1,609,302 research outputs found

    Mediated data integration and transformation for web service-based software architectures

    Get PDF
    Service-oriented architecture using XML-based web services has been widely accepted by many organisations as the standard infrastructure to integrate heterogeneous and autonomous data sources. As a result, many Web service providers are built up on top of the data sources to share the data by supporting provided and required interfaces and methods of data access in a unified manner. In the context of data integration, problems arise when Web services are assembled to deliver an integrated view of data, adaptable to the specific needs of individual clients and providers. Traditional approaches of data integration and transformation are not suitable to automate the construction of connectors dedicated to connect selected Web services to render integrated and tailored views of data. We propose a declarative approach that addresses the oftenneglected data integration and adaptivity aspects of serviceoriented architecture

    VIGAN: Missing View Imputation with Generative Adversarial Networks

    Full text link
    In an era when big data are becoming the norm, there is less concern with the quantity but more with the quality and completeness of the data. In many disciplines, data are collected from heterogeneous sources, resulting in multi-view or multi-modal datasets. The missing data problem has been challenging to address in multi-view data analysis. Especially, when certain samples miss an entire view of data, it creates the missing view problem. Classic multiple imputations or matrix completion methods are hardly effective here when no information can be based on in the specific view to impute data for such samples. The commonly-used simple method of removing samples with a missing view can dramatically reduce sample size, thus diminishing the statistical power of a subsequent analysis. In this paper, we propose a novel approach for view imputation via generative adversarial networks (GANs), which we name by VIGAN. This approach first treats each view as a separate domain and identifies domain-to-domain mappings via a GAN using randomly-sampled data from each view, and then employs a multi-modal denoising autoencoder (DAE) to reconstruct the missing view from the GAN outputs based on paired data across the views. Then, by optimizing the GAN and DAE jointly, our model enables the knowledge integration for domain mappings and view correspondences to effectively recover the missing view. Empirical results on benchmark datasets validate the VIGAN approach by comparing against the state of the art. The evaluation of VIGAN in a genetic study of substance use disorders further proves the effectiveness and usability of this approach in life science.Comment: 10 pages, 8 figures, conferenc

    ISPIDER Central: an integrated database web-server for proteomics

    Get PDF
    Despite the growing volumes of proteomic data, integration of the underlying results remains problematic owing to differences in formats, data captured, protein accessions and services available from the individual repositories. To address this, we present the ISPIDER Central Proteomic Database search (http://www.ispider.manchester.ac.uk/cgi-bin/ProteomicSearch.pl), an integration service offering novel search capabilities over leading, mature, proteomic repositories including PRoteomics IDEntifications database (PRIDE), PepSeeker, PeptideAtlas and the Global Proteome Machine. It enables users to search for proteins and peptides that have been characterised in mass spectrometry-based proteomics experiments from different groups, stored in different databases, and view the collated results with specialist viewers/clients. In order to overcome limitations imposed by the great variability in protein accessions used by individual laboratories, the European Bioinformatics Institute's Protein Identifier Cross-Reference (PICR) service is used to resolve accessions from different sequence repositories. Custom-built clients allow users to view peptide/protein identifications in different contexts from multiple experiments and repositories, as well as integration with the Dasty2 client supporting any annotations available from Distributed Annotation System servers. Further information on the protein hits may also be added via external web services able to take a protein as input. This web server offers the first truly integrated access to proteomics repositories and provides a unique service to biologists interested in mass spectrometry-based proteomics

    Manufacturing and services in Italian labour market areas in an historical perspective (1981-1996)

    Get PDF
    The basic hypothesis of this paper is the existence of strong territorial disparities in services development. In many areas a strict integration emerges between manufacturing production and endowment of tertiary functions; in other regions the sparse presence of services may result in belated development or slow growth. From a sectoral point of view, the analysis goes beyond the classical tripartition of industries, proposing a classification of services based both on the nature of the service given and the features of their users. From a geographical point of view, a territorial grid based on local labour market areas as proposed by Istat [1997] is adopted. The long-term analysis - based on Census data from 1981 to 1996 - allows to identify territorial regularities in development patterns across LLMAs, with respect to manufacturing and services and to different growth paths (convergence, externalisation, integration, ...).

    Benchmarking and viability assessment of optical packet switching for metro networks

    Get PDF
    Optical packet switching (OPS) has been proposed as a strong candidate for future metro networks. This paper assesses the viability of an OPS-based ring architecture as proposed within the research project DAVID (Data And Voice Integration on DWDM), funded by the European Commission through the Information Society Technologies (IST) framework. Its feasibility is discussed from a physical-layer point of view, and its limitations in size are explored. Through dimensioning studies, we show that the proposed OPS architecture is competitive with respect to alternative metropolitan area network (MAN) approaches, including synchronous digital hierarchy, resilient packet rings (RPR), and star-based Ethernet. Finally, the proposed OPS architectures are discussed from a logical performance point of view, and a high-quality scheduling algorithm to control the packet-switching operations in the rings is explained
    corecore