Energy performance forecasting of residential buildings using fuzzy approaches

The energy consumption used for domestic purposes in Europe is, to a considerable extent, due to heating and cooling. This energy is produced mostly by burning fossil fuels, which has a high negative environmental impact. The characteristics of a building are an important factor to determine the necessities of heating and cooling loads. Therefore, the study of the relevant characteristics of the buildings, regarding the heating and cooling needed to maintain comfortable indoor air conditions, could be very useful in order to design and construct energy-efficient buildings. In previous studies, different machine-learning approaches have been used to predict heating and cooling loads from the set of variables: relative compactness, surface area, wall area, roof area, overall height, orientation, glazing area and glazing area distribution. However, none of these methods are based on fuzzy logic. In this research, we study two fuzzy logic approaches, i.e., fuzzy inductive reasoning (FIR) and adaptive neuro fuzzy inference system (ANFIS), to deal with the same problem. Fuzzy approaches obtain very good results, outperforming all the methods described in previous studies except one. In this work, we also study the feature selection process of FIR methodology as a pre-processing tool to select the more relevant variables before the use of any predictive modelling methodology. It is proven that FIR feature selection provides interesting insights into the main building variables causally related to heating and cooling loads. This allows better decision making and design strategies, since accurate cooling and heating load estimations and correct identification of parameters that affect building energy demands are of high importance to optimize building designs and equipment specifications.Peer ReviewedPostprint (published version

Identification of the Isotherm Function in Chromatography Using CMA-ES

This paper deals with the identification of the flux for a system of conservation laws in the specific example of analytic chromatography. The fundamental equations of chromatographic process are highly non linear. The state-of-the-art Evolution Strategy, CMA-ES (the Covariance Matrix Adaptation Evolution Strategy), is used to identify the parameters of the so-called isotherm function. The approach was validated on different configurations of simulated data using either one, two or three components mixtures. CMA-ES is then applied to real data cases and its results are compared to those of a gradient-based strategy

Genome-wide inference of ancestral recombination graphs

The complex correlation structure of a collection of orthologous DNA sequences is uniquely captured by the "ancestral recombination graph" (ARG), a complete record of coalescence and recombination events in the history of the sample. However, existing methods for ARG inference are computationally intensive, highly approximate, or limited to small numbers of sequences, and, as a consequence, explicit ARG inference is rarely used in applied population genomics. Here, we introduce a new algorithm for ARG inference that is efficient enough to apply to dozens of complete mammalian genomes. The key idea of our approach is to sample an ARG of n chromosomes conditional on an ARG of n-1 chromosomes, an operation we call "threading." Using techniques based on hidden Markov models, we can perform this threading operation exactly, up to the assumptions of the sequentially Markov coalescent and a discretization of time. An extension allows for threading of subtrees instead of individual sequences. Repeated application of these threading operations results in highly efficient Markov chain Monte Carlo samplers for ARGs. We have implemented these methods in a computer program called ARGweaver. Experiments with simulated data indicate that ARGweaver converges rapidly to the true posterior distribution and is effective in recovering various features of the ARG for dozens of sequences generated under realistic parameters for human populations. In applications of ARGweaver to 54 human genome sequences from Complete Genomics, we find clear signatures of natural selection, including regions of unusually ancient ancestry associated with balancing selection and reductions in allele age in sites under directional selection. Preliminary results also indicate that our methods can be used to gain insight into complex features of human population structure, even with a noninformative prior distribution.Comment: 88 pages, 7 main figures, 22 supplementary figures. This version contains a substantially expanded genomic data analysi