A scalable, portable, FPGA-based implementation of the Unscented Kalman Filter

Sustained technological progress has come to a point where robotic/autonomous systems may well soon become ubiquitous. In order for these systems to actually be useful, an increase in autonomous capability is necessary for aerospace, as well as other, applications. Greater aerospace autonomous capability means there is a need for high performance state estimation. However, the desire to reduce costs through simplified development processes and compact form factors can limit performance. A hardware-based approach, such as using a Field Programmable Gate Array (FPGA), is common when high performance is required, but hardware approaches tend to have a more complicated development process when compared to traditional software approaches; greater development complexity, in turn, results in higher costs. Leveraging the advantages of both hardware-based and software-based approaches, a hardware/software (HW/SW) codesign of the Unscented Kalman Filter (UKF), based on an FPGA, is presented. The UKF is split into an application-specific part, implemented in software to retain portability, and a non-application-specific part, implemented in hardware as a parameterisable IP core to increase performance. The codesign is split into three versions (Serial, Parallel and Pipeline) to provide flexibility when choosing the balance between resources and performance, allowing system designers to simplify the development process. Simulation results demonstrating two possible implementations of the design, a nanosatellite application and a Simultaneous Localisation and Mapping (SLAM) application, are presented. These results validate the performance of the HW/SW UKF and demonstrate its portability, particularly in small aerospace systems. Implementation (synthesis, timing, power) details for a variety of situations are presented and analysed to demonstrate how the HW/SW codesign can be scaled for any application

Image Processing and Analysis for Preclinical and Clinical Applications

Radiomics is one of the most successful branches of research in the field of image processing and analysis, as it provides valuable quantitative information for the personalized medicine. It has the potential to discover features of the disease that cannot be appreciated with the naked eye in both preclinical and clinical studies. In general, all quantitative approaches based on biomedical images, such as positron emission tomography (PET), computed tomography (CT) and magnetic resonance imaging (MRI), have a positive clinical impact in the detection of biological processes and diseases as well as in predicting response to treatment. This Special Issue, “Image Processing and Analysis for Preclinical and Clinical Applications”, addresses some gaps in this field to improve the quality of research in the clinical and preclinical environment. It consists of fourteen peer-reviewed papers covering a range of topics and applications related to biomedical image processing and analysis