Dynamic Influence Networks for Rule-based Models

We introduce the Dynamic Influence Network (DIN), a novel visual analytics technique for representing and analyzing rule-based models of protein-protein interaction networks. Rule-based modeling has proved instrumental in developing biological models that are concise, comprehensible, easily extensible, and that mitigate the combinatorial complexity of multi-state and multi-component biological molecules. Our technique visualizes the dynamics of these rules as they evolve over time. Using the data produced by KaSim, an open source stochastic simulator of rule-based models written in the Kappa language, DINs provide a node-link diagram that represents the influence that each rule has on the other rules. That is, rather than representing individual biological components or types, we instead represent the rules about them (as nodes) and the current influence of these rules (as links). Using our interactive DIN-Viz software tool, researchers are able to query this dynamic network to find meaningful patterns about biological processes, and to identify salient aspects of complex rule-based models. To evaluate the effectiveness of our approach, we investigate a simulation of a circadian clock model that illustrates the oscillatory behavior of the KaiC protein phosphorylation cycle.Comment: Accepted to TVCG, in pres

Group-In: Group Inference from Wireless Traces of Mobile Devices

This paper proposes Group-In, a wireless scanning system to detect static or mobile people groups in indoor or outdoor environments. Group-In collects only wireless traces from the Bluetooth-enabled mobile devices for group inference. The key problem addressed in this work is to detect not only static groups but also moving groups with a multi-phased approach based only noisy wireless Received Signal Strength Indicator (RSSIs) observed by multiple wireless scanners without localization support. We propose new centralized and decentralized schemes to process the sparse and noisy wireless data, and leverage graph-based clustering techniques for group detection from short-term and long-term aspects. Group-In provides two outcomes: 1) group detection in short time intervals such as two minutes and 2) long-term linkages such as a month. To verify the performance, we conduct two experimental studies. One consists of 27 controlled scenarios in the lab environments. The other is a real-world scenario where we place Bluetooth scanners in an office environment, and employees carry beacons for more than one month. Both the controlled and real-world experiments result in high accuracy group detection in short time intervals and sampling liberties in terms of the Jaccard index and pairwise similarity coefficient.Comment: This work has been funded by the EU Horizon 2020 Programme under Grant Agreements No. 731993 AUTOPILOT and No.871249 LOCUS projects. The content of this paper does not reflect the official opinion of the EU. Responsibility for the information and views expressed therein lies entirely with the authors. Proc. of ACM/IEEE IPSN'20, 202

Understanding social behaviors in the indoor environment: a complex network approach

Being able to monitor and analyze human interactions in the indoor environment over time has many architectural applications from spatial planning to post occupancy evaluation. In this paper, we present our interdisciplinary approach that interprets human-spatial interactions as a complex network. We combine methods and techniques from sensor networks, signal processing, data mining, network theory, and information visualization to form a novel framework that facilitates versatile investigations. We will demonstrate the framework with a real-world case study: we have collected and analyzed human-spatial interaction data from a workshop scenario where multiple design projects were conducted within a shared studio space