of the paper
Promises and pitfalls of deep neural networks in neuroimaging-based psychiatric research
By promising more accurate diagnostics and individual treatment
recommendations, deep neural networks and in particular convolutional neural
networks have advanced to a powerful tool in medical imaging. Here, we first
give an introduction into methodological key concepts and resulting
methodological promises including representation and transfer learning, as well
as modelling domain-specific priors. After reviewing recent applications within
neuroimaging-based psychiatric research, such as the diagnosis of psychiatric
diseases, delineation of disease subtypes, normative modeling, and the
development of neuroimaging biomarkers, we discuss current challenges. This
includes for example the difficulty of training models on small, heterogeneous
and biased data sets, the lack of validity of clinical labels, algorithmic
bias, and the influence of confounding variables
An overview of artificial intelligence techniques for diagnosis of Schizophrenia based on magnetic resonance imaging modalities: Methods, challenges, and future works
Schizophrenia (SZ) is a mental disorder that typically emerges in late adolescence
or early adulthood. It reduces the life expectancy of patients by 15 years.
Abnormal behavior, perception of emotions, social relationships, and reality
perception are among its most significant symptoms. Past studies have revealed
that SZ affects the temporal and anterior lobes of hippocampus regions of the brain. Also, increased volume of cerebrospinal fluid (CSF) and decreased
volume of white and gray matter can be observed due to this disease. Magnetic
resonance imaging (MRI) is the popular neuroimaging technique used to
explore structural/functional brain abnormalities in SZ disorder, owing to its
high spatial resolution. Various artificial intelligence (AI) techniques have been
employed with advanced image/signal processing methods to accurately diagnose
SZ. This paper presents a comprehensive overview of studies conducted on
the automated diagnosis of SZ using MRI modalities. First, an AI-based computer
aided-diagnosis system (CADS) for SZ diagnosis and its relevant sections
are presented. Then, this section introduces the most important conventional
machine learning (ML) and deep learning (DL) techniques in the diagnosis of
diagnosing SZ. A comprehensive comparison is also made between ML and DL
studies in the discussion section. In the following, the most important challenges
in diagnosing SZ are addressed. Future works in diagnosing SZ using AI
techniques and MRI modalities are recommended in another section. Results,
conclusion, and research findings are also presented at the end.Ministerio de Ciencia e Innovación
(España)/ FEDER under the RTI2018-098913-B100 projectConsejerÃa de EconomÃa, Innovación, Ciencia y Empleo (Junta de AndalucÃa) and
FEDER under CV20-45250 and A-TIC-080-UGR18 project
An Overview on Artificial Intelligence Techniques for Diagnosis of Schizophrenia Based on Magnetic Resonance Imaging Modalities: Methods, Challenges, and Future Works
Schizophrenia (SZ) is a mental disorder that typically emerges in late
adolescence or early adulthood. It reduces the life expectancy of patients by
15 years. Abnormal behavior, perception of emotions, social relationships, and
reality perception are among its most significant symptoms. Past studies have
revealed the temporal and anterior lobes of hippocampus regions of brain get
affected by SZ. Also, increased volume of cerebrospinal fluid (CSF) and
decreased volume of white and gray matter can be observed due to this disease.
The magnetic resonance imaging (MRI) is the popular neuroimaging technique used
to explore structural/functional brain abnormalities in SZ disorder owing to
its high spatial resolution. Various artificial intelligence (AI) techniques
have been employed with advanced image/signal processing methods to obtain
accurate diagnosis of SZ. This paper presents a comprehensive overview of
studies conducted on automated diagnosis of SZ using MRI modalities. Main
findings, various challenges, and future works in developing the automated SZ
detection are described in this paper
Machine Learning Methods for Depression Detection Using SMRI and RS-FMRI Images
Major Depression Disorder (MDD) is a common disease throughout the world that negatively influences people’s lives. Early diagnosis of MDD is beneficial, so detecting practical biomarkers would aid clinicians in the diagnosis of MDD. Having an automated method to find biomarkers for MDD is helpful even though it is difficult. The main aim of this research is to generate a method for detecting discriminative features for MDD diagnosis based on Magnetic Resonance Imaging (MRI) data.
In this research, representational similarity analysis provides a framework to compare distributed patterns and obtain the similarity/dissimilarity of brain regions. Regions are obtained by either data-driven or model-driven methods such as cubes and atlases respectively. For structural MRI (sMRI) similarity of voxels of spatial cubes (data-driven) are explored. For resting-state fMRI (rs-fMRI) images, the similarity of the time series of both cubes (data-driven) and atlases (model-driven) are examined. Moreover, the similarity method of the inverse of Minimum Covariant Determinant is applied that excludes outliers from patterns and finds conditionally independent regions given the rest of regions. Next, a statistical test that is robust to outliers, identifies discriminative similarity features between two groups of MDDs and controls. Therefore, the key contribution is the way to get discriminative features that include obtaining similarity of voxel’s cubes/time series using the inverse of robust covariance along with the statistical test. The experimental results show that obtaining these features along with the Bernoulli Naïve Bayes classifier achieves superior performance compared with other methods. The performance of our method is verified by applying it to three imbalanced datasets. Moreover, the similarity-based methods are compared with deep learning and regional-based approaches for detecting MDD using either sMRI or rs-fMRI.
Given that depression is famous to be a connectivity disorder problem, investigating the similarity of the brain’s regions is valuable to understand the behavior of the brain. The combinations of structural and functional brain similarities are explored to investigate the brain’s structural and functional properties together. Moreover, the combination of data-driven (cube) and model-driven (atlas) similarities of rs-fMRI are looked over to evaluate how they affect the performance of the classifier. Besides, discriminative similarities are visualized for both sMRI and rs-fMRI. Also, to measure the informativeness of a cube, the relationship of atlas regions with overlapping cubes and vise versa (cubes with overlapping regions) are explored and visualized. Furthermore, the relationship between brain structure and function has been probed through common similarities between structural and resting-state functional networks