1,165 research outputs found
Highly accurate model for prediction of lung nodule malignancy with CT scans
Computed tomography (CT) examinations are commonly used to predict lung
nodule malignancy in patients, which are shown to improve noninvasive early
diagnosis of lung cancer. It remains challenging for computational approaches
to achieve performance comparable to experienced radiologists. Here we present
NoduleX, a systematic approach to predict lung nodule malignancy from CT data,
based on deep learning convolutional neural networks (CNN). For training and
validation, we analyze >1000 lung nodules in images from the LIDC/IDRI cohort.
All nodules were identified and classified by four experienced thoracic
radiologists who participated in the LIDC project. NoduleX achieves high
accuracy for nodule malignancy classification, with an AUC of ~0.99. This is
commensurate with the analysis of the dataset by experienced radiologists. Our
approach, NoduleX, provides an effective framework for highly accurate nodule
malignancy prediction with the model trained on a large patient population. Our
results are replicable with software available at
http://bioinformatics.astate.edu/NoduleX
Autoencoder-based Image Recommendation for Lung Cancer Characterization
Neste projeto, temos como objetivo desenvolver um sistema de IA que recomende um conjunto de casos relativos (passados) para orientar a tomada de decisão do médico.
Objetivo: A ambição é desenvolver um modelo de aprendizado baseado em IA para caracterização de câncer de pulmão, a fim de auxiliar na rotina clínica. Considerando a complexidade dos fenômenos biológicos que ocorrem durante o desenvolvimento do câncer, as relações entre eles e as manifestações visuais capturadas pela tomografia computadorizada (CT) têm sido exploradas nos últimos anos. No entanto, devido à falta de robustez dos métodos atuais de aprendizado profundo, essas correlações são frequentemente consideradas espúrias e se perdem quando confrontadas com dados coletados a partir de distribuições alteradas: diferentes instituições, características demográficas ou até mesmo estágios de desenvolvimento do câncer.In this project, we aim to develop an AI system that recommends a set of relative (past) cases to guide the decision-making of the clinician.
Objective: The ambition is to develop an AI-based learning model for lung cancer characterization in order to assist in clinical routine. Considering the complexity of the biological phenomenat hat occur during cancer development, relationships between these and visual manifestations captured by CT have been explored in recent years; however, given the lack of robustness of current deep learning methods, these correlations are often found spurious and get lost when facing data collected from shifted distributions: different institutions, demographics or even stages of cancer development
Prototypes for Content-Based Image Retrieval in Clinical Practice
Content-based image retrieval (CBIR) has been proposed as key technology for computer-aided diagnostics (CAD). This paper reviews the state of the art and future challenges in CBIR for CAD applied to clinical practice
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