Exploiting Latent Features of Text and Graphs

As the size and scope of online data continues to grow, new machine learning techniques become necessary to best capitalize on the wealth of available information. However, the models that help convert data into knowledge require nontrivial processes to make sense of large collections of text and massive online graphs. In both scenarios, modern machine learning pipelines produce embeddings --- semantically rich vectors of latent features --- to convert human constructs for machine understanding. In this dissertation we focus on information available within biomedical science, including human-written abstracts of scientific papers, as well as machine-generated graphs of biomedical entity relationships. We present the Moliere system, and our method for identifying new discoveries through the use of natural language processing and graph mining algorithms. We propose heuristically-based ranking criteria to augment Moliere, and leverage this ranking to identify a new gene-treatment target for HIV-associated Neurodegenerative Disorders. We additionally focus on the latent features of graphs, and propose a new bipartite graph embedding technique. Using our graph embedding, we advance the state-of-the-art in hypergraph partitioning quality. Having newfound intuition of graph embeddings, we present Agatha, a deep-learning approach to hypothesis generation. This system learns a data-driven ranking criteria derived from the embeddings of our large proposed biomedical semantic graph. To produce human-readable results, we additionally propose CBAG, a technique for conditional biomedical abstract generation

A Comprehensive Survey on Deep Graph Representation Learning

Graph representation learning aims to effectively encode high-dimensional sparse graph-structured data into low-dimensional dense vectors, which is a fundamental task that has been widely studied in a range of fields, including machine learning and data mining. Classic graph embedding methods follow the basic idea that the embedding vectors of interconnected nodes in the graph can still maintain a relatively close distance, thereby preserving the structural information between the nodes in the graph. However, this is sub-optimal due to: (i) traditional methods have limited model capacity which limits the learning performance; (ii) existing techniques typically rely on unsupervised learning strategies and fail to couple with the latest learning paradigms; (iii) representation learning and downstream tasks are dependent on each other which should be jointly enhanced. With the remarkable success of deep learning, deep graph representation learning has shown great potential and advantages over shallow (traditional) methods, there exist a large number of deep graph representation learning techniques have been proposed in the past decade, especially graph neural networks. In this survey, we conduct a comprehensive survey on current deep graph representation learning algorithms by proposing a new taxonomy of existing state-of-the-art literature. Specifically, we systematically summarize the essential components of graph representation learning and categorize existing approaches by the ways of graph neural network architectures and the most recent advanced learning paradigms. Moreover, this survey also provides the practical and promising applications of deep graph representation learning. Last but not least, we state new perspectives and suggest challenging directions which deserve further investigations in the future

Fouille de données de santé

Dans le domaine de la santé, les techniques d’analyse de données sont de plus en plus populaires et se révèlent même indispensables pour gérer les gros volumes de données produits pour un patient et par le patient. Deux thématiques seront abordées dans cette présentation d'HDR.La première porte sur la définition, la formalisation, l’implémentation et la validation de méthodes d’analyse permettant de décrire le contenu de bases de données médicales. Je me suis particulièrement intéressée aux données séquentielles. J’ai fait évoluer la classique notion de motif séquentiel pour y intégrer des composantes contextuelles, spatiales et sur l’ordre partiel des éléments composant les motifs. Ces nouvelles informations enrichissent la sémantique initiale de ces motifs.La seconde thématique se focalise sur l’analyse des productions et des interactions des patients au travers des médias sociaux. J’ai principalement travaillé sur des méthodes permettant d’analyser les productions narratives des patients selon leurs temporalités, leurs thématiques, les sentiments associés ou encore le rôle et la réputation du locuteur s’étant exprimé dans les messages

Adaptive Learning and Mining for Data Streams and Frequent Patterns

Aquesta tesi està dedicada al disseny d'algorismes de mineria de dades per fluxos de dades que evolucionen en el temps i per l'extracció d'arbres freqüents tancats. Primer ens ocupem de cadascuna d'aquestes tasques per separat i, a continuació, ens ocupem d'elles conjuntament, desenvolupant mètodes de classificació de fluxos de dades que contenen elements que són arbres. En el model de flux de dades, les dades arriben a gran velocitat, i els algorismes que els han de processar tenen limitacions estrictes de temps i espai. En la primera part d'aquesta tesi proposem i mostrem un marc per desenvolupar algorismes que aprenen de forma adaptativa dels fluxos de dades que canvien en el temps. Els nostres mètodes es basen en l'ús de mòduls detectors de canvi i estimadors en els llocs correctes. Proposem ADWIN, un algorisme de finestra lliscant adaptativa, per la detecció de canvi i manteniment d'estadístiques actualitzades, i proposem utilitzar-lo com a caixa negra substituint els comptadors en algorismes inicialment no dissenyats per a dades que varien en el temps. Com ADWIN té garanties teòriques de funcionament, això obre la possibilitat d'ampliar aquestes garanties als algorismes d'aprenentatge i de mineria de dades que l'usin. Provem la nostre metodologia amb diversos mètodes d'aprenentatge com el Naïve Bayes, partició, arbres de decisió i conjunt de classificadors. Construïm un marc experimental per fer mineria amb fluxos de dades que varien en el temps, basat en el programari MOA, similar al programari WEKA, de manera que sigui fàcil pels investigadors de realitzar-hi proves experimentals. Els arbres són grafs acíclics connectats i són estudiats com vincles en molts casos. En la segona part d'aquesta tesi, descrivim un estudi formal dels arbres des del punt de vista de mineria de dades basada en tancats. A més, presentem algorismes eficients per fer tests de subarbres i per fer mineria d'arbres freqüents tancats ordenats i no ordenats. S'inclou una anàlisi de l'extracció de regles d'associació de confiança plena dels conjunts d'arbres tancats, on hem trobat un fenomen interessant: les regles que la seva contrapart proposicional és no trivial, són sempre certes en els arbres a causa de la seva peculiar combinatòria. I finalment, usant aquests resultats en fluxos de dades evolutius i la mineria d'arbres tancats freqüents, hem presentat algorismes d'alt rendiment per fer mineria d'arbres freqüents tancats de manera adaptativa en fluxos de dades que evolucionen en el temps. Introduïm una metodologia general per identificar patrons tancats en un flux de dades, utilitzant la Teoria de Reticles de Galois. Usant aquesta metodologia, desenvolupem un algorisme incremental, un basat en finestra lliscant, i finalment un que troba arbres freqüents tancats de manera adaptativa en fluxos de dades. Finalment usem aquests mètodes per a desenvolupar mètodes de classificació per a fluxos de dades d'arbres.This thesis is devoted to the design of data mining algorithms for evolving data streams and for the extraction of closed frequent trees. First, we deal with each of these tasks separately, and then we deal with them together, developing classification methods for data streams containing items that are trees. In the data stream model, data arrive at high speed, and the algorithms that must process them have very strict constraints of space and time. In the first part of this thesis we propose and illustrate a framework for developing algorithms that can adaptively learn from data streams that change over time. Our methods are based on using change detectors and estimator modules at the right places. We propose an adaptive sliding window algorithm ADWIN for detecting change and keeping updated statistics from a data stream, and use it as a black-box in place or counters or accumulators in algorithms initially not designed for drifting data. Since ADWIN has rigorous performance guarantees, this opens the possibility of extending such guarantees to learning and mining algorithms. We test our methodology with several learning methods as Naïve Bayes, clustering, decision trees and ensemble methods. We build an experimental framework for data stream mining with concept drift, based on the MOA framework, similar to WEKA, so that it will be easy for researchers to run experimental data stream benchmarks. Trees are connected acyclic graphs and they are studied as link-based structures in many cases. In the second part of this thesis, we describe a rather formal study of trees from the point of view of closure-based mining. Moreover, we present efficient algorithms for subtree testing and for mining ordered and unordered frequent closed trees. We include an analysis of the extraction of association rules of full confidence out of the closed sets of trees, and we have found there an interesting phenomenon: rules whose propositional counterpart is nontrivial are, however, always implicitly true in trees due to the peculiar combinatorics of the structures. And finally, using these results on evolving data streams mining and closed frequent tree mining, we present high performance algorithms for mining closed unlabeled rooted trees adaptively from data streams that change over time. We introduce a general methodology to identify closed patterns in a data stream, using Galois Lattice Theory. Using this methodology, we then develop an incremental one, a sliding-window based one, and finally one that mines closed trees adaptively from data streams. We use these methods to develop classification methods for tree data streams.Postprint (published version

Topic modeling and hypergraph mining to analyze the EGC conference history

Prix du meilleur article - Session «défi»National audienceEach year the EGC conference gathers researchers and practitioners from the knowledge discovery and management domain to present their latest advances. This year’s edition features an open challenge that encourages participants to leverage the EGC rich anthology which spans from 2004 to 2015. The ultimate goal is to highlight the dynamics of the conference history and to try to get a glimpse of the coming years. In this context, we first describe our methodology for inferring latent topics that pervade this corpus using non-negative matrix factorization. Based on the discovered topics and other properties of the articles (e.g., authors, affiliations) we shed light on interesting facts on both the topical and collaborative structures of the EGC society. Secondly, we employ a hypergraph itemset extraction process to discover existent but latent relations between authors or between topics. We also propose topic-author and author-author recommendations with a content-based approach. Lastly, we describe a Web interface for browsing this collection of articles complemented with the discovered knowledge

Advances in Grid Computing

This book approaches the grid computing with a perspective on the latest achievements in the field, providing an insight into the current research trends and advances, and presenting a large range of innovative research papers. The topics covered in this book include resource and data management, grid architectures and development, and grid-enabled applications. New ideas employing heuristic methods from swarm intelligence or genetic algorithm and quantum encryption are considered in order to explain two main aspects of grid computing: resource management and data management. The book addresses also some aspects of grid computing that regard architecture and development, and includes a diverse range of applications for grid computing, including possible human grid computing system, simulation of the fusion reaction, ubiquitous healthcare service provisioning and complex water systems

Large bichromatic point sets admit empty monochromatic 4-gons

We consider a variation of a problem stated by Erd˝os and Szekeres in 1935 about the existence of a number fES(k) such that any set S of at least fES(k) points in general position in the plane has a subset of k points that are the vertices of a convex k-gon. In our setting the points of S are colored, and we say that a (not necessarily convex) spanned polygon is monochromatic if all its vertices have the same color. Moreover, a polygon is called empty if it does not contain any points of S in its interior. We show that any bichromatic set of n ≥ 5044 points in R2 in general position determines at least one empty, monochromatic quadrilateral (and thus linearly many).Postprint (published version