872 research outputs found
The Importance of Forgetting: Limiting Memory Improves Recovery of Topological Characteristics from Neural Data
We develop of a line of work initiated by Curto and Itskov towards
understanding the amount of information contained in the spike trains of
hippocampal place cells via topology considerations. Previously, it was
established that simply knowing which groups of place cells fire together in an
animal's hippocampus is sufficient to extract the global topology of the
animal's physical environment. We model a system where collections of place
cells group and ungroup according to short-term plasticity rules. In
particular, we obtain the surprising result that in experiments with spurious
firing, the accuracy of the extracted topological information decreases with
the persistence (beyond a certain regime) of the cell groups. This suggests
that synaptic transience, or forgetting, is a mechanism by which the brain
counteracts the effects of spurious place cell activity
Computational Topology Techniques for Characterizing Time-Series Data
Topological data analysis (TDA), while abstract, allows a characterization of
time-series data obtained from nonlinear and complex dynamical systems. Though
it is surprising that such an abstract measure of structure - counting pieces
and holes - could be useful for real-world data, TDA lets us compare different
systems, and even do membership testing or change-point detection. However, TDA
is computationally expensive and involves a number of free parameters. This
complexity can be obviated by coarse-graining, using a construct called the
witness complex. The parametric dependence gives rise to the concept of
persistent homology: how shape changes with scale. Its results allow us to
distinguish time-series data from different systems - e.g., the same note
played on different musical instruments.Comment: 12 pages, 6 Figures, 1 Table, The Sixteenth International Symposium
on Intelligent Data Analysis (IDA 2017
Mind the Gap: A Study in Global Development through Persistent Homology
The Gapminder project set out to use statistics to dispel simplistic notions
about global development. In the same spirit, we use persistent homology, a
technique from computational algebraic topology, to explore the relationship
between country development and geography. For each country, four indicators,
gross domestic product per capita; average life expectancy; infant mortality;
and gross national income per capita, were used to quantify the development.
Two analyses were performed. The first considers clusters of the countries
based on these indicators, and the second uncovers cycles in the data when
combined with geographic border structure. Our analysis is a multi-scale
approach that reveals similarities and connections among countries at a variety
of levels. We discover localized development patterns that are invisible in
standard statistical methods
Critical Transitions In a Model of a Genetic Regulatory System
We consider a model for substrate-depletion oscillations in genetic systems,
based on a stochastic differential equation with a slowly evolving external
signal. We show the existence of critical transitions in the system. We apply
two methods to numerically test the synthetic time series generated by the
system for early indicators of critical transitions: a detrended fluctuation
analysis method, and a novel method based on topological data analysis
(persistence diagrams).Comment: 19 pages, 8 figure
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