13,398 research outputs found
Computerized Analysis of Magnetic Resonance Images to Study Cerebral Anatomy in Developing Neonates
The study of cerebral anatomy in developing neonates is of great importance for
the understanding of brain development during the early period of life. This
dissertation therefore focuses on three challenges in the modelling of cerebral
anatomy in neonates during brain development. The methods that have been
developed all use Magnetic Resonance Images (MRI) as source data.
To facilitate study of vascular development in the neonatal period, a set of image
analysis algorithms are developed to automatically extract and model cerebral
vessel trees. The whole process consists of cerebral vessel tracking from
automatically placed seed points, vessel tree generation, and vasculature
registration and matching. These algorithms have been tested on clinical Time-of-
Flight (TOF) MR angiographic datasets.
To facilitate study of the neonatal cortex a complete cerebral cortex segmentation
and reconstruction pipeline has been developed. Segmentation of the neonatal
cortex is not effectively done by existing algorithms designed for the adult brain
because the contrast between grey and white matter is reversed. This causes pixels
containing tissue mixtures to be incorrectly labelled by conventional methods. The
neonatal cortical segmentation method that has been developed is based on a novel
expectation-maximization (EM) method with explicit correction for mislabelled
partial volume voxels. Based on the resulting cortical segmentation, an implicit
surface evolution technique is adopted for the reconstruction of the cortex in
neonates. The performance of the method is investigated by performing a detailed
landmark study.
To facilitate study of cortical development, a cortical surface registration algorithm
for aligning the cortical surface is developed. The method first inflates extracted
cortical surfaces and then performs a non-rigid surface registration using free-form
deformations (FFDs) to remove residual alignment. Validation experiments using
data labelled by an expert observer demonstrate that the method can capture local
changes and follow the growth of specific sulcus
Segmentation and Restoration of Images on Surfaces by Parametric Active Contours with Topology Changes
In this article, a new method for segmentation and restoration of images on
two-dimensional surfaces is given. Active contour models for image segmentation
are extended to images on surfaces. The evolving curves on the surfaces are
mathematically described using a parametric approach. For image restoration, a
diffusion equation with Neumann boundary conditions is solved in a
postprocessing step in the individual regions. Numerical schemes are presented
which allow to efficiently compute segmentations and denoised versions of
images on surfaces. Also topology changes of the evolving curves are detected
and performed using a fast sub-routine. Finally, several experiments are
presented where the developed methods are applied on different artificial and
real images defined on different surfaces
Segmentation of ultrasound images of thyroid nodule for assisting fine needle aspiration cytology
The incidence of thyroid nodule is very high and generally increases with the
age. Thyroid nodule may presage the emergence of thyroid cancer. The thyroid
nodule can be completely cured if detected early. Fine needle aspiration
cytology is a recognized early diagnosis method of thyroid nodule. There are
still some limitations in the fine needle aspiration cytology, and the
ultrasound diagnosis of thyroid nodule has become the first choice for
auxiliary examination of thyroid nodular disease. If we could combine medical
imaging technology and fine needle aspiration cytology, the diagnostic rate of
thyroid nodule would be improved significantly. The properties of ultrasound
will degrade the image quality, which makes it difficult to recognize the edges
for physicians. Image segmentation technique based on graph theory has become a
research hotspot at present. Normalized cut (Ncut) is a representative one,
which is suitable for segmentation of feature parts of medical image. However,
how to solve the normalized cut has become a problem, which needs large memory
capacity and heavy calculation of weight matrix. It always generates over
segmentation or less segmentation which leads to inaccurate in the
segmentation. The speckle noise in B ultrasound image of thyroid tumor makes
the quality of the image deteriorate. In the light of this characteristic, we
combine the anisotropic diffusion model with the normalized cut in this paper.
After the enhancement of anisotropic diffusion model, it removes the noise in
the B ultrasound image while preserves the important edges and local details.
This reduces the amount of computation in constructing the weight matrix of the
improved normalized cut and improves the accuracy of the final segmentation
results. The feasibility of the method is proved by the experimental results.Comment: 15pages,13figure
WPU-Net: Boundary Learning by Using Weighted Propagation in Convolution Network
Deep learning has driven a great progress in natural and biological image
processing. However, in material science and engineering, there are often some
flaws and indistinctions in material microscopic images induced from complex
sample preparation, even due to the material itself, hindering the detection of
target objects. In this work, we propose WPU-net that redesigns the
architecture and weighted loss of U-Net, which forces the network to integrate
information from adjacent slices and pays more attention to the topology in
boundary detection task. Then, the WPU-net is applied into a typical material
example, i.e., the grain boundary detection of polycrystalline material.
Experiments demonstrate that the proposed method achieves promising performance
and outperforms state-of-the-art methods. Besides, we propose a new method for
object tracking between adjacent slices, which can effectively reconstruct 3D
structure of the whole material. Finally, we present a material microscopic
image dataset with the goal of advancing the state-of-the-art in image
processing for material science.Comment: technical repor
A graph-based mathematical morphology reader
This survey paper aims at providing a "literary" anthology of mathematical
morphology on graphs. It describes in the English language many ideas stemming
from a large number of different papers, hence providing a unified view of an
active and diverse field of research
Medical imaging analysis with artificial neural networks
Given that neural networks have been widely reported in the research community of medical imaging, we provide a focused literature survey on recent neural network developments in computer-aided diagnosis, medical image segmentation and edge detection towards visual content analysis, and medical image registration for its pre-processing and post-processing, with the aims of increasing awareness of how neural networks can be applied to these areas and to provide a foundation for further research and practical development. Representative techniques and algorithms are explained in detail to provide inspiring examples illustrating: (i) how a known neural network with fixed structure and training procedure could be applied to resolve a medical imaging problem; (ii) how medical images could be analysed, processed, and characterised by neural networks; and (iii) how neural networks could be expanded further to resolve problems relevant to medical imaging. In the concluding section, a highlight of comparisons among many neural network applications is included to provide a global view on computational intelligence with neural networks in medical imaging
A Novel Active Contour Model for Texture Segmentation
Texture is intuitively defined as a repeated arrangement of a basic pattern
or object in an image. There is no mathematical definition of a texture though.
The human visual system is able to identify and segment different textures in a
given image. Automating this task for a computer is far from trivial. There are
three major components of any texture segmentation algorithm: (a) The features
used to represent a texture, (b) the metric induced on this representation
space and (c) the clustering algorithm that runs over these features in order
to segment a given image into different textures. In this paper, we propose an
active contour based novel unsupervised algorithm for texture segmentation. We
use intensity covariance matrices of regions as the defining feature of
textures and find regions that have the most inter-region dissimilar covariance
matrices using active contours. Since covariance matrices are symmetric
positive definite, we use geodesic distance defined on the manifold of
symmetric positive definite matrices PD(n) as a measure of dissimlarity between
such matrices. We demonstrate performance of our algorithm on both artificial
and real texture images
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