Answer Set Programming Modulo `Space-Time'

We present ASP Modulo `Space-Time', a declarative representational and computational framework to perform commonsense reasoning about regions with both spatial and temporal components. Supported are capabilities for mixed qualitative-quantitative reasoning, consistency checking, and inferring compositions of space-time relations; these capabilities combine and synergise for applications in a range of AI application areas where the processing and interpretation of spatio-temporal data is crucial. The framework and resulting system is the only general KR-based method for declaratively reasoning about the dynamics of `space-time' regions as first-class objects. We present an empirical evaluation (with scalability and robustness results), and include diverse application examples involving interpretation and control tasks

VRCC-3D+: Qualitative spatial and temporal reasoning in 3 dimensions

Qualitative Spatial Reasoning (QSR) has varying applications in Geographic Information Systems (GIS), visual programming language semantics, and digital image analysis. Systems for spatial reasoning over a set of objects have evolved in both expressive power and complexity, but implementations or usages of these systems are not common. This is partially due to the computational complexity of the operations required by the reasoner to make informed decisions about its surroundings. These theoretical systems are designed to focus on certain criteria, including efficiency of computation, ease of human comprehension, and expressive power. Sadly, the implementation of these systems is frequently left as an exercise for the reader. Herein, a new QSR system, VRCC-3D+, is proposed that strives to maximize expressive power while minimizing the complexity of reasoning and computational cost of using the system. This system is an evolution of RCC-3D; the system and implementation are constantly being refined to handle the complexities of the reasoning being performed. The refinements contribute to the accuracy, correctness, and speed of the implementation. To improve the accuracy and correctness of the implementation, a way to dynamically change error tolerance in the system to more accurately reflect what the user sees is designed. A method that improves the speed of determining spatial relationships between objects by using composition tables and decision trees is introduced, and improvements to the system itself are recommended; by streamlining the relation set and enforcing strict rules for the precision of the predicates that determine the relationships between objects. A potential use case and prototype implementation is introduced to further motivate the need for implementations of QSR systems, and show that their use is not precluded by computational complexity. --Abstract, page iv

Inductive learning spatial attention

This paper investigates the automatic induction of spatial attention from the visual observation of objects manipulated on a table top. In this work, space is represented in terms of a novel observer-object relative reference system, named Local Cardinal System, defined upon the local neighbourhood of objects on the table. We present results of applying the proposed methodology on five distinct scenarios involving the construction of spatial patterns of coloured blocks

Engineering simulations for cancer systems biology

Computer simulation can be used to inform in vivo and in vitro experimentation, enabling rapid, low-cost hypothesis generation and directing experimental design in order to test those hypotheses. In this way, in silico models become a scientific instrument for investigation, and so should be developed to high standards, be carefully calibrated and their findings presented in such that they may be reproduced. Here, we outline a framework that supports developing simulations as scientific instruments, and we select cancer systems biology as an exemplar domain, with a particular focus on cellular signalling models. We consider the challenges of lack of data, incomplete knowledge and modelling in the context of a rapidly changing knowledge base. Our framework comprises a process to clearly separate scientific and engineering concerns in model and simulation development, and an argumentation approach to documenting models for rigorous way of recording assumptions and knowledge gaps. We propose interactive, dynamic visualisation tools to enable the biological community to interact with cellular signalling models directly for experimental design. There is a mismatch in scale between these cellular models and tissue structures that are affected by tumours, and bridging this gap requires substantial computational resource. We present concurrent programming as a technology to link scales without losing important details through model simplification. We discuss the value of combining this technology, interactive visualisation, argumentation and model separation to support development of multi-scale models that represent biologically plausible cells arranged in biologically plausible structures that model cell behaviour, interactions and response to therapeutic interventions

A survey of qualitative spatial representations

Representation and reasoning with qualitative spatial relations is an important problem in artificial intelligence and has wide applications in the fields of geographic information system, computer vision, autonomous robot navigation, natural language understanding, spatial databases and so on. The reasons for this interest in using qualitative spatial relations include cognitive comprehensibility, efficiency and computational facility. This paper summarizes progress in qualitative spatial representation by describing key calculi representing different types of spatial relationships. The paper concludes with a discussion of current research and glimpse of future work