The Parallelism Motifs of Genomic Data Analysis

Genomic data sets are growing dramatically as the cost of sequencing continues to decline and small sequencing devices become available. Enormous community databases store and share this data with the research community, but some of these genomic data analysis problems require large scale computational platforms to meet both the memory and computational requirements. These applications differ from scientific simulations that dominate the workload on high end parallel systems today and place different requirements on programming support, software libraries, and parallel architectural design. For example, they involve irregular communication patterns such as asynchronous updates to shared data structures. We consider several problems in high performance genomics analysis, including alignment, profiling, clustering, and assembly for both single genomes and metagenomes. We identify some of the common computational patterns or motifs that help inform parallelization strategies and compare our motifs to some of the established lists, arguing that at least two key patterns, sorting and hashing, are missing

Modular design of data-parallel graph algorithms

Amorphous Data Parallelism has proven to be a suitable vehicle for implementing concurrent graph algorithms effectively on multi-core architectures. In view of the growing complexity of graph algorithms for information analysis, there is a need to facilitate modular design techniques in the context of Amorphous Data Parallelism. In this paper, we investigate what it takes to formulate algorithms possessing Amorphous Data Parallelism in a modular fashion enabling a large degree of code re-use. Using the betweenness centrality algorithm, a widely popular algorithm in the analysis of social networks, we demonstrate that a single optimisation technique can suffice to enable a modular programming style without loosing the efficiency of a tailor-made monolithic implementation

Formal Representation of the SS-DB Benchmark and Experimental Evaluation in EXTASCID

Evaluating the performance of scientific data processing systems is a difficult task considering the plethora of application-specific solutions available in this landscape and the lack of a generally-accepted benchmark. The dual structure of scientific data coupled with the complex nature of processing complicate the evaluation procedure further. SS-DB is the first attempt to define a general benchmark for complex scientific processing over raw and derived data. It fails to draw sufficient attention though because of the ambiguous plain language specification and the extraordinary SciDB results. In this paper, we remedy the shortcomings of the original SS-DB specification by providing a formal representation in terms of ArrayQL algebra operators and ArrayQL/SciQL constructs. These are the first formal representations of the SS-DB benchmark. Starting from the formal representation, we give a reference implementation and present benchmark results in EXTASCID, a novel system for scientific data processing. EXTASCID is complete in providing native support both for array and relational data and extensible in executing any user code inside the system by the means of a configurable metaoperator. These features result in an order of magnitude improvement over SciDB at data loading, extracting derived data, and operations over derived data.Comment: 32 pages, 3 figure

Macroservers: An Execution Model for DRAM Processor-In-Memory Arrays

The emergence of semiconductor fabrication technology allowing a tight coupling between high-density DRAM and CMOS logic on the same chip has led to the important new class of Processor-In-Memory (PIM) architectures. Newer developments provide powerful parallel processing capabilities on the chip, exploiting the facility to load wide words in single memory accesses and supporting complex address manipulations in the memory. Furthermore, large arrays of PIMs can be arranged into a massively parallel architecture. In this report, we describe an object-based programming model based on the notion of a macroserver. Macroservers encapsulate a set of variables and methods; threads, spawned by the activation of methods, operate asynchronously on the variables' state space. Data distributions provide a mechanism for mapping large data structures across the memory region of a macroserver, while work distributions allow explicit control of bindings between threads and data. Both data and work distributuions are first-class objects of the model, supporting the dynamic management of data and threads in memory. This offers the flexibility required for fully exploiting the processing power and memory bandwidth of a PIM array, in particular for irregular and adaptive applications. Thread synchronization is based on atomic methods, condition variables, and futures. A special type of lightweight macroserver allows the formulation of flexible scheduling strategies for the access to resources, using a monitor-like mechanism