Gene Expression and its Discontents: Developmental disorders as dysfunctions of epigenetic cognition

Systems biology presently suffers the same mereological and sufficiency fallacies that haunt neural network models of high order cognition. Shifting perspective from the massively parallel space of gene matrix interactions to the grammar/syntax of the time series of expressed phenotypes using a cognitive paradigm permits import of techniques from statistical physics via the homology between information source uncertainty and free energy density. This produces a broad spectrum of possible statistical models of development and its pathologies in which epigenetic regulation and the effects of embedding environment are analogous to a tunable enzyme catalyst. A cognitive paradigm naturally incorporates memory, leading directly to models of epigenetic inheritance, as affected by environmental exposures, in the largest sense. Understanding gene expression, development, and their dysfunctions will require data analysis tools considerably more sophisticated than the present crop of simplistic models abducted from neural network studies or stochastic chemical reaction theory

Learning Material-Aware Local Descriptors for 3D Shapes

Material understanding is critical for design, geometric modeling, and analysis of functional objects. We enable material-aware 3D shape analysis by employing a projective convolutional neural network architecture to learn material- aware descriptors from view-based representations of 3D points for point-wise material classification or material- aware retrieval. Unfortunately, only a small fraction of shapes in 3D repositories are labeled with physical mate- rials, posing a challenge for learning methods. To address this challenge, we crowdsource a dataset of 3080 3D shapes with part-wise material labels. We focus on furniture models which exhibit interesting structure and material variabil- ity. In addition, we also contribute a high-quality expert- labeled benchmark of 115 shapes from Herman-Miller and IKEA for evaluation. We further apply a mesh-aware con- ditional random field, which incorporates rotational and reflective symmetries, to smooth our local material predic- tions across neighboring surface patches. We demonstrate the effectiveness of our learned descriptors for automatic texturing, material-aware retrieval, and physical simulation. The dataset and code will be publicly available.Comment: 3DV 201

An Empirical Evaluation of Deep Learning on Highway Driving

Numerous groups have applied a variety of deep learning techniques to computer vision problems in highway perception scenarios. In this paper, we presented a number of empirical evaluations of recent deep learning advances. Computer vision, combined with deep learning, has the potential to bring about a relatively inexpensive, robust solution to autonomous driving. To prepare deep learning for industry uptake and practical applications, neural networks will require large data sets that represent all possible driving environments and scenarios. We collect a large data set of highway data and apply deep learning and computer vision algorithms to problems such as car and lane detection. We show how existing convolutional neural networks (CNNs) can be used to perform lane and vehicle detection while running at frame rates required for a real-time system. Our results lend credence to the hypothesis that deep learning holds promise for autonomous driving.Comment: Added a video for lane detectio