Representing Crowd Knowledge: Guidelines for Conceptual Modeling of User-generated Content

Organizations’ increasing reliance on externally produced information, such as online user-generated content (UGC) and crowdsourcing, challenges common assumptions about conceptual modeling in information systems (IS) development. We demonstrate UGC’s societal importance, analyze its distinguishing characteristics, identify specific conceptual modeling challenges in this setting, evaluate traditional and recently proposed approaches to modeling UGC, propose a set of conceptual modeling guidelines for developing IS that harness structured UGC, and demonstrate how to implement and evaluate the proposed guidelines using a case of development of a real crowdsourcing (citizen science) IS. We conclude by considering implications for conceptual modeling research and practice

Development and Validation of a Proof-of-Concept Prototype for Analytics-based Malicious Cybersecurity Insider Threat in a Real-Time Identification System

Insider threat has continued to be one of the most difficult cybersecurity threat vectors detectable by contemporary technologies. Most organizations apply standard technology-based practices to detect unusual network activity. While there have been significant advances in intrusion detection systems (IDS) as well as security incident and event management solutions (SIEM), these technologies fail to take into consideration the human aspects of personality and emotion in computer use and network activity, since insider threats are human-initiated. External influencers impact how an end-user interacts with both colleagues and organizational resources. Taking into consideration external influencers, such as personality, changes in organizational polices and structure, along with unusual technical activity analysis, would be an improvement over contemporary detection tools used for identifying at-risk employees. This would allow upper management or other organizational units to intervene before a malicious cybersecurity insider threat event occurs, or mitigate it quickly, once initiated. The main goal of this research study was to design, develop, and validate a proof-of-concept prototype for a malicious cybersecurity insider threat alerting system that will assist in the rapid detection and prediction of human-centric precursors to malicious cybersecurity insider threat activity. Disgruntled employees or end-users wishing to cause harm to the organization may do so by abusing the trust given to them in their access to available network and organizational resources. Reports on malicious insider threat actions indicated that insider threat attacks make up roughly 23% of all cybercrime incidents, resulting in $2.9 trillion in employee fraud losses globally. The damage and negative impact that insider threats cause was reported to be higher than that of outsider or other types of cybercrime incidents. Consequently, this study utilized weighted indicators to measure and correlate simulated user activity to possible precursors to malicious cybersecurity insider threat attacks. This study consisted of a mixed method approach utilizing an expert panel, developmental research, and quantitative data analysis using the developed tool on simulated data set. To assure validity and reliability of the indicators, a panel of subject matter experts (SMEs) reviewed the indicators and indicator categorizations that were collected from prior literature following the Delphi technique. The SMEs’ responses were incorporated into the development of a proof-of-concept prototype. Once the proof-of-concept prototype was completed and fully tested, an empirical simulation research study was conducted utilizing simulated user activity within a 16-month time frame. The results of the empirical simulation study were analyzed and presented. Recommendations resulting from the study also be provided

Mucosal immunology revisited through mass cytometry : from biology to bioinformatics and back

It is increasingly recognized that in order to gain further insights into human disorders and develop new therapeutic strategies and diagnostic tools, it is critical to have a comprehensive overview of immune cell subsets resident in tissues under physiological and pathological conditions. Flow cytometry has been the golden standard for analyzing immune cell subsets, and with a typical experiment, dozens of immune subsets can be discriminated. Due to the lack of spectrally-resolvable fluorochromes, mass cytometry utilizing metal-conjugated antibodies has shown to be a powerful tool for dissecting the immune landscape even further. Inflammatory intestinal diseases can only be understood by studying specialized cell types within the tissue niche itself. In this thesis, we applied mass cytometry and data-driven, automated analysis approaches to investigate the complex compositions of heterogeneous cell subsets, such as those encountered in intestinal biopsies. These types of data have the potential to greatly improve our understanding of human disease. In concert with clinical data, mass cytometry could enable a finer classification of patients and might aid in the development of improved diagnostics, prognostics and personalized therapeutic regimens. Fluidigm CorporationLUMC / Geneeskund

ICSEA 2022: the seventeenth international conference on software engineering advances

The Seventeenth International Conference on Software Engineering Advances (ICSEA 2022), held between October 16th and October 20th, 2022, continued a series of events covering a broad spectrum of software-related topics. The conference covered fundamentals on designing, implementing, testing, validating and maintaining various kinds of software. Several tracks were proposed to treat the topics from theory to practice, in terms of methodologies, design, implementation, testing, use cases, tools, and lessons learned. The conference topics covered classical and advanced methodologies, open source, agile software, as well as software deployment and software economics and education. Other advanced aspects are related to on-time practical aspects, such as run-time vulnerability checking, rejuvenation process, updates partial or temporary feature deprecation, software deployment and configuration, and on-line software updates. These aspects trigger implications related to patenting, licensing, engineering education, new ways for software adoption and improvement, and ultimately, to software knowledge management. There are many advanced applications requiring robust, safe, and secure software: disaster recovery applications, vehicular systems, biomedical-related software, biometrics related software, mission critical software, E-health related software, crisis-situation software. These applications require appropriate software engineering techniques, metrics and formalisms, such as, software reuse, appropriate software quality metrics, composition and integration, consistency checking, model checking, provers and reasoning. The nature of research in software varies slightly with the specific discipline researchers work in, yet there is much common ground and room for a sharing of best practice, frameworks, tools, languages and methodologies. Despite the number of experts we have available, little work is done at the meta level, that is examining how we go about our research, and how this process can be improved. There are questions related to the choice of programming language, IDEs and documentation styles and standard. Reuse can be of great benefit to research projects yet reuse of prior research projects introduces special problems that need to be mitigated. The research environment is a mix of creativity and systematic approach which leads to a creative tension that needs to be managed or at least monitored. Much of the coding in any university is undertaken by research students or young researchers. Issues of skills training, development and quality control can have significant effects on an entire department. In an industrial research setting, the environment is not quite that of industry as a whole, nor does it follow the pattern set by the university. The unique approaches and issues of industrial research may hold lessons for researchers in other domains. We take here the opportunity to warmly thank all the members of the ICSEA 2022 technical program committee, as well as all the reviewers. The creation of such a high-quality conference program would not have been possible without their involvement. We also kindly thank all the authors who dedicated much of their time and effort to contribute to ICSEA 2022. We truly believe that, thanks to all these efforts, the final conference program consisted of top-quality contributions. We also thank the members of the ICSEA 2022 organizing committee for their help in handling the logistics of this event. We hope that ICSEA 2022 was a successful international forum for the exchange of ideas and results between academia and industry and for the promotion of progress in software engineering advances

Turning the Board Blue: America\u27s Epiduralized System of Birth. A Medical Ethnography

This dissertation is a medical ethnography of a nurse-midwifery hospital-based maternity service in an urban American hospital. The research study incorporates on-site observation, interviews, and data collection. The recent transformation of American hospital childbirth is described. Epiduralized birth has become the norm, representing a standardization of the cascade of interventions so often referred to by critics of the system of hospital birth in the United States. The routine use of the epidural has led to a Gleichschaltung of birth where the centrality of the epidural makes necessary a unitary, complex, totalistic set of interventions all of which make up an entirety of interventions that cannot be separated from each other. The policy implications for this fundamental change in American birth are discussed. The history of childbirth and midwifery in the United States is also discussed as well as the culture of the profession of nurse-midwifery. The scientific literature regarding the physiology and ecology of birth, as well as the safety of medications used in epiduralized birth (particularly bupivacaine and pitocin) is analyzed. Finally, the closure of the maternity service observed throughout this ethnographic research is discussed in light of regionalization and centralization of childbirth

The Influence of Opinion Leaders towards the Purchase Intentions of Consumers in the Virtual Communities of Consumption

Tohoku University大滝精一課

Security Risk Management for the Internet of Things

In recent years, the rising complexity of Internet of Things (IoT) systems has increased their potential vulnerabilities and introduced new cybersecurity challenges. In this context, state of the art methods and technologies for security risk assessment have prominent limitations when it comes to large scale, cyber-physical and interconnected IoT systems. Risk assessments for modern IoT systems must be frequent, dynamic and driven by knowledge about both cyber and physical assets. Furthermore, they should be more proactive, more automated, and able to leverage information shared across IoT value chains. This book introduces a set of novel risk assessment techniques and their role in the IoT Security risk management process. Specifically, it presents architectures and platforms for end-to-end security, including their implementation based on the edge/fog computing paradigm. It also highlights machine learning techniques that boost the automation and proactiveness of IoT security risk assessments. Furthermore, blockchain solutions for open and transparent sharing of IoT security information across the supply chain are introduced. Frameworks for privacy awareness, along with technical measures that enable privacy risk assessment and boost GDPR compliance are also presented. Likewise, the book illustrates novel solutions for security certification of IoT systems, along with techniques for IoT security interoperability. In the coming years, IoT security will be a challenging, yet very exciting journey for IoT stakeholders, including security experts, consultants, security research organizations and IoT solution providers. The book provides knowledge and insights about where we stand on this journey. It also attempts to develop a vision for the future and to help readers start their IoT Security efforts on the right foot

Self-adaptation via concurrent multi-action evaluation for unknown context

Context-aware computing has been attracting growing attention in recent years. Generally, there are several ways for a context-aware system to select a course of action for a particular change of context. One way is for the system developers to encompass all possible context changes in the domain knowledge. Other methods include system inferences and adaptive learning whereby the system executes one action and evaluates the outcome and self-adapts/self-learns based on that. However, in situations where a system encounters unknown contexts, the iterative approach would become unfeasible when the size of the action space increases. Providing efficient solutions to this problem has been the main goal of this research project. Based on the developed abstract model, the designed methodology replaces the single action implementation and evaluation by multiple actions implemented and evaluated concurrently. This parallel evaluation of actions speeds up significantly the evolution time taken to select the best action suited to unknown context compared to the iterative approach. The designed and implemented framework efficiently carries out concurrent multi-action evaluation when an unknown context is encountered and finds the best course of action. Two concrete implementations of the framework were carried out demonstrating the usability and adaptability of the framework across multiple domains. The first implementation was in the domain of database performance tuning. The concrete implementation of the framework demonstrated the ability of concurrent multi-action evaluation technique to performance tune a database when performance is regressed for an unknown reason. The second implementation demonstrated the ability of the framework to correctly determine the threshold price to be used in a name-your-own-price channel when an unknown context is encountered. In conclusion the research introduced a new paradigm of a self-adaptation technique for context-aware application. Among the existing body of work, the concurrent multi-action evaluation is classified under the abstract concept of experiment-based self-adaptation techniques