Verification of Unstructured Grid Adaptation Components

Adaptive unstructured grid techniques have made limited impact on production analysis workflows where the control of discretization error is critical to obtaining reliable simulation results. Recent progress has matured a number of independent implementations of flow solvers, error estimation methods, and anisotropic grid adaptation mechanics. Known differences and previously unknown differences in grid adaptation components and their integrated processes are identified here for study. Unstructured grid adaptation tools are verified using analytic functions and the Code Comparison Principle. Three analytic functions with different smoothness properties are adapted to show the impact of smoothness on implementation differences. A scalar advection-diffusion problem with an analytic solution that models a boundary layer is adapted to test individual grid adaptation components. Laminar flow over a delta wing and turbulent flow over an ONERA M6 wing are verified with multiple, independent grid adaptation procedures to show consistent convergence to fine-grid forces and a moment. The scalar problems illustrate known differences in a grid adaptation component implementation and a previously unknown interaction between components. The wing adaptation cases in the current study document a clear improvement to existing grid adaptation procedures. The stage is set for the infusion of verified grid adaptation into production fluid flow simulations

Blockchain-based Governance, Risk Management, and Compliance for Fractional Ownership: Design and Implementation of A Decentralized Autonomous Agent System

Fractional ownership makes homeownership more affordable. But there are challenges in a fractional ownership real estate transaction (FORET) regarding governance, risk management and compliance (GRC) processes. Centralized GRC solutions are less effective in managing the tiered structure of communications in a FORET, which can lead to principal-agent problems such as information asymmetry, risk aversion, and moral hazard. In this research we investigate how these principal-agent problems in FORET could be mitigated. Using an agency theory perspective, we adopt a design science multimethodological research approach. We propose conceptual and system artefacts to support the design and implementation of a decentralized autonomous agent system. These artefacts deliver a formal problem representation structure related to centralized GRC in fractional ownership. We illustrate our solution with a system prototype and implementation. We evaluate the research outputs and compare them with existing GRC systems. This paper contributes to the understanding of GRC in supporting fractional ownership decision making

Tube-Gel: A Fast and Effective Sample Preparation Method for High-Throughput Quantitative Proteomics

International audienceSample preparation is a key step in proteomics workflows. Tube-gel (TG) is a fast and repeatable sample preparation method that consists in the instantaneous trapping of the sample in a polyacrylamide gel matrix. It takes advantage of in-gel sample preparations by allowing the use of high concentrations of sodium-dodecyl sulfate but avoids the time-consuming step of electrophoresis. Therefore, TG limits the sample handling and is thus particularly suitable for high-throughput quantitative proteomics when large sample numbers have to be processed, as it is often the case in biomarker research and clinical proteomics projects

High-Throughput Fingerprinting of Rhizobial Free Fatty Acids by Chemical Thin-Film Deposition and Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry

Fatty acids (FAs) represent an important class of metabolites, impacting on membrane building blocks and signaling compounds in cellular regulatory networks. In nature, prokaryotes are characterized with the most impressing FA structural diversity and the highest relative content of free fatty acids (FFAs). In this context, nitrogen-fixing bacteria (order Rhizobiales), the symbionts of legumes, are particularly interesting. Indeed, the FA profiles influence the structure of rhizobial nodulation factors, required for successful infection of plant root. Although FA patterns can be assessed by gas chromatography—(GC-) and liquid chromatography—mass spectrometry (LC-MS), sample preparation for these methods is time-consuming and quantification suffers from compromised sensitivity, low stability of derivatives and artifacts. In contrast, matrix-assisted laser desorption/ionization-time of flight mass spectrometry (MALDI-TOF-MS) represents an excellent platform for high-efficient metabolite fingerprinting, also applicable to FFAs. Therefore, here we propose a simple and straightforward protocol for high-throughput relative quantification of FFAs in rhizobia by combination of Langmuir technology and MALDI-TOF-MS featuring a high sensitivity, accuracy and precision of quantification. We describe a step-by-step procedure comprising rhizobia culturing, pre-cleaning, extraction, sample preparation, mass spectrometric analysis, data processing and post-processing. As a case study, a comparison of the FFA metabolomes of two rhizobia species—Rhizobium leguminosarum and Sinorhizobium meliloti, demonstrates the analytical potential of the protocol

Computational Fluid Dynamics Methods Used in the Development of the Space Launch System Liftoff and Transition Lineloads Databases

The objective of this paper is to document the reasoning and trade studies that supported the selection of appropriate tools for constructing aerodynamic lineload databases for the Liftoff and Transition phases of flight for launch vehicles. These decisions were made amid the maturation of an evolving workflow for generating databases on variants of the Space Launch System launch vehicle, with most being based on results from brief developmental studies performed in response to specific, unforeseen challenges that were encountered in analyzing a given configuration. This report is intended to provide a summary of the results and the decision-making processes chronologically over the design cycles of various configurations, starting with isolated free-air bodies for the Block 1 Crew, then the Block 1B Crew and Cargo configurations, and most recently the Block 1B Crew configuration in proximity to the launch tower. The results from these analyses led to the selection of the CREATE-AV Kestrel flowsolver for simulating these problems. The need to accurately capture the expected leeward-wake flow field characteristics required the use of Delayed Detached Eddy Simulation (DDES) method, for which the vorticity magnitude was employed as the solution Adaptive Mesh Refinement (AMR) function over the off-body Cartesian grid region. In addition, the Spalart-Allmaras (SA) model is used to account for the flow turbulence effects

A Vortex Damping Outflow Forcing for Multiphase Flows with Sharp Interfacial Jumps

Outflow boundaries play an important role in multiphase fluid dynamics simulations involving low Weber numbers and large jump in physical variables. Inadequate treatment of these jumps at outflow generates undesirable fluid disturbances within the computational domain. We introduce a forcing term for incompressible Navier-Stokes equations that is coupled with a fixed pressure outflow boundary condition to enable stable exit of these disturbances from the domain boundary. The forcing term acts as a damping mechanism to control vortices that are generated by droplets/bubbles in multiphase flows, and is designed to be a general formulation that can be applied to a variety of fluid-flow simulations involving phase transition and sharp interfacial jumps. Validation cases are provided to demonstrate applicability of this formulation to pool and flow boiling problems, where bubble induced vortices during evaporation and condensation can lead to instabilities at outflow boundaries that eventually propagate downstream to corrupt numerical solution. Computational experiments are performed using \flashx, which is a composable open-source software instrument designed for multiscale fluid dynamics simulations on heterogenous architectures.Comment: Preprint Submitted to Journal of Computational Physic

Verification of Unstructured Grid Adaptation Components

Adaptive unstructured grid techniques have made limited impact on production analysis workflows where the control of discretization error is critical to obtaining reliable simulation results. Recent progress has matured a number of independent implementations of flow solvers, error estimation methods, and anisotropic grid adaptation mechanics. Known differences and previously unknown differences in grid adaptation components and their integrated processes are identified here for study. Unstructured grid adaptation tools are verified using analytic functions and the Code Comparison Principle. Three analytic functions with different smoothness properties are adapted to show the impact of smoothness on implementation differences. A scalar advection-diffusion problem with an analytic solution that models a boundary layer is adapted to test individual grid adaptation components. The scalar problems illustrate known differences in a grid adaptation component implementation and a previously unknown interaction between components. Laminar flow over a delta wing is verified with multiple, independent grid adaptation procedures to show consistent convergence to fine-grid forces and pitching moment

Collaborative Design of a Business Jet Family Using the AGILE 4.0 MBSE Environment

This paper presents the collaborative model-based design of a business jet family. In family design, a trade-off is made between aircraft performance, reducing fuel burn, and commonality, reducing manufacturing costs. The family is designed using Model-Based Systems Engineering (MBSE) methods developed in the AGILE 4.0 project. The EC-funded AGILE 4.0 project extends the scope of the preliminary aircraft design process to also include systems engineering phases and new design domains like manufacturing, maintenance, and certification. Stakeholders, needs, requirements, and architecture models of the business jet family are presented. Then, the collaborative Multidisciplinary Design Analysis and Optimization (MDAO) capabilities are used to integrate various aircraft design disciplines, including overall aircraft design, onboard systems design, wing structural sizing, tailplane sizing, mission analysis, and cost estimation. Decisions regarding the degree of commonality are implemented by optionally fixing the design of a shared component when sizing an aircraft