Decorrelation of neural-network activity by inhibitory feedback

Correlations in spike-train ensembles can seriously impair the encoding of information by their spatio-temporal structure. An inevitable source of correlation in finite neural networks is common presynaptic input to pairs of neurons. Recent theoretical and experimental studies demonstrate that spike correlations in recurrent neural networks are considerably smaller than expected based on the amount of shared presynaptic input. By means of a linear network model and simulations of networks of leaky integrate-and-fire neurons, we show that shared-input correlations are efficiently suppressed by inhibitory feedback. To elucidate the effect of feedback, we compare the responses of the intact recurrent network and systems where the statistics of the feedback channel is perturbed. The suppression of spike-train correlations and population-rate fluctuations by inhibitory feedback can be observed both in purely inhibitory and in excitatory-inhibitory networks. The effect is fully understood by a linear theory and becomes already apparent at the macroscopic level of the population averaged activity. At the microscopic level, shared-input correlations are suppressed by spike-train correlations: In purely inhibitory networks, they are canceled by negative spike-train correlations. In excitatory-inhibitory networks, spike-train correlations are typically positive. Here, the suppression of input correlations is not a result of the mere existence of correlations between excitatory (E) and inhibitory (I) neurons, but a consequence of a particular structure of correlations among the three possible pairings (EE, EI, II)

Analysis of two-point statistics of cosmic shear: III. Covariances of shear measures made easy

In recent years cosmic shear, the weak gravitational lensing effect by the large-scale structure of the Universe, has proven to be one of the observational pillars on which the cosmological concordance model is founded. Several cosmic shear statistics have been developed in order to analyze data from surveys. For the covariances of the prevalent second-order measures we present simple and handy formulae, valid under the assumptions of Gaussian density fluctuations and a simple survey geometry. We also formulate these results in the context of shear tomography, i.e. the inclusion of redshift information, and generalize them to arbitrary data field geometries. We define estimators for the E- and B-mode projected power spectra and show them to be unbiased in the case of Gaussianity and a simple survey geometry. From the covariance of these estimators we demonstrate how to derive covariances of arbitrary combinations of second-order cosmic shear measures. We then recalculate the power spectrum covariance for general survey geometries and examine the bias thereby introduced on the estimators for exemplary configurations. Our results for the covariances are considerably simpler than and analytically shown to be equivalent to the real-space approach presented in the first paper of this series. We find good agreement with other numerical evaluations and confirm the general properties of the covariance matrices. The studies of the specific survey configurations suggest that our simplified covariances may be employed for realistic survey geometries to good approximation.Comment: 15 pages, including 4 figures (Fig. 3 reduced in quality); minor changes, Fig. 4 extended; published in A&

The azimuth structure of nuclear collisions -- I

We describe azimuth structure commonly associated with elliptic and directed flow in the context of 2D angular autocorrelations for the purpose of precise separation of so-called nonflow (mainly minijets) from flow. We extend the Fourier-transform description of azimuth structure to include power spectra and autocorrelations related by the Wiener-Khintchine theorem. We analyze several examples of conventional flow analysis in that context and question the relevance of reaction plane estimation to flow analysis. We introduce the 2D angular autocorrelation with examples from data analysis and describe a simulation exercise which demonstrates precise separation of flow and nonflow using the 2D autocorrelation method. We show that an alternative correlation measure based on Pearson's normalized covariance provides a more intuitive measure of azimuth structure.Comment: 27 pages, 12 figure

Effect of Ground Motion Characteristics on the Seismic Response of Torsionally Coupled Elastic Systems

This study presents a systematic investigation of the effects of ground motion characteristics, especially its multi-directional character, on the response of torsionally coupled elastic structural systems. The ground motion model is probabilistic and is founded on the assumption of the existence of ground motion principal directions. The structural systems considered are single-story and multi-story elastic shear beam models with stiffness eccentricity.National Science Foundation Grants ENV 77-07190 and PFR 80-0258

A unified view on weakly correlated recurrent networks

The diversity of neuron models used in contemporary theoretical neuroscience to investigate specific properties of covariances raises the question how these models relate to each other. In particular it is hard to distinguish between generic properties and peculiarities due to the abstracted model. Here we present a unified view on pairwise covariances in recurrent networks in the irregular regime. We consider the binary neuron model, the leaky integrate-and-fire model, and the Hawkes process. We show that linear approximation maps each of these models to either of two classes of linear rate models, including the Ornstein-Uhlenbeck process as a special case. The classes differ in the location of additive noise in the rate dynamics, which is on the output side for spiking models and on the input side for the binary model. Both classes allow closed form solutions for the covariance. For output noise it separates into an echo term and a term due to correlated input. The unified framework enables us to transfer results between models. For example, we generalize the binary model and the Hawkes process to the presence of conduction delays and simplify derivations for established results. Our approach is applicable to general network structures and suitable for population averages. The derived averages are exact for fixed out-degree network architectures and approximate for fixed in-degree. We demonstrate how taking into account fluctuations in the linearization procedure increases the accuracy of the effective theory and we explain the class dependent differences between covariances in the time and the frequency domain. Finally we show that the oscillatory instability emerging in networks of integrate-and-fire models with delayed inhibitory feedback is a model-invariant feature: the same structure of poles in the complex frequency plane determines the population power spectra