5,369 research outputs found
Blur resolved OCT: full-range interferometric synthetic aperture microscopy through dispersion encoding
We present a computational method for full-range interferometric synthetic
aperture microscopy (ISAM) under dispersion encoding. With this, one can
effectively double the depth range of optical coherence tomography (OCT),
whilst dramatically enhancing the spatial resolution away from the focal plane.
To this end, we propose a model-based iterative reconstruction (MBIR) method,
where ISAM is directly considered in an optimization approach, and we make the
discovery that sparsity promoting regularization effectively recovers the
full-range signal. Within this work, we adopt an optimal nonuniform discrete
fast Fourier transform (NUFFT) implementation of ISAM, which is both fast and
numerically stable throughout iterations. We validate our method with several
complex samples, scanned with a commercial SD-OCT system with no hardware
modification. With this, we both demonstrate full-range ISAM imaging, and
significantly outperform combinations of existing methods.Comment: 17 pages, 7 figures. The images have been compressed for arxiv -
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An algorithm for constrained one-step inversion of spectral CT data
We develop a primal-dual algorithm that allows for one-step inversion of
spectral CT transmission photon counts data to a basis map decomposition. The
algorithm allows for image constraints to be enforced on the basis maps during
the inversion. The derivation of the algorithm makes use of a local upper
bounding quadratic approximation to generate descent steps for non-convex
spectral CT data discrepancy terms, combined with a new convex-concave
optimization algorithm. Convergence of the algorithm is demonstrated on
simulated spectral CT data. Simulations with noise and anthropomorphic phantoms
show examples of how to employ the constrained one-step algorithm for spectral
CT data.Comment: Submitted to Physics in Medicine and Biolog
Model based learning for accelerated, limited-view 3D photoacoustic tomography
Recent advances in deep learning for tomographic reconstructions have shown
great potential to create accurate and high quality images with a considerable
speed-up. In this work we present a deep neural network that is specifically
designed to provide high resolution 3D images from restricted photoacoustic
measurements. The network is designed to represent an iterative scheme and
incorporates gradient information of the data fit to compensate for limited
view artefacts. Due to the high complexity of the photoacoustic forward
operator, we separate training and computation of the gradient information. A
suitable prior for the desired image structures is learned as part of the
training. The resulting network is trained and tested on a set of segmented
vessels from lung CT scans and then applied to in-vivo photoacoustic
measurement data
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