An Improved Binary Grey-Wolf Optimizer with Simulated Annealing for Feature Selection

This paper proposes improvements to the binary grey-wolf optimizer (BGWO) to solve the feature selection (FS) problem associated with high data dimensionality, irrelevant, noisy, and redundant data that will then allow machine learning algorithms to attain better classification/clustering accuracy in less training time. We propose three variants of BGWO in addition to the standard variant, applying different transfer functions to tackle the FS problem. Because BGWO generates continuous values and FS needs discrete values, a number of V-shaped, S-shaped, and U-shaped transfer functions were investigated for incorporation with BGWO to convert their continuous values to binary. After investigation, we note that the performance of BGWO is affected by the selection of the transfer function. Then, in the first variant, we look to reduce the local minima problem by integrating an exploration capability to update the position of the grey wolf randomly within the search space with a certain probability; this variant was abbreviated as IBGWO. Consequently, a novel mutation strategy is proposed to select a number of the worst grey wolves in the population which are updated toward the best solution and randomly within the search space based on a certain probability to determine if the update is either toward the best or randomly. The number of the worst grey wolf selected by this strategy is linearly increased with the iteration. Finally, this strategy is combined with IBGWO to produce the second variant of BGWO that was abbreviated as LIBGWO. In the last variant, simulated annealing (SA) was integrated with LIBGWO to search around the best-so-far solution at the end of each iteration in order to identify better solutions. The performance of the proposed variants was validated on 32 datasets taken from the UCI repository and compared with six wrapper feature selection methods. The experiments show the superiority of the proposed improved variants in producing better classification accuracy than the other selected wrapper feature selection algorithms

Machine Learning and Integrative Analysis of Biomedical Big Data.

Recent developments in high-throughput technologies have accelerated the accumulation of massive amounts of omics data from multiple sources: genome, epigenome, transcriptome, proteome, metabolome, etc. Traditionally, data from each source (e.g., genome) is analyzed in isolation using statistical and machine learning (ML) methods. Integrative analysis of multi-omics and clinical data is key to new biomedical discoveries and advancements in precision medicine. However, data integration poses new computational challenges as well as exacerbates the ones associated with single-omics studies. Specialized computational approaches are required to effectively and efficiently perform integrative analysis of biomedical data acquired from diverse modalities. In this review, we discuss state-of-the-art ML-based approaches for tackling five specific computational challenges associated with integrative analysis: curse of dimensionality, data heterogeneity, missing data, class imbalance and scalability issues

Stable Feature Selection for Biomarker Discovery

Feature selection techniques have been used as the workhorse in biomarker discovery applications for a long time. Surprisingly, the stability of feature selection with respect to sampling variations has long been under-considered. It is only until recently that this issue has received more and more attention. In this article, we review existing stable feature selection methods for biomarker discovery using a generic hierarchal framework. We have two objectives: (1) providing an overview on this new yet fast growing topic for a convenient reference; (2) categorizing existing methods under an expandable framework for future research and development

Clustering analysis of railway driving missions with niching

A wide number of applications requires classifying or grouping data into a set of categories or clusters. Most popular clustering techniques to achieve this objective are K-means clustering and hierarchical clustering. However, both of these methods necessitate the a priori setting of the cluster number. In this paper, a clustering method based on the use of a niching genetic algorithm is presented, with the aim of finding the best compromise between the inter-cluster distance maximization and the intra-cluster distance minimization. This method is applied to three clustering benchmarks and to the classification of driving missions for railway applications

On the role of pre and post-processing in environmental data mining

The quality of discovered knowledge is highly depending on data quality. Unfortunately real data use to contain noise, uncertainty, errors, redundancies or even irrelevant information. The more complex is the reality to be analyzed, the higher the risk of getting low quality data. Knowledge Discovery from Databases (KDD) offers a global framework to prepare data in the right form to perform correct analyses. On the other hand, the quality of decisions taken upon KDD results, depend not only on the quality of the results themselves, but on the capacity of the system to communicate those results in an understandable form. Environmental systems are particularly complex and environmental users particularly require clarity in their results. In this paper some details about how this can be achieved are provided. The role of the pre and post processing in the whole process of Knowledge Discovery in environmental systems is discussed

Automated Big Text Security Classification

In recent years, traditional cybersecurity safeguards have proven ineffective against insider threats. Famous cases of sensitive information leaks caused by insiders, including the WikiLeaks release of diplomatic cables and the Edward Snowden incident, have greatly harmed the U.S. government's relationship with other governments and with its own citizens. Data Leak Prevention (DLP) is a solution for detecting and preventing information leaks from within an organization's network. However, state-of-art DLP detection models are only able to detect very limited types of sensitive information, and research in the field has been hindered due to the lack of available sensitive texts. Many researchers have focused on document-based detection with artificially labeled "confidential documents" for which security labels are assigned to the entire document, when in reality only a portion of the document is sensitive. This type of whole-document based security labeling increases the chances of preventing authorized users from accessing non-sensitive information within sensitive documents. In this paper, we introduce Automated Classification Enabled by Security Similarity (ACESS), a new and innovative detection model that penetrates the complexity of big text security classification/detection. To analyze the ACESS system, we constructed a novel dataset, containing formerly classified paragraphs from diplomatic cables made public by the WikiLeaks organization. To our knowledge this paper is the first to analyze a dataset that contains actual formerly sensitive information annotated at paragraph granularity.Comment: Pre-print of Best Paper Award IEEE Intelligence and Security Informatics (ISI) 2016 Manuscrip