743 research outputs found
The 2010 UK Home Office âSexualisation of Young Peopleâ Review: a discursive policy analysis
This paper offers a discursive policy analysis of the 2010 UK Home Office Sexualisation of Young People Review, authored by Linda Papadopoulos (2010a). It will scrutinise the narrative presented by the text of the danger posed by cultural representations to healthy development, and trace the way that the text links this danger to catastrophic outcomes: child sexual abuse, exploitation and trafficking. Examining this narrative, the article will propose that the UK Review deploys spatial metaphors to naturalise a gendered account of childhood, sexuality and danger, evoking the creeping influence of a corrupting culture on a girl's most private self. The article will also demonstrate that this spatial narrative underpins the epistemological structure of the text â its separation of the primary from the secondary, the real from the artificial
Quantum Observables Algebras and Abstract Differential Geometry: The Topos-Theoretic Dynamics of Diagrams of Commutative Algebraic Localizations
We construct a sheaf-theoretic representation of quantum observables algebras
over a base category equipped with a Grothendieck topology, consisting of
epimorphic families of commutative observables algebras, playing the role of
local arithmetics in measurement situations. This construction makes possible
the adaptation of the methodology of Abstract Differential Geometry (ADG), a la
Mallios, in a topos-theoretic environment, and hence, the extension of the
"mechanism of differentials" in the quantum regime. The process of gluing
information, within diagrams of commutative algebraic localizations, generates
dynamics, involving the transition from the classical to the quantum regime,
formulated cohomologically in terms of a functorial quantum connection, and
subsequently, detected via the associated curvature of that connection.Comment: 81 pages, replaced by expanded published versio
The Riddle of Gravitation
There is no doubt that both the special and general theories of relativity
capture the imagination. The anti-intuitive properties of the special theory of
relativity and its deep philosophical implications, the bizzare and dazzling
predictions of the general theory of relativity: the curvature of spacetime,
the exotic characteristics of black holes, the bewildering prospects of
gravitational waves, the discovery of astronomical objects as quasers and
pulsers, the expansion and the (possible) recontraction of the universe..., are
all breathtaking phenomena. In this paper, we give a philosophical
non-technical treatment of both the special and the general theory of
relativity together with an exposition of some of the latest physical theories.
We then give an outline of an axiomatic approach to relativity theories due to
Andreka and Nemeti that throws light on the logical structure of both theories.
This is followed by an exposition of some of the bewildering results
established by Andreka and Nemeti concerning the foundations of mathematics
using the notion of relativistic computers. We next give a survey on the
meaning and philosophical implications of the the quantum theory and end the
paper by an imaginary debate between Einstein and Neils Bohr reflecting both
Einstein's and Bohr's philosophical views on the quantum world.
The paper is written in a somewhat untraditional manner; there are too many
footnotes. In order not to burden the reader with all the details, we have
collected the more advanced material the footnotes. We think that this makes
the paper easier to read and simpler to follow. The paper in full is adressed
more to experts.Comment: 40 pages, LaTeX-fil
Categorical Ontology of Complex Systems, Meta-Systems and Theory of Levels: The Emergence of Life, Human Consciousness and Society
Single cell interactomics in simpler organisms, as well as somatic cell interactomics in multicellular organisms, involve biomolecular interactions in complex signalling pathways that were recently represented in modular terms by quantum automata with âreversible behaviorâ representing normal cell cycling and division. Other implications of such quantum automata, modular modeling of signaling pathways and cell differentiation during development are in the fields of neural plasticity and brain development leading to quantum-weave dynamic patterns and specific molecular processes underlying extensive memory, learning, anticipation mechanisms and the emergence of human consciousness during the early brain development in children. Cell interactomics is here represented for the first time as a mixture of âclassicalâ states that determine molecular dynamics subject to Boltzmann statistics and âsteady-stateâ, metabolic (multi-stable) manifolds, together with âconfigurationâ spaces of metastable quantum states emerging from complex quantum dynamics of interacting networks of biomolecules, such as proteins and nucleic acids that are now collectively defined as quantum interactomics. On the other hand, the time dependent evolution over several generations of cancer cells --that are generally known to undergo frequent and extensive genetic mutations and, indeed, suffer genomic transformations at the chromosome level (such as extensive chromosomal aberrations found in many colon cancers)-- cannot be correctly represented in the âstandardâ terms of quantum automaton modules, as the normal somatic cells can. This significant difference at the cancer cell genomic level is therefore reflected in major changes in cancer cell interactomics often from one cancer cell âcycleâ to the next, and thus it requires substantial changes in the modeling strategies, mathematical tools and experimental designs aimed at understanding cancer mechanisms. Novel solutions to this important problem in carcinogenesis are proposed and experimental validation procedures are suggested. From a medical research and clinical standpoint, this approach has important consequences for addressing and preventing the development of cancer resistance to medical therapy in ongoing clinical trials involving stage III cancer patients, as well as improving the designs of future clinical trials for cancer treatments.\ud
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KEYWORDS: Emergence of Life and Human Consciousness;\ud
Proteomics; Artificial Intelligence; Complex Systems Dynamics; Quantum Automata models and Quantum Interactomics; quantum-weave dynamic patterns underlying human consciousness; specific molecular processes underlying extensive memory, learning, anticipation mechanisms and human consciousness; emergence of human consciousness during the early brain development in children; Cancer cell âcyclingâ; interacting networks of proteins and nucleic acids; genetic mutations and chromosomal aberrations in cancers, such as colon cancer; development of cancer resistance to therapy; ongoing clinical trials involving stage III cancer patientsâ possible improvements of the designs for future clinical trials and cancer treatments. \ud
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