371 research outputs found

    A Boolean based Question Answering System

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    The search engine searches the information according to the key words and provides users with related links, which need users to review and find the direct information among a large number of webpages. To avoid this drawback and improve the search results from search engine, we implemented a Boolean based Question Answering System. This system used Boolean Retrieval Model to analyze and match the text information from corresponding webpages in the document indexing step when users ask a Boolean expression based question. To evaluate system and analyze Boolean Retrieval Model, we used the data set from TREC (Text Retrieval Conference) to finish our experiment. Different Boolean operators in the questions such as AND, OR has been evaluated separately which is clear to analyze the effectiveness for each of them. We also evaluate the overall performance for this system

    New results on copulas and related concepts

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    Fuzzy expert systems in civil engineering

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    Imperial Users onl

    Neuro-fuzzy modeling of multi-field surface neuroprostheses for hand grasp

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    154 p.Las neuroprótesis aplican pulsos eléctricos a los nervios periféricos con el objetivo de sustituir funciones motrices/sensoriales perdidas, dando asistencia e influyendo positivamente en la rehabilitación motriz de personas con disfunciones motrices causadas por trastornos neurológicos. La complejidad de la neuroanatomía del antebrazo y la mano, su dimensionalidad, las diversas tareas no-cíclicas, la variabilidad de movimientos entre sujetos y la reducida selectividad de las neuroprótesis superficiales, ha dado lugar al diseño de un número reducido de neuroprótesis orientadas a agarres básicos. La posibilidad de hacer más selectiva la estimulación mediante los electrodos multi-campo, junto con el conocimiento sobre la incomodidad y los movimientos que genera la aplicación de la estimulación eléctrica funcional (FES por sus siglas en inglés) en miembro superior, podrían ser base fundamental para el desarrollo de neuroprótesis de agarre más avanzadas. La presente tesis describe un análisis de incomodidad como resultado de FES en el miembro superior, y propone modelos neuro-difusos para neuroprótesis de agarre tanto para personas sanas como para personas con trastornos neurológicos. El conocimiento generado respecto a la incomodidad puede ser utilizado como guía para desarrollar aplicaciones de FES de miembro superior más cómodas. Del mismo modo, los modelos propuestos en esta tesis pueden ser utilizados para apoyar el diseño y la validación de sistemas de control avanzados en neuroprótesis dirigidas a la función de agarre.Tecnalia; Intelligent Control Research Grou

    Nineteenth Annual Conference on Manual Control

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    A survey of the application of soft computing to investment and financial trading

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    Functional object-types as a foundation of complex knowledge-based systems

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    Kinetics of Multivalent Binding Processes

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    Multivalent bindings are a combination of several weaker bonds between two molecules such as a receptor and a ligand. Because the combined bonds are stronger than the individual ones, the molecules may interact longer. Thus, this concept is very interesting for targeted drug design. Theoretically, these bindings and unbindings are rare stochastic events. Literature on multivalency is vast, especially on specific experimental setups. However, there exists little theoretical studies for general n-valent settings. This thesis aims to fill that gap by modelling the binding process as kinetic rate matrices and applying the clustering algorithm PCCA+. While the binding and unbinding of the single ligand-receptor pairs happens on a fast time scale i.e. in the micro-perspective, the association or dissociation of a complex is acting on a slow timescale, thus in the macro-perspective. The existing kinITC method does not capture the switch between these time scales. Thus the method proposed in this thesis describes an alteration to kinITC, called kinITC+. The key findings of the thesis are: • It is possible to gain kinetic information from thermodynamic data. • The macroscopic binding rate kon is not constant, but ligand concentration dependent. • There is at least one counterexample to the assumption that the thermodynamic contribution of rebinding increases with valency
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