Privacy-Preserving Reengineering of Model-View-Controller Application Architectures Using Linked Data

When a legacy system’s software architecture cannot be redesigned, implementing additional privacy requirements is often complex, unreliable and costly to maintain. This paper presents a privacy-by-design approach to reengineer web applications as linked data-enabled and implement access control and privacy preservation properties. The method is based on the knowledge of the application architecture, which for the Web of data is commonly designed on the basis of a model-view-controller pattern. Whereas wrapping techniques commonly used to link data of web applications duplicate the security source code, the new approach allows for the controlled disclosure of an application’s data, while preserving non-functional properties such as privacy preservation. The solution has been implemented and compared with existing linked data frameworks in terms of reliability, maintainability and complexity

On-premise containerized, light-weight software solutions for Biomedicine

Bioinformatics software systems are critical tools for analysing large-scale biological data, but their design and implementation can be challenging due to the need for reliability, scalability, and performance. This thesis investigates the impact of several software approaches on the design and implementation of bioinformatics software systems. These approaches include software patterns, microservices, distributed computing, containerisation and container orchestration. The research focuses on understanding how these techniques affect bioinformatics software systems’ reliability, scalability, performance, and efficiency. Furthermore, this research highlights the challenges and considerations involved in their implementation. This study also examines potential solutions for implementing container orchestration in bioinformatics research teams with limited resources and the challenges of using container orchestration. Additionally, the thesis considers microservices and distributed computing and how these can be optimised in the design and implementation process to enhance the productivity and performance of bioinformatics software systems. The research was conducted using a combination of software development, experimentation, and evaluation. The results show that implementing software patterns can significantly improve the code accessibility and structure of bioinformatics software systems. Specifically, microservices and containerisation also enhanced system reliability, scalability, and performance. Additionally, the study indicates that adopting advanced software engineering practices, such as model-driven design and container orchestration, can facilitate efficient and productive deployment and management of bioinformatics software systems, even for researchers with limited resources. Overall, we develop a software system integrating all our findings. Our proposed system demonstrated the ability to address challenges in bioinformatics. The thesis makes several key contributions in addressing the research questions surrounding the design, implementation, and optimisation of bioinformatics software systems using software patterns, microservices, containerisation, and advanced software engineering principles and practices. Our findings suggest that incorporating these technologies can significantly improve bioinformatics software systems’ reliability, scalability, performance, efficiency, and productivity.Bioinformatische Software-Systeme stellen bedeutende Werkzeuge für die Analyse umfangreicher biologischer Daten dar. Ihre Entwicklung und Implementierung kann jedoch aufgrund der erforderlichen Zuverlässigkeit, Skalierbarkeit und Leistungsfähigkeit eine Herausforderung darstellen. Das Ziel dieser Arbeit ist es, die Auswirkungen von Software-Mustern, Microservices, verteilten Systemen, Containerisierung und Container-Orchestrierung auf die Architektur und Implementierung von bioinformatischen Software-Systemen zu untersuchen. Die Forschung konzentriert sich darauf, zu verstehen, wie sich diese Techniken auf die Zuverlässigkeit, Skalierbarkeit, Leistungsfähigkeit und Effizienz von bioinformatischen Software-Systemen auswirken und welche Herausforderungen mit ihrer Konzeptualisierungen und Implementierung verbunden sind. Diese Arbeit untersucht auch potenzielle Lösungen zur Implementierung von Container-Orchestrierung in bioinformatischen Forschungsteams mit begrenzten Ressourcen und die Einschränkungen bei deren Verwendung in diesem Kontext. Des Weiteren werden die Schlüsselfaktoren, die den Erfolg von bioinformatischen Software-Systemen mit Containerisierung, Microservices und verteiltem Computing beeinflussen, untersucht und wie diese im Design- und Implementierungsprozess optimiert werden können, um die Produktivität und Leistung bioinformatischer Software-Systeme zu steigern. Die vorliegende Arbeit wurde mittels einer Kombination aus Software-Entwicklung, Experimenten und Evaluation durchgeführt. Die erzielten Ergebnisse zeigen, dass die Implementierung von Software-Mustern, die Zuverlässigkeit und Skalierbarkeit von bioinformatischen Software-Systemen erheblich verbessern kann. Der Einsatz von Microservices und Containerisierung trug ebenfalls zur Steigerung der Zuverlässigkeit, Skalierbarkeit und Leistungsfähigkeit des Systems bei. Darüber hinaus legt die Arbeit dar, dass die Anwendung von SoftwareEngineering-Praktiken, wie modellgesteuertem Design und Container-Orchestrierung, die effiziente und produktive Bereitstellung und Verwaltung von bioinformatischen Software-Systemen erleichtern kann. Zudem löst die Implementierung dieses SoftwareSystems, Herausforderungen für Forschungsgruppen mit begrenzten Ressourcen. Insgesamt hat das System gezeigt, dass es in der Lage ist, Herausforderungen im Bereich der Bioinformatik zu bewältigen und stellt somit ein wertvolles Werkzeug für Forscher in diesem Bereich dar. Die vorliegende Arbeit leistet mehrere wichtige Beiträge zur Beantwortung von Forschungsfragen im Zusammenhang mit dem Entwurf, der Implementierung und der Optimierung von Software-Systemen für die Bioinformatik unter Verwendung von Prinzipien und Praktiken der Softwaretechnik. Unsere Ergebnisse deuten darauf hin, dass die Einbindung dieser Technologien die Zuverlässigkeit, Skalierbarkeit, Leistungsfähigkeit, Effizienz und Produktivität bioinformatischer Software-Systeme erheblich verbessern kann

Towards a virtual research environment for paediatric endocrinology across Europe

Paediatric endocrinology is a medical specialty dealing with variations of physical growth and sexual development in childhood. Genetic anomalies that can cause disorders of sexual development in children are rare. Given this, sharing and collaboration on the small number of cases that occur is needed by clinical experts in the field. The EU-funded EuroDSD project (www.eurodsd.eu) is one such collaboration involving clinical centres and clinical and genetic experts across Europe. Through the establishment of a virtual research environment (VRE) supporting sharing of data and a variety of clinical and bioinformatics analysis tools, EuroDSD aims to provide a research infrastructure for research into disorders of sex development. Security, ethics and information governance are at the heart of this infrastructure. This paper describes the infrastructure that is being built and the inherent challenges in security, availability and dependability that must be overcome for the enterprise to succeed

Advanced EVA system design requirements study

The results are presented of a study to identify specific criteria regarding space station extravehicular activity system (EVAS) hardware requirements. Key EVA design issues include maintainability, technology readiness, LSS volume vs. EVA time available, suit pressure/cabin pressure relationship and productivity effects, crew autonomy, integration of EVA as a program resource, and standardization of task interfaces. A variety of DOD EVA systems issues were taken into consideration. Recommendations include: (1) crew limitations, not hardware limitations; (2) capability to perform all of 15 generic missions; (3) 90 days on-orbit maintainability with 50 percent duty cycle as minimum; and (4) use by payload sponsors of JSC document 10615A plus a Generic Tool Kit and Specialized Tool Kit description. EVA baseline design requirements and criteria, including requirements of various subsystems, are outlined. Space station/EVA system interface requirements and EVA accommodations are discussed in the areas of atmosphere composition and pressure, communications, data management, logistics, safe haven, SS exterior and interior requirements, and SS airlock

Inclusive Educational Review of Software Architectural Styles and Patterns for the Students of the College of Information and Computing Sciences of Cagayan State University

A good architectural design has a high contribution to the success of a system. In addition, this architectural design is useful for the Information Technology (IT) students as their basis of their software development of their capstone project. The utilization of inappropriate architecture can lead to disastrous consequences for IT student researchers. A detailed understanding of software architecture styles is very useful to analyze distributed and complex systems which is the trend of capstone projects. This paper explores the quality attributes of three architecture styles namely shared-nothing, broker, and representational state transfer, which are perceived as beneficial to distributed system architecture that serve as guide to student researchers. This is to provide a picture of the said three key software architecture styles which could be helpful not only for student researchers but also for the software developers by adding references to minimize the uncertainty while selecting the appropriate architectural style for their specific needs. An architectural style must be chosen correctly to obtain all its benefits in the system. In this paper, the three architectural styles are compared on the foundation of various quality attributes derived from ISO 9126-1 standard such as functionality, reliability, usability, efficiency, maintainability, and portability. The results of the study are useful to guide the student researchers in their capstone project and to reduce the number of unsuccessful attempts of software development component of their capstone project

Web application for energy system integration

This bachelor thesis describes the development of a web application that allows users to configure and save simulations for an energy system. The application utilizes a pre-existing simulator pack to generate real-time results, which are displayed to the user in chart form. The development stack includes Sveltekit, FastAPI, and GraphQL, with the latter used to retrieve and display data. The application features a login system and user-specific configuration options, enabling users to tailor simulations to their needs. The system is built to be scalable and easy-to-implement new features such as a better system for storage and automated test. The team focused on long term for this project and made sure it would be easy for other people to work on it later. The resulting application provides an efficient and user-friendly means of simulating energy systems, with potential applications in both research and industry

Web application for energy system

This bachelor thesis describes the development of a web application that allows users to configure and save simulations for an energy system. The application utilizes a pre-existing simulator pack to generate real-time results, which are displayed to the user in chart form. The development stack includes Sveltekit, FastAPI, and GraphQL, with the latter used to retrieve and display data. The application features a login system and user-specific configuration options, enabling users to tailor simulations to their needs. The system is built to be scalable and easy-to-implement new features such as a better system for storage and automated test. The team focused on long term for this project and made sure it would be easy for other people to work on it later. The resulting application provides an efficient and user-friendly means of simulating energy systems, with potential applications in both research and industry