Local Motion Planner for Autonomous Navigation in Vineyards with a RGB-D Camera-Based Algorithm and Deep Learning Synergy

With the advent of agriculture 3.0 and 4.0, researchers are increasingly focusing on the development of innovative smart farming and precision agriculture technologies by introducing automation and robotics into the agricultural processes. Autonomous agricultural field machines have been gaining significant attention from farmers and industries to reduce costs, human workload, and required resources. Nevertheless, achieving sufficient autonomous navigation capabilities requires the simultaneous cooperation of different processes; localization, mapping, and path planning are just some of the steps that aim at providing to the machine the right set of skills to operate in semi-structured and unstructured environments. In this context, this study presents a low-cost local motion planner for autonomous navigation in vineyards based only on an RGB-D camera, low range hardware, and a dual layer control algorithm. The first algorithm exploits the disparity map and its depth representation to generate a proportional control for the robotic platform. Concurrently, a second back-up algorithm, based on representations learning and resilient to illumination variations, can take control of the machine in case of a momentaneous failure of the first block. Moreover, due to the double nature of the system, after initial training of the deep learning model with an initial dataset, the strict synergy between the two algorithms opens the possibility of exploiting new automatically labeled data, coming from the field, to extend the existing model knowledge. The machine learning algorithm has been trained and tested, using transfer learning, with acquired images during different field surveys in the North region of Italy and then optimized for on-device inference with model pruning and quantization. Finally, the overall system has been validated with a customized robot platform in the relevant environment

Camera localization using trajectories and maps

We propose a new Bayesian framework for automatically determining the position (location and orientation) of an uncalibrated camera using the observations of moving objects and a schematic map of the passable areas of the environment. Our approach takes advantage of static and dynamic information on the scene structures through prior probability distributions for object dynamics. The proposed approach restricts plausible positions where the sensor can be located while taking into account the inherent ambiguity of the given setting. The proposed framework samples from the posterior probability distribution for the camera position via data driven MCMC, guided by an initial geometric analysis that restricts the search space. A Kullback-Leibler divergence analysis is then used that yields the final camera position estimate, while explicitly isolating ambiguous settings. The proposed approach is evaluated in synthetic and real environments, showing its satisfactory performance in both ambiguous and unambiguous settings

Learning to See the Wood for the Trees: Deep Laser Localization in Urban and Natural Environments on a CPU

Localization in challenging, natural environments such as forests or woodlands is an important capability for many applications from guiding a robot navigating along a forest trail to monitoring vegetation growth with handheld sensors. In this work we explore laser-based localization in both urban and natural environments, which is suitable for online applications. We propose a deep learning approach capable of learning meaningful descriptors directly from 3D point clouds by comparing triplets (anchor, positive and negative examples). The approach learns a feature space representation for a set of segmented point clouds that are matched between a current and previous observations. Our learning method is tailored towards loop closure detection resulting in a small model which can be deployed using only a CPU. The proposed learning method would allow the full pipeline to run on robots with limited computational payload such as drones, quadrupeds or UGVs.Comment: Accepted for publication at RA-L/ICRA 2019. More info: https://ori.ox.ac.uk/esm-localizatio

Towards secure & robust PNT for automated systems

This dissertation makes four contributions in support of secure and robust position, navigation, and timing (PNT) for automated systems. The first two relate to PNT security while the latter two address robust positioning for automated ground vehicles. The first contribution is a fundamental theory for provably-secure clock synchronization between two agents in a distributed automated system. All one-way synchronization protocols, such as those based on the Global Positioning System (GPS) and other Global Navigation Satellite Systems (GNSS), are shown to be vulnerable to man-in-the-middle delay attacks. This contribution is the first to identify the necessary and sufficient conditions for provably secure clock synchronization. The second contribution, also related to PNT security, is a three-year study of the world-wide GPS interference landscape based on data from a dual-frequency GNSS receiver operating continuously on the International Space Station (ISS). This work is the first publicly-reported space-based survey of GNSS interference, and unveils previously-unreported GNSS interference activity. The third contribution is a novel ground vehicle positioning technique that is robust to GNSS signal blockage, poor lighting conditions, and adverse weather events such as heavy rain and dense fog. The technique relies on sensors that are commonly available on automated vehicles and are insensitive to lighting and inclement weather: automotive radar, low-cost inertial measurement units (IMUs), and GNSS. Remarkably, it is shown that, given a prior radar map, the proposed technique operating on data from off-the-shelf all-weather automotive sensors can maintain sub-50-cm horizontal position accuracy during 60 min of GNSS-denied driving in downtown Austin, TX. This dissertation’s final contribution is an analysis and demonstration of the feasibility of crowd-sourced digital mapping for automated vehicles. Localization techniques, such as the one described in the previous contribution, rely on such digital maps for accuracy and robustness. A key enabler for large-scale up-to-date maps is enlisting the help of the very consumer vehicles that need the map to build and update it. A method for fusing multi-session vision data into a unified digital map is developed. The asymptotic limit of such a map’s globally-referenced position accuracy is explored for the case in which the mapping agents rely on low-cost GNSS receivers performing standard code-phase-based navigation. Experimental validation along a semi-urban route shows that low-cost consumer vehicles incrementally tighten the accuracy of the jointly-optimized digital map over time enough to support sub-lane-level positioning in a global frame of reference.Electrical and Computer Engineerin

Covalent targeting of the vacuolar H+-ATPase activates autophagy via mTORC1 inhibition.

Autophagy is a lysosomal degradation pathway that eliminates aggregated proteins and damaged organelles to maintain cellular homeostasis. A major route for activating autophagy involves inhibition of the mTORC1 kinase, but current mTORC1-targeting compounds do not allow complete and selective mTORC1 blockade. Here, we have coupled screening of a covalent ligand library with activity-based protein profiling to discover EN6, a small-molecule in vivo activator of autophagy that covalently targets cysteine 277 in the ATP6V1A subunit of the lysosomal v-ATPase, which activates mTORC1 via the Rag guanosine triphosphatases. EN6-mediated ATP6V1A modification decouples the v-ATPase from the Rags, leading to inhibition of mTORC1 signaling, increased lysosomal acidification and activation of autophagy. Consistently, EN6 clears TDP-43 aggregates, a causative agent in frontotemporal dementia, in a lysosome-dependent manner. Our results provide insight into how the v-ATPase regulates mTORC1, and reveal a unique approach for enhancing cellular clearance based on covalent inhibition of lysosomal mTORC1 signaling