152 research outputs found
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Building Better Exoskeletons: Understanding How Design Affects Robot Assisted Gait Training
Physical therapy is a field with ever increasing demands as the population ages, resulting in a larger number of individuals living with impairments. Therapy is both physically intensive and time intensive for physical therapists, and can require more than one therapist per patient. The use of technology can reduce both these physical and time demands if appropriately applied, while improving repeatability and providing quantitative evaluation of performance. Through these abilities, it may also improve the quality of life for patients. The work presented here explores how the mechanical and controller design of exoskeletons can be used to improve adaptations to new gait patterns in healthy individuals. Armed with this knowledge, new treatment methods can be adapted, applied, and validated for impaired populations with the intention of recovering a more natural gait pattern.
First, the ALEX II device is presented. It is a unilateral device, designed to aid in gait training for stroke survivors. The previous version, ALEX I, had several limitations in terms of pelvic freedom, leg range of motion, and the support of the gravitational load. ALEX II was designed to address these issues. Next, a study is presented, using healthy young adults (N=30), in which ALEX II was used to explore how the amount of freedom allowed at the pelvis during gait training affects the level of adaptation subjects are able to achieve. This was evaluated for five separate configurations which resemble existing exoskeletons. It was found that intermediate levels of pelvic freedom degrade the amount of adaptation and that pelvic translation contributes more to this effect than hip abduction/adduction.
The next work concerns the design of ALEX III, a bilateral device with twelve active degrees-of-freedom. ALEX III was created to increase the ability to explore the functionality required for gait training, which is why it is capable of controlling 4 degrees-of-freedom at each leg, and 4 degrees-of-freedom at the pelvis. This is followed by the the design of a new type of haptic feedback which utilizes a variable, viscous damping field, which increases the damping coeffiecent as the subject moves away from a specified path. This feedback type was tested in a set of experiments in healthy young adults. The first study (N=32) compared four different settings for the new feedback, finding that while all groups demonstrated adaptations in gait, the lowest rate of change of the damping field exhibited less adaptation. The final study (N=36) compared this haptic feedback to two previously used haptic feedback types. The previously used feedback strategies used a force that pushed the leg either towards or away from the desired path. All three of these strategies were found to produce similar levels of adaptation, however the damping field used much less external force. These findings may change the way exoskeletons for gait training are designed and increase their accessibility.
While all the findings need to be validated in impaired populations they can still inform the design of future exoskeletons. The first finding, that providing an intermediate amount of freedom to the pelvis can interfere with gait training, suggests that future devices should have very high amounts of freedom or very restricted pelvic motions. The final finding, that damping fields can be used to induce gait adaptations using a much lower force, can drastically change exoskeleton design and how robotic therapy is provided. Exoskeletons can be made lighter as a result of the force being highly reduced so that lighter weight components can be used, and the dissipative nature of the force reduces dependence on heavy power sources because regenerative breaking can be used to power the device. These factors also make it possible to for devices to be used overground, which may make training more transferable to the real world
A robotic system to train activities of daily living in a virtual environment
In the past decade, several arm rehabilitation robots have been developed to assist neurological patients during therapy. Early devices were limited in their number of degrees of freedom and range of motion, whereas newer robots such as the ARMin robot can support the entire arm. Often, these devices are combined with virtual environments to integrate motivating game-like scenarios. Several studies have shown a positive effect of game-playing on therapy outcome by increasing motivation. In addition, we assume that practicing highly functional movements can further enhance therapy outcome by facilitating the transfer of motor abilities acquired in therapy to daily life. Therefore, we present a rehabilitation system that enables the training of activities of daily living (ADL) with the support of an assistive robot. Important ADL tasks have been identified and implemented in a virtual environment. A patient-cooperative control strategy with adaptable freedom in timing and space was developed to assist the patient during the task. The technical feasibility and usability of the system was evaluated with seven healthy subjects and three chronic stroke patient
Patient-cooperative control increases active participation of individuals with SCI during robot-aided gait training
ABSTRACT: BACKGROUND: Manual body weight supported treadmill training and robot-aided treadmill training are frequently used techniques for the gait rehabilitation of individuals after stroke and spinal cord injury. Current evidence suggests that robot-aided gait training may be improved by making robotic behavior more patient-cooperative. In this study, we have investigated the immediate effects of patient-cooperative versus non-cooperative robot-aided gait training on individuals with incomplete spinal cord injury (iSCI). METHODS: Eleven patients with iSCI participated in a single training session with the gait rehabilitation robot Lokomat. The patients were exposed to four different training modes in random order: During both non-cooperative position control and compliant impedance control, fixed timing of movements was provided. During two variants of the patient-cooperative path control approach, free timing of movements was enabled and the robot provided only spatial guidance. The two variants of the path control approach differed in the amount of additional support, which was either individually adjusted or exaggerated. Joint angles and torques of the robot as well as muscle activity and heart rate of the patients were recorded. Kinematic variability, interaction torques, heart rate and muscle activity were compared between the different conditions. RESULTS: Patients showed more spatial and temporal kinematic variability, reduced interaction torques, a higher increase of heart rate and more muscle activity in the patient-cooperative path control mode with individually adjusted support than in the non-cooperative position control mode. In the compliant impedance control mode, spatial kinematic variability was increased and interaction torques were reduced, but temporal kinematic variability, heart rate and muscle activity were not significantly higher than in the position control mode. CONCLUSIONS: Patient-cooperative robot-aided gait training with free timing of movements made individuals with iSCI participate more actively and with larger kinematic variability than non-cooperative, position-controlled robot-aided gait training
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A Novel Design of a Cable-driven Active Leg Exoskeleton (C-ALEX) and Gait Training with Human Subjects
Exoskeletons for gait training commonly use a rigid-linked "skeleton" which makes them heavy and bulky. Cable-driven exoskeletons eliminate the rigid-linked skeleton structure, therefore creating a lighter and more transparent design. Current cable-driven leg exoskeletons are limited to gait assistance use. This thesis presented the Cable-driven Active Leg Exoskeleton (C-ALEX) designed for gait retraining and rehabilitation. Benefited from the cable-driven design, C-ALEX has minimal weight and inertia (4.7 kg) and allows all the degrees-of-freedom (DoF) of the leg of the user. C-ALEX uses an assist-as-needed (AAN) controller to train the user to walk in a new gait pattern.
A preliminary design of C-ALEX was first presented, and an experiment was done with this preliminary design to study the effectiveness of the AAN controller. The result on six healthy subjects showed that the subjects were able to follow a new gait pattern significantly more accurately with the help of the AAN controller. After this experiment, C-ALEX was redesigned to improve its functionality. The improved design of C-ALEX is lighter, has more DoFs and larger range-of-motion. The controller of the improved design improved the continuity of the generated cable tensions and added the function to estimate the phase of the gait of the user in real-time.
With the improved design of C-ALEX, an experiment was performed to study the effect of the weight and inertia of an exoskeleton on the gait of the user. C-ALEX was used to simulate exoskeletons with different levels of weight and inertia by adding extra mass and change the weight compensation level. The result on ten subjects showed that adding extra mass increased step length and reduced knee flexion. Compensating the weight of the mass partially restored the knee flexion but not the step length, implying that the inertia of the mass is responsible for the change. This study showed the distinctive effect of weight and inertia on gait and demonstrated the benefit of a lightweight exoskeleton.
C-ALEX was designed for gait training and rehabilitation, and its training effectiveness was studied in nine healthy subjects and a stroke patient. The healthy subjects trained with C-ALEX to walk in a new gait pattern with 30% increase in step height for 40 min. After the training, the subjects were able to closely repeat the trained gait pattern without C-ALEX, and the step height of the subjects increased significantly. A stroke patient also tested C-ALEX for 40 minutes and showed short-term improvements in step length, step height, and knee flexion after training. The result showed the effectiveness of C-ALEX in gait training and its potential to be used in stroke rehabilitation
Robotic design and modelling of medical lower extremity exoskeletons
This study aims to explain the development of the robotic Lower Extremity Exoskeleton (LEE) systems between 1960
and 2019 in chronological order. The scans performed in the exoskeleton system’s design have shown that a modeling
program, such as AnyBody, and OpenSim, should be used first to observe the design and software animation, followed
by the mechanical development of the system using sensors and motors. Also, the use of OpenSim and AnyBody
musculoskeletal system software has been proven to play an essential role in designing the human-exoskeleton by
eliminating the high costs and risks of the mechanical designs. Furthermore, these modeling systems can enable rapid
optimization of the LEE design by detecting the forces and torques falling on the human muscles
Novel Information About The Kinetic Effects Of Equine Shoe Modifications And Kinematic Effects Of Human Digital Devices For Improved Performance In Both Species
Equine shoes are frequently modified to enhance traction for horses that travel on paved surfaces for work, pleasure, or entertainment. Little is known about other common shoe modifications used to enhance traction like calks, tungsten carbide granules, or plastic composition. This information is vital to shoe design to protect the safety and welfare of all service, working, and leisure horses. The objective of the first part of this thesis was to quantify the effect of shoes with and without traction adaptions on kinetic measures in non-lame, light breed horses at a trot. Kinetic data was collected with a force platform from horses while unshod (U) and subsequently shod in random order with five distinct shoes: standard (S), high profile-low surface area calk (HC), low profile-high surface area calk (LC), thin layer tungsten carbide (TLC), and plastic-steel composite (C). Results indicate that in the forelimbs, peak vertical force increased with C versus S (P=0.0001), HC (P=0.0049), LC (P= 0.0110), and TLC (P=0.0246) shoes. In the hind limbs, peak braking force increased with C versus S (PPPP=0.0041). It increased with TLC versus HC (PPP=0.0079) and S shoe (P=0.0474). The human wrist (radiocarpal joints) has complex anatomy and motion that likely contributes to overuse injuries. Digital device use requires distinct wrist motions that may contribute to tissue damage with frequent, prolonged use and static loading. The second part of the thesis aimed to quantify wrist motion in radial-ulnar deviation and flexion-extension planes for use of digital devices and their manual counterparts in dominant and non-dominant hands of male and female professionals. Twelve subjects completed 4 paired daily living activities using digital and manual devices. Left and right wrist 3D motion was recorded with eight markers of a wireless, active motion detection system. This study established baseline values for medial and lateral radiocarpal extension and radial-ulnar deviation angles and ROM using digital devices. Both sex, handedness, and device size influence wrist motion
A unilateral robotic knee exoskeleton to assess the role of natural gait assistance in hemiparetic patients.
Background: Hemiparetic gait is characterized by strong asymmetries that can severely affect the quality of life of
stroke survivors. This type of asymmetry is due to motor deficits in the paretic leg and the resulting compensations in
the nonparetic limb. In this study, we aimed to evaluate the effect of actively promoting gait symmetry in hemiparetic
patients by assessing the behavior of both paretic and nonparetic lower limbs. This paper introduces the design and
validation of the REFLEX prototype, a unilateral active knee–ankle–foot orthosis designed and developed to naturally
assist the paretic limbs of hemiparetic patients during gait.
Methods: REFLEX uses an adaptive frequency oscillator to estimate the continuous gait phase of the nonparetic
limb. Based on this estimation, the device synchronically assists the paretic leg following two different control
strategies: (1) replicating the movement of the nonparetic leg or (2) inducing a healthy gait pattern for the paretic
leg. Technical validation of the system was implemented on three healthy subjects, while the effect of the generated
assistance was assessed in three stroke patients. The effects of this assistance were evaluated in terms of interlimb
symmetry with respect to spatiotemporal gait parameters such as step length or time, as well as the similarity
between the joint’s motion in both legs.
Results: Preliminary results proved the feasibility of the REFLEX prototype to assist gait by reinforcing symmetry. They
also pointed out that the assistance of the paretic leg resulted in a decrease in the compensatory strategies developed
by the nonparetic limb to achieve a functional gait. Notably, better results were attained when the assistance
was provided according to a standard healthy pattern, which initially might suppose a lower symmetry but enabled a
healthier evolution of the motion of the nonparetic limb.
Conclusions: This work presents the preliminary validation of the REFLEX prototype, a unilateral knee exoskeleton for
gait assistance in hemiparetic patients. The experimental results indicate that assisting the paretic leg of a hemiparetic
patient based on the movement of their nonparetic leg is a valuable strategy for reducing the compensatory mechanisms
developed by the nonparetic limb.post-print6406 K
Design, implementation and control of an overground gait and balance trainer with an active pelvis-hip exoskeleton
Human locomotion is crucial for performing activities of daily living and any disability in gait causes a significant decrease in the quality of life. Gait rehabilitation therapy is imperative to improve adverse effects caused by such disabilities. Gait therapies are known to be more effective when they are intense, repetitive, and allow for active involvement of patients. Robotic devices excel in performing repetitive gait rehabilitation therapies as they can eliminate the physical burden of the therapist, enable safe and versatile training with increased intensity, while allowing quantitative measurements of patient progress. Gait therapies need to be applied to specific joints of patients such that the joints work in a coordinated and repetitious sequence to generate a natural gait pattern. Six determinants of gait pattern have been identified that lead to efficient locomotion and any irregularities in these determinants result in pathological gaits. Three of these six basic gait determinants include movements of the pelvic joint; therefore, an effective gait rehabilitation robot is expected to be capable of controlling the movements of the human pelvis. We present the design, implementation, control, and experimental verification of AssistOn-Gait, a robot-assisted trainer, for restoration and improvement of gait and balance of patients with disabilities affecting their lower extremities. In addition to overground gait and balance training, AssistOn-Gait can deliver pelvis-hip exercises aimed to correct compensatory movements arising from abnormal gait patterns, extending the type of therapies that can be administered using lower extremity exoskeletons. AssistOn-Gait features a modular design, consisting of an impedance controlled, self-aligning pelvis-hip exoskeleton, supported by a motion controlled holonomic mobile platform and a series-elastic body weight support system. The pelvis-hip exoskeleton possesses 7 active degrees of freedom to independently control the rotation of the each hip in the sagittal plane along with the pelvic rotation, the pelvic tilt, lateral pelvic displacement, and the pelvic displacements in the sagittal plane. The series elastic body weight support system can provide dynamic unloading to support a percentage of a patient's weight, while also compensating for the inertial forces caused by the vertical movements of the body. The holonomic mobile base can track the movements of patients on flat surfaces, allowing patients to walk naturally, start/stop motion, vary their speed, sidestep to maintain balance, and turn to change their walking direction. Each of these modules can be used independently or in combination with each other, to provide different configurations for overground and treadmill based training with and without dynamic body weight support. The pelvis-hip exoskeleton of AssistOn-Gait is constructed using two passively backdrivable planar parallel mechanisms connected to the patient with a custom harness, to enable both passive movements and independent active impedance control of the pelvis-hip complex. Furthermore, the exoskeleton is self-aligning; it can automatically adjust the center of rotation of its joint axes, enabling an ideal match between patient's hip rotation axes and the device axes in the sagittal plane. This feature not only guarantees ergonomy and comfort throughout the therapy, but also extends the usable range of motion for the hip joint. Moreover, this feature significantly shortens the setup time required to attach the patient to the exoskeleton. The exoskeleton can also be used to implement virtual constraints to ensure coordination and synchronization between various degrees of freedom of the pelvis-hip complex and to assist patients as-needed for natural gait cycles. The overall kinematics of AssistOn-Gait is redundant, as the exoskeleton module spans all the degrees of freedom covered by the mobile platform. Furthermore, the device features dual layer actuation, since the exoskeleton module is designed for force control with good transparency, while the mobile base is designed for motion control to carry the weight of the patient and the exoskeleton. The kinematically redundant dual layer actuation enables the mobile base of the system to be controlled using workspace centering control strategy without the need for any additional sensors, since the patient movements are readily measured by the exoskeleton module. The workspace centering controller ensures that the workspace limits of the exoskeleton module are not reached, decoupling the dynamics of the mobile base from the dynamics of the exoskeleton. Consequently, AssistOn-Gait possesses virtually unlimited workspace, while featuring the same output impedance and force rendering performance as its exoskeleton module. The mobile platform can also be used to generate virtual fixtures to guide patient movements. The ergonomy and useability of AssistOn-Gait have been tested with several human subject experiments. The experimental results verify that AssistOn-Gait can achieve the desired level of ergonomy and passive backdrivability, as the gait patterns with the device in zero impedance mode are shown not to significantly deviate from the natural gait of the subjects. Furthermore, virtual constraints and force-feedback assistance provided by AssistOn-Gait have been shown to be adequate to ensure repeatability of desired corrective gait patterns
ASSISTIVE DEVICE FOR LOWER EXTREMITY GAIT TRAINING AND ASSISTANCE
Ph.DDOCTOR OF PHILOSOPH
Joint Trajectory Generation and High-level Control for Patient-tailored Robotic Gait Rehabilitation
This dissertation presents a group of novel methods for robot-based gait rehabilitation which were developed aiming to offer more individualized therapies based on the specific condition of each patient, as well as to improve the overall rehabilitation experience for both patient and therapist. A novel methodology for gait pattern generation is proposed, which offers estimated hip and knee joint trajectories corresponding to healthy walking, and allows the therapist to graphically adapt the reference trajectories in order to fit better the patient's needs and disabilities. Additionally, the motion controllers for the hip and knee joints, mobile platform, and pelvic mechanism of an over-ground gait rehabilitation robotic system are also presented, as well as some proposed methods for assist as needed therapy. Two robot-patient synchronization approaches are also included in this work, together with a novel algorithm for online hip trajectory adaptation developed to reduce obstructive forces applied to the patient during therapy with compliant robotic systems. Finally, a prototype graphical user interface for the therapist is also presented
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