Subclass Discriminant Analysis of Morphological and Textural Features for HEp-2 Staining Pattern Classification

Classifying HEp-2 fluorescence patterns in Indirect Immunofluorescence (IIF) HEp-2 cell imaging is important for the differential diagnosis of autoimmune diseases. The current technique, based on human visual inspection, is time-consuming, subjective and dependent on the operator's experience. Automating this process may be a solution to these limitations, making IIF faster and more reliable. This work proposes a classification approach based on Subclass Discriminant Analysis (SDA), a dimensionality reduction technique that provides an effective representation of the cells in the feature space, suitably coping with the high within-class variance typical of HEp-2 cell patterns. In order to generate an adequate characterization of the fluorescence patterns, we investigate the individual and combined contributions of several image attributes, showing that the integration of morphological, global and local textural features is the most suited for this purpose. The proposed approach provides an accuracy of the staining pattern classification of about 90%

Engineering Art Galleries

The Art Gallery Problem is one of the most well-known problems in Computational Geometry, with a rich history in the study of algorithms, complexity, and variants. Recently there has been a surge in experimental work on the problem. In this survey, we describe this work, show the chronology of developments, and compare current algorithms, including two unpublished versions, in an exhaustive experiment. Furthermore, we show what core algorithmic ingredients have led to recent successes

Recognizing Visibility Graphs of Polygons with Holes and Internal-External Visibility Graphs of Polygons

Visibility graph of a polygon corresponds to its internal diagonals and boundary edges. For each vertex on the boundary of the polygon, we have a vertex in this graph and if two vertices of the polygon see each other there is an edge between their corresponding vertices in the graph. Two vertices of a polygon see each other if and only if their connecting line segment completely lies inside the polygon, and they are externally visible if and only if this line segment completely lies outside the polygon. Recognizing visibility graphs is the problem of deciding whether there is a simple polygon whose visibility graph is isomorphic to a given input graph. This problem is well-known and well-studied, but yet widely open in geometric graphs and computational geometry. Existential Theory of the Reals is the complexity class of problems that can be reduced to the problem of deciding whether there exists a solution to a quantifier-free formula F(X1,X2,...,Xn), involving equalities and inequalities of real polynomials with real variables. The complete problems for this complexity class are called Existential Theory of the Reals Complete. In this paper we show that recognizing visibility graphs of polygons with holes is Existential Theory of the Reals Complete. Moreover, we show that recognizing visibility graphs of simple polygons when we have the internal and external visibility graphs, is also Existential Theory of the Reals Complete.Comment: Sumbitted to COCOON2018 Conferenc

Fuchsian differential equation for the perimeter generating function of three-choice polygons

Using a simple transfer matrix approach we have derived very long series expansions for the perimeter generating function of three-choice polygons. We find that all the terms in the generating function can be reproduced from a linear Fuchsian differential equation of order 8. We perform an analysis of the properties of the differential equation.Comment: 13 pages, 2 figures, talk presented in honour of X. Viennot at Seminaire Lotharengien, Lucelle, France, April 3-6 2005. Paper amended and sligtly expanded after refereein

Packing identical simple polygons is NP-hard

Given a small polygon S, a big simple polygon B and a positive integer k, it is shown to be NP-hard to determine whether k copies of the small polygon (allowing translation and rotation) can be placed in the big polygon without overlap. Previous NP-hardness results were only known in the case where the big polygon is allowed to be non-simple. A novel reduction from Planar-Circuit-SAT is presented where a small polygon is constructed to encode the entire circuit