Improvement of P300-Based Brain-Computer Interfaces for Home Appliances Control by Data Balancing Techniques

The oddball paradigm used in P300-based brain-computer interfaces (BCIs) intrinsically poses the issue of data imbalance between target stimuli and nontarget stimuli. Data imbalance can cause overfitting problems and, consequently, poor classification performance. The purpose of this study is to improve BCI performance by solving this data imbalance problem with sampling techniques. The sampling techniques were applied to BCI data in 15 subjects controlling a door lock, 15 subjects an electric light, and 14 subjects a Bluetooth speaker. We explored two categories of sampling techniques: oversampling and undersampling. Oversampling techniques, including random oversampling, synthetic minority oversampling technique (SMOTE), borderline-SMOTE, support vector machine (SVM) SMOTE, and adaptive synthetic sampling, were used to increase the number of samples for the class of target stimuli. Undersampling techniques, including random undersampling, neighborhood cleaning rule, Tomek's links, and weighted undersampling bagging, were used to reduce the class size of nontarget stimuli. The over- or undersampled data were classified by an SVM classifier. Overall, some oversampling techniques improved BCI performance while undersampling techniques often degraded performance. Particularly, using borderline-SMOTE yielded the highest accuracy (87.27%) and information transfer rate (8.82 bpm) across all three appliances. Moreover, borderline-SMOTE led to performance improvement, especially for poor performers. A further analysis showed that borderline-SMOTE improved SVM by generating more support vectors within the target class and enlarging margins. However, there was no difference in the accuracy between borderline-SMOTE and the method of applying the weighted regularization parameter of the SVM. Our results suggest that although oversampling improves performance of P300-based BCIs, it is not just the effect of the oversampling techniques, but rather the effect of solving the data imbalance problem

A Lightweight Multi-Scale Convolutional Neural Network for P300 Decoding: Analysis of Training Strategies and Uncovering of Network Decision

Convolutional neural networks (CNNs), which automatically learn features from raw data to approximate functions, are being increasingly applied to the end-to-end analysis of electroencephalographic (EEG) signals, especially for decoding brain states in brain-computer interfaces (BCIs). Nevertheless, CNNs introduce a large number of trainable parameters, may require long training times, and lack in interpretability of learned features. The aim of this study is to propose a CNN design for P300 decoding with emphasis on its lightweight design while guaranteeing high performance, on the effects of different training strategies, and on the use of post-hoc techniques to explain network decisions. The proposed design, named MS-EEGNet, learned temporal features in two different timescales (i.e., multi-scale, MS) in an efficient and optimized (in terms of trainable parameters) way, and was validated on three P300 datasets. The CNN was trained using different strategies (within-participant and within-session, within-participant and cross-session, leave-one-subject-out, transfer learning) and was compared with several state-of-the-art (SOA) algorithms. Furthermore, variants of the baseline MS-EEGNet were analyzed to evaluate the impact of different hyper-parameters on performance. Lastly, saliency maps were used to derive representations of the relevant spatio-temporal features that drove CNN decisions. MS-EEGNet was the lightest CNN compared with the tested SOA CNNs, despite its multiple timescales, and significantly outperformed the SOA algorithms. Post-hoc hyper-parameter analysis confirmed the benefits of the innovative aspects of MS-EEGNet. Furthermore, MS-EEGNet did benefit from transfer learning, especially using a low number of training examples, suggesting that the proposed approach could be used in BCIs to accurately decode the P300 event while reducing calibration times. Representations derived from the saliency maps matched the P300 spatio-temporal distribution, further validating the proposed decoding approach. This study, by specifically addressing the aspects of lightweight design, transfer learning, and interpretability, can contribute to advance the development of deep learning algorithms for P300-based BCIs

Collaborative Brain-Computer Interfaces in Rapid Image Presentation and Motion Pictures

The last few years have seen an increase in brain-computer interface (BCI) research for the able-bodied population. One of these new branches involves collaborative BCIs (cBCIs), in which information from several users is combined to improve the performance of a BCI system. This thesis is focused on cBCIs with the aim of increasing understanding of how they can be used to improve performance of single-user BCIs based on event-related potentials (ERPs). The objectives are: (1) to study and compare different methods of creating groups using exclusively electroencephalography (EEG) signals, (2) to develop a theoretical model to establish where the highest gains may be expected from creating groups, and (3) to analyse the information that can be extracted by merging signals from multiple users. For this, two scenarios involving real-world stimuli (images presented at high rates and movies) were studied. The first scenario consisted of a visual search task in which images were presented at high frequencies. Three modes of combining EEG recordings from different users were tested to improve the detection of different ERPs, namely the P300 (associated with the presence of events of interest) and the N2pc (associated with shifts of attention). We showed that the detection and localisation of targets can improve significantly when information from multiple viewers is combined. In the second scenario, feature movies were introduced to study variations in ERPs in response to cuts through cBCI techniques. A distinct, previously unreported, ERP appears in relation to such cuts, the amplitude of which is not modulated by visual effects such as the low-level properties of the frames surrounding the discontinuity. However, significant variations that depended on the movie were found. We hypothesise that these techniques can be used to build on the attentional theory of cinematic continuity by providing an extra source of information: the brain

Classification of Frequency and Phase Encoded Steady State Visual Evoked Potentials for Brain Computer Interface Speller Applications using Convolutional Neural Networks

Over the past decade there have been substantial improvements in vision based Brain-Computer Interface (BCI) spellers for quadriplegic patient populations. This thesis contains a review of the numerous bio-signals available to BCI researchers, as well as a brief chronology of foremost decoding methodologies used to date. Recent advances in classification accuracy and information transfer rate can be primarily attributed to time consuming patient specific parameter optimization procedures. The aim of the current study was to develop analysis software with potential ‘plug-in-and-play’ functionality. To this end, convolutional neural networks, presently established as state of the art analytical techniques for image processing, were utilized. The thesis herein defines deep convolutional neural network architecture for the offline classification of phase and frequency encoded SSVEP bio-signals. Networks were trained using an extensive 35 participant open source Electroencephalographic (EEG) benchmark dataset (Department of Bio-medical Engineering, Tsinghua University, Beijing). Average classification accuracies of 82.24% and information transfer rates of 22.22 bpm were achieved on a BCI naïve participant dataset for a 40 target alphanumeric display, in absence of any patient specific parameter optimization

Decoding Neural Activity to Assess Individual Latent State in Ecologically Valid Contexts

There exist very few ways to isolate cognitive processes, historically defined via highly controlled laboratory studies, in more ecologically valid contexts. Specifically, it remains unclear as to what extent patterns of neural activity observed under such constraints actually manifest outside the laboratory in a manner that can be used to make an accurate inference about the latent state, associated cognitive process, or proximal behavior of the individual. Improving our understanding of when and how specific patterns of neural activity manifest in ecologically valid scenarios would provide validation for laboratory-based approaches that study similar neural phenomena in isolation and meaningful insight into the latent states that occur during complex tasks. We argue that domain generalization methods from the brain-computer interface community have the potential to address this challenge. We previously used such an approach to decode phasic neural responses associated with visual target discrimination. Here, we extend that work to more tonic phenomena such as internal latent states. We use data from two highly controlled laboratory paradigms to train two separate domain-generalized models. We apply the trained models to an ecologically valid paradigm in which participants performed multiple, concurrent driving-related tasks. Using the pretrained models, we derive estimates of the underlying latent state and associated patterns of neural activity. Importantly, as the patterns of neural activity change along the axis defined by the original training data, we find changes in behavior and task performance consistent with the observations from the original, laboratory paradigms. We argue that these results lend ecological validity to those experimental designs and provide a methodology for understanding the relationship between observed neural activity and behavior during complex tasks

Interpretable Convolutional Neural Networks for Decoding and Analyzing Neural Time Series Data

Machine learning is widely adopted to decode multi-variate neural time series, including electroencephalographic (EEG) and single-cell recordings. Recent solutions based on deep learning (DL) outperformed traditional decoders by automatically extracting relevant discriminative features from raw or minimally pre-processed signals. Convolutional Neural Networks (CNNs) have been successfully applied to EEG and are the most common DL-based EEG decoders in the state-of-the-art (SOA). However, the current research is affected by some limitations. SOA CNNs for EEG decoding usually exploit deep and heavy structures with the risk of overfitting small datasets, and architectures are often defined empirically. Furthermore, CNNs are mainly validated by designing within-subject decoders. Crucially, the automatically learned features mainly remain unexplored; conversely, interpreting these features may be of great value to use decoders also as analysis tools, highlighting neural signatures underlying the different decoded brain or behavioral states in a data-driven way. Lastly, SOA DL-based algorithms used to decode single-cell recordings rely on more complex, slower to train and less interpretable networks than CNNs, and the use of CNNs with these signals has not been investigated. This PhD research addresses the previous limitations, with reference to P300 and motor decoding from EEG, and motor decoding from single-neuron activity. CNNs were designed light, compact, and interpretable. Moreover, multiple training strategies were adopted, including transfer learning, which could reduce training times promoting the application of CNNs in practice. Furthermore, CNN-based EEG analyses were proposed to study neural features in the spatial, temporal and frequency domains, and proved to better highlight and enhance relevant neural features related to P300 and motor states than canonical EEG analyses. Remarkably, these analyses could be used, in perspective, to design novel EEG biomarkers for neurological or neurodevelopmental disorders. Lastly, CNNs were developed to decode single-neuron activity, providing a better compromise between performance and model complexity

A comprehensive analysis of machine learning and deep learning models for identifying pilots’ mental states from imbalanced physiological data

This study focuses on identifying pilots' mental states linked to attention-related human performance-limiting states (AHPLS) using a publicly released, imbalanced physiological dataset. The research integrates electroencephalography (EEG) with non-brain signals, such as electrocardiogram (ECG), galvanic skin response (GSR), and respiration, to create a deep learning architecture that combines one-dimensional Convolutional Neural Network (1D-CNN) and Long Short-Term Memory (LSTM) models. Addressing the data imbalance challenge, the study employs resampling techniques, specifically downsampling with cosine similarity and oversampling using Synthetic Minority Over-sampling Technique (SMOTE), to produce balanced datasets for enhanced model performance. An extensive evaluation of various machine learning and deep learning models, including XGBoost, AdaBoost, Random Forest (RF), Feed-Forward Neural Network (FFNN), standalone 1D-CNN, and standalone LSTM, is conducted to determine their efficacy in detecting pilots' mental states. The results contribute to the development of efficient mental state detection systems, highlighting the XGBoost algorithm and the proposed 1D-CNN+LSTM model as the most promising solutions for improving safety and performance in aviation and other industries where monitoring mental states is essential

The Unbalanced Classification Problem: Detecting Breaches in Security

This research proposes several methods designed to improve solutions for security classification problems. The security classification problem involves unbalanced, high-dimensional, binary classification problems that are prevalent today. The imbalance within this data involves a significant majority of the negative class and a minority positive class. Any system that needs protection from malicious activity, intruders, theft, or other types of breaches in security must address this problem. These breaches in security are considered instances of the positive class. Given numerical data that represent observations or instances which require classification, state of the art machine learning algorithms can be applied. However, the unbalanced and high-dimensional structure of the data must be considered prior to applying these learning methods. High-dimensional data poses a “curse of dimensionality” which can be overcome through the analysis of subspaces. Exploration of intelligent subspace modeling and the fusion of subspace models is proposed. Detailed analysis of the one-class support vector machine, as well as its weaknesses and proposals to overcome these shortcomings are included. A fundamental method for evaluation of the binary classification model is the receiver operating characteristic (ROC) curve and the area under the curve (AUC). This work details the underlying statistics involved with ROC curves, contributing a comprehensive review of ROC curve construction and analysis techniques to include a novel graphic for illustrating the connection between ROC curves and classifier decision values. The major innovations of this work include synergistic classifier fusion through the analysis of ROC curves and rankings, insight into the statistical behavior of the Gaussian kernel, and novel methods for applying machine learning techniques to defend against computer intrusion detection. The primary empirical vehicle for this research is computer intrusion detection data, and both host-based intrusion detection systems (HIDS) and network-based intrusion detection systems (NIDS) are addressed. Empirical studies also include military tactical scenarios

Brain computer interfaces: an engineering view. Design, implementation and test of a SSVEP-based BCI.

This thesis presents the realization of a compact, yet flexible BCI platform, which, when compared to most commercially-available solution, can offer an optimal trade-off between the following requirements: (i) minimal, easy experimental setup; (ii) flexibility, allowing simultaneous studies on other bio-potentials; (iii) cost effectiveness (e.g. < 1000 €); (iv) robust design, suitable for operation outside lab environments. The thesis encompasses all the project phases, from hardware design and realization, up to software and signal processing. The work started from the development of the hardware acquisition unit. It resulted in a compact, battery-operated module, whose medium-to-large scale production costs are in the range of 300 €. The module features 16 input channels and can be used to acquire different bio-potentials, including EEG, EMG, ECG. Module performance is very good (RTI noise < 1.3 uVpp), and was favourably compared against a commercial device (g.tec USBamp). The device was integrated into an ad-hoc developed Matlab-based platform, which handles the hardware control, as well as the data streaming, logging and processing. Via a specifically developed plug-in, incoming data can also be streamed to a TOBI-interface compatible system. As a demonstrator, the BCI was developed for AAL (Ambient Assisted Living) system-control purposes, having in mind the following requirements: (i) online, self-paced BCI operation (i.e., the BCI monitors the EEG in real-time and must discern between intentional control periods, and non-intentional, rest ones, interpreting the user’s intent only in the first case); (ii) calibration-free approach (“ready-to-use”, “Plug&Play”); (iii) subject-independence (general approach). The choice of the BCI operating paradigm fell on Steady State visual Evoked Potential (SSVEP). Two offline SSVEP classification algorithms were proposed and compared against reference literature, highlighting good performance, especially in terms of lower computational complexity. A method for improving classification accuracy was presented, suitable for use in online, self-paced scenarios (since it can be used to discriminate between intentional control periods and non-intentional ones). Results show a very good performance, in particular in terms of false positives immunity (0.26 min^-1), significantly improving over the state of the art. The whole BCI setup was tested both in lab condition, as well as in relatively harsher ones (in terms of environmental noise and non-idealities), such as in the context of the Handimatica 2014 exhibition. In both cases, a demonstrator allowing control of home appliances through BCI was developed