3,194 research outputs found

    Making More Efficient the Dissemination of the Information in the Field of Anti-Aging through Information Technology

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    ICT have become extremely important because they allow everybody to participate at the Information Society, in spite of under-privileged personal or social situation. Health Education Informatics Systems (HEIS), as a method for facilitating the exchange of information between specialists, physicians and patients, or authorized organisations, become a necessary modern tool which offer quality solutions, a correct source of information and pertinent instrument for taking decisions. The members of the aging society must be motivated to have access through ICT at knowledge that can improve and prolong the active life. The dramatic demographic transformations of our century have imposed the reconsideration of the social policies and of the use of HEIS for disseminating the anti-aging information, for empowering the person regarding his own state of health, and also for the real involving of the elderly in using the Internet. AgingNice is a multidisciplinary complex system that belongs to the health informatics systems with particularization in the anti-aging domain and that allows the sharing of the knowledge concerning the specific research and the promotion of the theoretical and practical information, both among the stakeholders from the medical area and at the person level.anti-aging, elderly, ICT, health informatics systems, web services

    Diagnosis, monitoring and treatment of systemic lupus erythematosus: a systematic review of clinical practice guidelines.

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    Objectives: Management of SLE is complex and variability in practices exists. Guidelines have been developed to help improve the management of SLE patients but there has been no formal evaluation of these guidelines. This study aims to compare the scope, quality and consistency of clinical practice guidelines on the diagnosis, monitoring and treatment of patients with systemic lupus erythematosus (SLE). Methods: Electronic databases were searched up to April 2014. The Appraisal of Guidelines for Research and Evaluation (AGREE) II instrument and textual synthesis was used to appraise and compare recommendations. Results: Nine clinical practice guidelines and five consensus statements were identified, which covered seven topics: diagnosis, monitoring, treatment, neuropsychiatric SLE, lupus nephritis, anti-phospholipid syndrome and other manifestations of lupus. The methodological quality of the guidelines was variable, with the overall mean AGREE II scores ranging from 31% to 75% out of a maximum 100%. Scores were consistently low for applicability, with only one guideline scoring above 50%. There was substantial variability in the treatments recommended for class II and V lupus nephritis, the recommended duration of maintenance therapy for class III/IV lupus nephritis (from 1 to 4 years), and timing of ophthalmological examination for patients on corticosteroids. Conclusion: Published guidelines on SLE cover a complex area of clinical care but the methodological quality, scope and recommendations varied substantially. Collaborative and multidisciplinary efforts to develop comprehensive, high-quality evidence-based guidelines are needed to promote best treatment and health outcomes for patients with SLE.DT is funded by a postgraduate scholarship from the Sydney Medical School, The University of Sydney

    Open access week 2021 at the University of Eastern Finland Library

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    International Open Access Week is a global event that many institutions and organisations take part in annually. Often the libraries of academic institutions are eager to participate. The level of participation can vary from simply sharing knowledge about the week to, for example, organising events. In 2021, the University of Eastern Finland library decided to put more effort to the week than before, since it has a role as an active promoter of open science. Medical Subject Headings: Anniversaries and Special Events; Awards and Prizes; Blogging; Libraries; Open Access Publishin

    Selangor state structure plan (SSP) : a way forward to 2035

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    StateStructurePlan(SSP) is a document that prepare a planning framework that will guide and control the state’s physical development as required under the Town and Country Planing Act1976 (Act172). The study area is the Selangor State, located on the west coast of Peninsular Malaysia. This study adopts the process of state structure plan preparation in accordance to Plan Malaysia’s Manual. The development concept proposed in the plan is “Interdependent Polycentric Economic Region”, defined as economic corridor and growth centres that are depending on one and another. There are 5 development thrusts with 32 policies that are being proposed. From the policies, a total of 9 high impact projects being proposed for the state of Selangor

    The Korean Society for Neuro-Oncology (KSNO) Guideline for WHO Grade III Cerebral Gliomas in Adults: Version 2019.01

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    BACKGROUND: There was no practical guideline for the management of patients with central nervous system tumor in Korea in the past. Thus, the Korean Society for Neuro-Oncology (KSNO), a multidisciplinary academic society, developed the guideline for glioblastoma successfully and published it in Brain Tumor Research and Treatment, the official journal of KSNO, in April 2019. Recently, the KSNO guideline for World Health Organization (WHO) grade III cerebral glioma in adults has been established. METHODS: The Working Group was composed of 35 multidisciplinary medical experts in Korea. References were identified by searches in PubMed, MEDLINE, EMBASE, and Cochrane CENTRAL databases using specific and sensitive keywords as well as combinations of keywords. Scope of the disease was confined to cerebral anaplastic astrocytoma and oligodendroglioma in adults. RESULTS: Whenever radiological feature suggests high grade glioma, maximal safe resection if feasible is globally recommended. After molecular and histological examinations, patients with anaplastic astrocytoma, isocitrate dehydrogenase (IDH)-mutant should be primary treated by standard brain radiotherapy and adjuvant temozolomide chemotherapy whereas those with anaplastic astrocytoma, NOS, and anaplastic astrocytoma, IDH-wildtype should be treated following the protocol for glioblastomas. In terms of anaplastic oligodendroglioma, IDH-mutant and 1p19q-codeletion, and anaplastic oligodendroglioma, NOS should be primary treated by standard brain radiotherapy and neoadjuvant or adjuvant PCV (procarbazine, lomustine, and vincristine) combination chemotherapy. CONCLUSION: The KSNO's guideline recommends that WHO grade III cerebral glioma of adults should be treated by maximal safe resection if feasible, followed by radiotherapy and/or chemotherapy according to molecular and histological features of tumors.ope
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