12 research outputs found

    Dmarc: A Framework For The Integration Of Dmaic And Dmadv

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    The Lean Six Sigma methodology is being applied extensively to tackle many quality related issues in many processes of today s industries. Various companies have benefited greatly from the adoption of Six Sigma and Lean engineering concepts since their introduction, and continue to do so. The DMAIC method that is traditionally adopted in the implementation of the Lean Six Sigma methodology has proven to yield cost saving results in most cases. Yet, industries have found that just improvement of existent process and products to reduce defects, does not quench the customer s growing thirst for greater quality. In order to tackle variation and defects pro actively, the initiative to achieve Six Sigma level of quality (3.4 DPMO) or greater is being infused into the design of new products using the Design for Six Sigma (DFSS) methodology, through systematic approaches such as DMADV. This research integrates the DMADV approach into the classic DMAIC methodology through a framework, DMARC, which details the improvement an existing process through re design. It provides a systematic approach to avoid the mis direction of projects into following the path of continued improvement of existing processes that are deemed to be beyond such efforts. A real life industrial case: a successfully completed Lean Six Sigma project, tackling the downtime of the Launch Pad Meteorological System at Launch Pads 39A and B at the Kennedy Space Center, was studied to exemplify the possibility of the achievement of greater results from the implementation of the DMARC framework

    Procedimentos de otimização no planejamento e controle da qualidade de produtos e processos

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    Tese (doutorado) - Universidade Federal de Santa Catarina, Florianópolis, 1996.Procedimentos de otimização para a melhoria da qualidade de produtos e processos para os três tipos de características de qualidade: o maior é melhor, o menor é melhor e o nominal é melhor. Os procedimentos compreendem três etapas: o planejamento estatístico dos experimentos, a modelagem das respostas e a otimização das respostas. Os problemas são classificados como bicritério se é necessário investigar apenas uma característica de qualidade e será classificado como multicritério se for necessário investigar mais que uma característica de qualidade

    Integrated design under uncertainty for pharmaceutical processes

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    in pharmaceutical process development there is frequently a large element of process uncertainty since knowledge of the mechanisms of production and separation is often limited. The overall objective of this thesis is the development of a general methodology which combines process modelling with uncertainty techniques to support the process development of complete integrated sequences. In a structured approach the uncertainty can be managed and improved process performance may be obtained. The major concept of this work is the integration of stochastic methods into a general framework for batch and continuous process models, consisting of two main parts. The first combines systematic modelling procedures with Hammersley sampling based Uncertainty Analysis and a range of sample-based Sensitivity Analysis techniques, used to quantify predicted performance uncertainty and identify key uncertainty contributions. In the second, a stochastic optimisation approach is employed to solve different problems under uncertainty. The methodology was implemented on two case studies. The first study investigated a batch reactor process. Some undesirable performance characteristics were observed when the published nominal optimal isothermal operating policy was implemented in the uncertain system. It was found that a robust operating policy significantly improved the total process time characteristic but not the impurity content and an alternative non-isothermal policy strategy would be a better option. The second study investigated a complete process sequence. As models developed with incoming data, uncertainty in the reaction and crystallisation parameters were critical to the endpoint quality criteria. Expected performance was improved by considering the propagation of uncertainty in the complete process. Four different flowsheets were compared, considering profitability and control tolerance criteria under uncertainty. The case study results indicate the importance in considering uncertainty systematically and quantitatively when conventional modelling techniques are employed. The methodology showed the opportunity to improve process performance potential and provide more realistic information to support pharmaceutical process development

    Proceedings /5th International Symposium on Industrial Engineering – SIE2012, June 14-15, 2012., Belgrade

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    editors Dragan D. Milanović, Vesna Spasojević-Brkić, Mirjana Misit

    Proceedings /5th International Symposium on Industrial Engineering – SIE2012, June 14-15, 2012., Belgrade

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    editors Dragan D. Milanović, Vesna Spasojević-Brkić, Mirjana Misit

    Evaluation of railway performance through quality of service

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    Railways worldwide have experienced unprecedented growth over the last decade. The infrastructure of many European railways is becoming increasingly saturated, while the operators face strong demands to increase services and carry more passengers and freight. There has been a high demand for performance improvement, to provide better service to customers. This problem is drawing increasing attention from many parties within and beyond the railway industry. In this research, the author first reviewed and analysed the existing performance measures used in railway transportation. A new generic framework for the measurement and improvement of railway network performance has been proposed, based on the concept of quality of service. The key factors affecting quality of service are identified and analysed. Secondly, the quantification of performance has been identified based on the Quality of Service framework. Multi criteria decision making has been applied to determine the weights of each Key Performance Indicator in the framework. Finally, factors within the railway system have been analysed for their impact on performance with a sensitivity analysis, to support the development of performance improvement plans. A case study has been conveyed to show the influence of the system properties on the performance measured by quality of service

    Role of variance in manufacturing system design : the impact on capacity planning and capital investment decisions

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    Thesis (M.S.)--Massachusetts Institute of Technology, Dept. of Mechanical Engineering, 1997.Includes bibliographical references (p. 277-284).by Joel W. Cain.M.S
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