Exploiting Nonlinear Recurrence and Fractal Scaling Properties for Voice Disorder Detection

Background: Voice disorders affect patients profoundly, and acoustic tools can potentially measure voice function objectively. Disordered sustained vowels exhibit wide-ranging phenomena, from nearly periodic to highly complex, aperiodic vibrations, and increased "breathiness". Modelling and surrogate data studies have shown significant nonlinear and non-Gaussian random properties in these sounds. Nonetheless, existing tools are limited to analysing voices displaying near periodicity, and do not account for this inherent biophysical nonlinearity and non-Gaussian randomness, often using linear signal processing methods insensitive to these properties. They do not directly measure the two main biophysical symptoms of disorder: complex nonlinear aperiodicity, and turbulent, aeroacoustic, non-Gaussian randomness. Often these tools cannot be applied to more severe disordered voices, limiting their clinical usefulness.

Methods: This paper introduces two new tools to speech analysis: recurrence and fractal scaling, which overcome the range limitations of existing tools by addressing directly these two symptoms of disorder, together reproducing a "hoarseness" diagram. A simple bootstrapped classifier then uses these two features to distinguish normal from disordered voices.

Results: On a large database of subjects with a wide variety of voice disorders, these new techniques can distinguish normal from disordered cases, using quadratic discriminant analysis, to overall correct classification performance of 91.8% plus or minus 2.0%. The true positive classification performance is 95.4% plus or minus 3.2%, and the true negative performance is 91.5% plus or minus 2.3% (95% confidence). This is shown to outperform all combinations of the most popular classical tools.

Conclusions: Given the very large number of arbitrary parameters and computational complexity of existing techniques, these new techniques are far simpler and yet achieve clinically useful classification performance using only a basic classification technique. They do so by exploiting the inherent nonlinearity and turbulent randomness in disordered voice signals. They are widely applicable to the whole range of disordered voice phenomena by design. These new measures could therefore be used for a variety of practical clinical purposes.
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Characterization of Healthy and Pathological Voice Through Measures Based on Nonlinear Dynamics

In this paper, we propose to quantify the quality of the recorded voice through objective nonlinear measures. Quantification of speech signal quality has been traditionally carried out with linear techniques since the classical model of voice production is a linear approximation. Nevertheless, nonlinear behaviors in the voice production process have been shown. This paper studies the usefulness of six nonlinear chaotic measures based on nonlinear dynamics theory in the discrimination between two levels of voice quality: healthy and pathological. The studied measures are first- and second-order Renyi entropies, the correlation entropy and the correlation dimension. These measures were obtained from the speech signal in the phase-space domain. The values of the first minimum of mutual information function and Shannon entropy were also studied. Two databases were used to assess the usefulness of the measures: a multiquality database composed of four levels of voice quality (healthy voice and three levels of pathological voice); and a commercial database (MEEI Voice Disorders) composed of two levels of voice quality (healthy and pathological voices). A classifier based on standard neural networks was implemented in order to evaluate the measures proposed. Global success rates of 82.47% (multiquality database) and 99.69% (commercial database) were obtained.Publicad

Analysis and Detection of Pathological Voice using Glottal Source Features

Automatic detection of voice pathology enables objective assessment and earlier intervention for the diagnosis. This study provides a systematic analysis of glottal source features and investigates their effectiveness in voice pathology detection. Glottal source features are extracted using glottal flows estimated with the quasi-closed phase (QCP) glottal inverse filtering method, using approximate glottal source signals computed with the zero frequency filtering (ZFF) method, and using acoustic voice signals directly. In addition, we propose to derive mel-frequency cepstral coefficients (MFCCs) from the glottal source waveforms computed by QCP and ZFF to effectively capture the variations in glottal source spectra of pathological voice. Experiments were carried out using two databases, the Hospital Universitario Principe de Asturias (HUPA) database and the Saarbrucken Voice Disorders (SVD) database. Analysis of features revealed that the glottal source contains information that discriminates normal and pathological voice. Pathology detection experiments were carried out using support vector machine (SVM). From the detection experiments it was observed that the performance achieved with the studied glottal source features is comparable or better than that of conventional MFCCs and perceptual linear prediction (PLP) features. The best detection performance was achieved when the glottal source features were combined with the conventional MFCCs and PLP features, which indicates the complementary nature of the features

Improved Algorithm for Pathological and Normal Voices Identification

There are a lot of papers on automatic classification between normal and pathological voices, but they have the lack in the degree of severity estimation of the identified voice disorders. Building a model of pathological and normal voices identification, that can also evaluate the degree of severity of the identified voice disorders among students. In the present work, we present an automatic classifier using acoustical measurements on registered sustained vowels /a/ and pattern recognition tools based on neural networks. The training set was done by classifying students’ recorded voices based on threshold from the literature. We retrieve the pitch, jitter, shimmer and harmonic-to-noise ratio values of the speech utterance /a/, which constitute the input vector of the neural network. The degree of severity is estimated to evaluate how the parameters are far from the standard values based on the percent of normal and pathological values. In this work, the base data used for testing the proposed algorithm of the neural network is formed by healthy and pathological voices from German database of voice disorders. The performance of the proposed algorithm is evaluated in a term of the accuracy (97.9%), sensitivity (1.6%), and specificity (95.1%). The classification rate is 90% for normal class and 95% for pathological class

Detección automática de voz hipernasal de niños con labio y paladar hendido a partir de vocales y palabras del español usando medidas clásicas y análisis no lineal

RESUMEN: Este artículo presenta un sistema para la detección automática de señales de voz hipernasales basado en la combinación de dos diferentes esquemas de caracterización aplicados en las cinco vocales del español y dos palabras seleccionadas. El primer esquema está basado en características clásicas como perturbaciones del periodo fundamental, medidas de ruido y coeficientes cepstrales en la frecuencia de Mel. El segundo enfoque está basado en medidas de dinámica no lineal. Las características más relevantes son seleccionadas usando dos técnicas: análisis de componentes principales y selección flotante hacia adelante secuencial. La decisión acerca de si un registro de voz es hipernasal o sano es tomada usando una máquina de soporte vectorial de margen suave. Los experimentos consideran grabaciones de las cinco vocales del idioma español y las palabras y se consideran, asimismo, tres conjuntos de características: (1) el enfoque clásico, (2) el análisis de dinámica no lineal y (3) la combinación de ambos esquemas. En general, los aciertos son mayores y más estables cuando las características clásicas y no lineales son combinadas, indicando que el análisis de dinámica no lineal se complementa con el esquema clásico.ABSTRACT: This paper presents a system for the automatic detection of hypernasal speech signals based on the combination of two different characterization approaches applied to the five spanish vowels and two selected words. The first approach is based on classical features such as pitch period perturbations, noise measures, and Mel-Frequency Cepstral Coefficients (MFCC). The second approach is based on the Non-Linear Dynamics (NLD) analysis. The most relevant features are selected and sorted using two techniques: Principal Components Analysis (PCA) and Sequential Forward Floating Selection (SFFS). The decision about whether a voice record is hypernasal or healthy is taken using a Soft Margin - Support Vector Machine (SM-SVM). Experiments upon recordings of the five Spanish vowels and the words are performed considering three different set of features: (1) the classical approach, (2) the NLD analysis, and (3) the combination of the classical and NLD measures. In general, the accuracies are higher and more stable when the classical and NLD features are combined, indicating that the NLD analysis is complementary to the classical approach

Feature selection in pathological voice classification using dinamyc of component analysis

This paper presents a methodology for the reduction of the training space based on the analysis of the variation of the linear components of the acoustic features. The methodology is applied to the automatic detection of voice disorders by means of stochastic dynamic models. The acoustic features used to model the speech are: MFCC, HNR, GNE, NNE and the energy envelopes. The feature extraction is carried out by means of PCA, and classification is done using discrete and continuous HMMs. The results showed a direct relationship between the principal directions (feature weights) and the classification performance. The dynamic feature analysis by means of PCA reduces the dimension of the original feature space while the topological complexity of the dynamic classifier remains unchanged. The experiments were tested with Kay Elemetrics (DB1) and UPM (DB2) databases. Results showed 91% of accuracy with 30% of computational cost reduction for DB1

Voice pathologies : the most comum features and classification tools

Speech pathologies are quite common in society, however the exams that exist are invasive, making them uncomfortable for patients and depending on the experience of the clinician who performs the assessment. Hence the need to develop non-invasive methods, which allow objective and efficient analysis. Taking this need into account in this work, the most promising list of features and classifiers was identified. As features, jitter, shimmer, HNR, LPC, PLP, and MFCC were identified and as classifiers CNN, RNN and LSTM. This study intends to develop a device to support medical decision, however this article already presents the system interface.info:eu-repo/semantics/publishedVersio

Models and analysis of vocal emissions for biomedical applications

This book of Proceedings collects the papers presented at the 3rd International Workshop on Models and Analysis of Vocal Emissions for Biomedical Applications, MAVEBA 2003, held 10-12 December 2003, Firenze, Italy. The workshop is organised every two years, and aims to stimulate contacts between specialists active in research and industrial developments, in the area of voice analysis for biomedical applications. The scope of the Workshop includes all aspects of voice modelling and analysis, ranging from fundamental research to all kinds of biomedical applications and related established and advanced technologies