5,276 research outputs found

    Deep Learning in Cardiology

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    The medical field is creating large amount of data that physicians are unable to decipher and use efficiently. Moreover, rule-based expert systems are inefficient in solving complicated medical tasks or for creating insights using big data. Deep learning has emerged as a more accurate and effective technology in a wide range of medical problems such as diagnosis, prediction and intervention. Deep learning is a representation learning method that consists of layers that transform the data non-linearly, thus, revealing hierarchical relationships and structures. In this review we survey deep learning application papers that use structured data, signal and imaging modalities from cardiology. We discuss the advantages and limitations of applying deep learning in cardiology that also apply in medicine in general, while proposing certain directions as the most viable for clinical use.Comment: 27 pages, 2 figures, 10 table

    Focal Spot, Fall 1985

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    https://digitalcommons.wustl.edu/focal_spot_archives/1041/thumbnail.jp

    Fast and accurate classification of echocardiograms using deep learning

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    Echocardiography is essential to modern cardiology. However, human interpretation limits high throughput analysis, limiting echocardiography from reaching its full clinical and research potential for precision medicine. Deep learning is a cutting-edge machine-learning technique that has been useful in analyzing medical images but has not yet been widely applied to echocardiography, partly due to the complexity of echocardiograms' multi view, multi modality format. The essential first step toward comprehensive computer assisted echocardiographic interpretation is determining whether computers can learn to recognize standard views. To this end, we anonymized 834,267 transthoracic echocardiogram (TTE) images from 267 patients (20 to 96 years, 51 percent female, 26 percent obese) seen between 2000 and 2017 and labeled them according to standard views. Images covered a range of real world clinical variation. We built a multilayer convolutional neural network and used supervised learning to simultaneously classify 15 standard views. Eighty percent of data used was randomly chosen for training and 20 percent reserved for validation and testing on never seen echocardiograms. Using multiple images from each clip, the model classified among 12 video views with 97.8 percent overall test accuracy without overfitting. Even on single low resolution images, test accuracy among 15 views was 91.7 percent versus 70.2 to 83.5 percent for board-certified echocardiographers. Confusional matrices, occlusion experiments, and saliency mapping showed that the model finds recognizable similarities among related views and classifies using clinically relevant image features. In conclusion, deep neural networks can classify essential echocardiographic views simultaneously and with high accuracy. Our results provide a foundation for more complex deep learning assisted echocardiographic interpretation.Comment: 31 pages, 8 figure

    Models of information systems devoted to medical-imaging labs: an experience in the CNR clinical physiology institute

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    At the end of the 1990s, the SPERIGEST project, supported by the Italian Health Ministry, and fully developed at the Institute of Clinical Physiology, established an operative integrated clinical and healthcare information system. Continuously evolving and dynamically optimising procedures and protocols solve problems of: harmonisation of instrumentation of different brands; management of multimedia data provided by different medical imaging labs; satisfaction of both clinical and research needs; legal and economical requirements; user-friendship of the system. A ten years experience shows positive approach by medical and healthcare operators, coordinated activity, higher efficiency, simplified procedures, major concentration on medical decision-making

    Focal Spot, Fall/Winter 1999

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    https://digitalcommons.wustl.edu/focal_spot_archives/1083/thumbnail.jp

    Panel discussion: the role of macroeconomic policy

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    Macroeconomics

    Large-Scale Analysis of the Accuracy of the Journal Classification Systems of Web of Science and Scopus

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    Journal classification systems play an important role in bibliometric analyses. The two most important bibliographic databases, Web of Science and Scopus, each provide a journal classification system. However, no study has systematically investigated the accuracy of these classification systems. To examine and compare the accuracy of journal classification systems, we define two criteria on the basis of direct citation relations between journals and categories. We use Criterion I to select journals that have weak connections with their assigned categories, and we use Criterion II to identify journals that are not assigned to categories with which they have strong connections. If a journal satisfies either of the two criteria, we conclude that its assignment to categories may be questionable. Accordingly, we identify all journals with questionable classifications in Web of Science and Scopus. Furthermore, we perform a more in-depth analysis for the field of Library and Information Science to assess whether our proposed criteria are appropriate and whether they yield meaningful results. It turns out that according to our citation-based criteria Web of Science performs significantly better than Scopus in terms of the accuracy of its journal classification system

    The Research Space: using the career paths of scholars to predict the evolution of the research output of individuals, institutions, and nations

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    In recent years scholars have built maps of science by connecting the academic fields that cite each other, are cited together, or that cite a similar literature. But since scholars cannot always publish in the fields they cite, or that cite them, these science maps are only rough proxies for the potential of a scholar, organization, or country, to enter a new academic field. Here we use a large dataset of scholarly publications disambiguated at the individual level to create a map of science-or research space-where links connect pairs of fields based on the probability that an individual has published in both of them. We find that the research space is a significantly more accurate predictor of the fields that individuals and organizations will enter in the future than citation based science maps. At the country level, however, the research space and citations based science maps are equally accurate. These findings show that data on career trajectories-the set of fields that individuals have previously published in-provide more accurate predictors of future research output for more focalized units-such as individuals or organizations-than citation based science maps
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