Unpaired multi-modal segmentation via knowledge distillation

Multi-modal learning is typically performed with network architectures containing modality-specific layers and shared layers, utilizing co-registered images of different modalities. We propose a novel learning scheme for unpaired cross-modality image segmentation, with a highly compact architecture achieving superior segmentation accuracy. In our method, we heavily reuse network parameters, by sharing all convolutional kernels across CT and MRI, and only employ modality-specific internal normalization layers which compute respective statistics. To effectively train such a highly compact model, we introduce a novel loss term inspired by knowledge distillation, by explicitly constraining the KL-divergence of our derived prediction distributions between modalities. We have extensively validated our approach on two multi-class segmentation problems: i) cardiac structure segmentation, and ii) abdominal organ segmentation. Different network settings, i.e., 2D dilated network and 3D U-net, are utilized to investigate our method's general efficacy. Experimental results on both tasks demonstrate that our novel multi-modal learning scheme consistently outperforms single-modal training and previous multi-modal approaches

Towards Cross-modality Medical Image Segmentation with Online Mutual Knowledge Distillation

The success of deep convolutional neural networks is partially attributed to the massive amount of annotated training data. However, in practice, medical data annotations are usually expensive and time-consuming to be obtained. Considering multi-modality data with the same anatomic structures are widely available in clinic routine, in this paper, we aim to exploit the prior knowledge (e.g., shape priors) learned from one modality (aka., assistant modality) to improve the segmentation performance on another modality (aka., target modality) to make up annotation scarcity. To alleviate the learning difficulties caused by modality-specific appearance discrepancy, we first present an Image Alignment Module (IAM) to narrow the appearance gap between assistant and target modality data.We then propose a novel Mutual Knowledge Distillation (MKD) scheme to thoroughly exploit the modality-shared knowledge to facilitate the target-modality segmentation. To be specific, we formulate our framework as an integration of two individual segmentors. Each segmentor not only explicitly extracts one modality knowledge from corresponding annotations, but also implicitly explores another modality knowledge from its counterpart in mutual-guided manner. The ensemble of two segmentors would further integrate the knowledge from both modalities and generate reliable segmentation results on target modality. Experimental results on the public multi-class cardiac segmentation data, i.e., MMWHS 2017, show that our method achieves large improvements on CT segmentation by utilizing additional MRI data and outperforms other state-of-the-art multi-modality learning methods.Comment: Accepted by AAAI 202

LightVessel: Exploring Lightweight Coronary Artery Vessel Segmentation via Similarity Knowledge Distillation

In recent years, deep convolution neural networks (DCNNs) have achieved great prospects in coronary artery vessel segmentation. However, it is difficult to deploy complicated models in clinical scenarios since high-performance approaches have excessive parameters and high computation costs. To tackle this problem, we propose \textbf{LightVessel}, a Similarity Knowledge Distillation Framework, for lightweight coronary artery vessel segmentation. Primarily, we propose a Feature-wise Similarity Distillation (FSD) module for semantic-shift modeling. Specifically, we calculate the feature similarity between the symmetric layers from the encoder and decoder. Then the similarity is transferred as knowledge from a cumbersome teacher network to a non-trained lightweight student network. Meanwhile, for encouraging the student model to learn more pixel-wise semantic information, we introduce the Adversarial Similarity Distillation (ASD) module. Concretely, the ASD module aims to construct the spatial adversarial correlation between the annotation and prediction from the teacher and student models, respectively. Through the ASD module, the student model obtains fined-grained subtle edge segmented results of the coronary artery vessel. Extensive experiments conducted on Clinical Coronary Artery Vessel Dataset demonstrate that LightVessel outperforms various knowledge distillation counterparts.Comment: 5 pages, 7 figures, conferenc

Test-Time Adaptation for Nighttime Color-Thermal Semantic Segmentation

The ability to scene understanding in adverse visual conditions, e.g., nighttime, has sparked active research for RGB-Thermal (RGB-T) semantic segmentation. However, it is essentially hampered by two critical problems: 1) the day-night gap of RGB images is larger than that of thermal images, and 2) the class-wise performance of RGB images at night is not consistently higher or lower than that of thermal images. we propose the first test-time adaptation (TTA) framework, dubbed Night-TTA, to address the problems for nighttime RGBT semantic segmentation without access to the source (daytime) data during adaptation. Our method enjoys three key technical parts. Firstly, as one modality (e.g., RGB) suffers from a larger domain gap than that of the other (e.g., thermal), Imaging Heterogeneity Refinement (IHR) employs an interaction branch on the basis of RGB and thermal branches to prevent cross-modal discrepancy and performance degradation. Then, Class Aware Refinement (CAR) is introduced to obtain reliable ensemble logits based on pixel-level distribution aggregation of the three branches. In addition, we also design a specific learning scheme for our TTA framework, which enables the ensemble logits and three student logits to collaboratively learn to improve the quality of predictions during the testing phase of our Night TTA. Extensive experiments show that our method achieves state-of-the-art (SoTA) performance with a 13.07% boost in mIoU