33,178 research outputs found
Multi-timescale Solar Cycles and the Possible Implications
Based on analysis of the annual averaged relative sunspot number (ASN) during
1700 -- 2009, 3 kinds of solar cycles are confirmed: the well-known 11-yr cycle
(Schwabe cycle), 103-yr secular cycle (numbered as G1, G2, G3, and G4,
respectively since 1700); and 51.5-yr Cycle. From similarities, an
extrapolation of forthcoming solar cycles is made, and found that the solar
cycle 24 will be a relative long and weak Schwabe cycle, which may reach to its
apex around 2012-2014 in the vale between G3 and G4. Additionally, most Schwabe
cycles are asymmetric with rapidly rising-phases and slowly decay-phases. The
comparisons between ASN and the annual flare numbers with different GOES
classes (C-class, M-class, X-class, and super-flare, here super-flare is
defined as X10.0) and the annal averaged radio flux at frequency of 2.84
GHz indicate that solar flares have a tendency: the more powerful of the flare,
the later it takes place after the onset of the Schwabe cycle, and most
powerful flares take place in the decay phase of Schwabe cycle. Some
discussions on the origin of solar cycles are presented.Comment: 8 pages, 4 figure
The effect of ethnicity on the vascular responses to cold exposure of the extremities
This is an accepted manuscript of an article published by Springer in European Journal of Applied Physiology on 01/08/2014, available online: https://doi.org/10.1007/s00421-014-2962-2
The accepted version of the publication may differ from the final published version.© 2014, Springer-Verlag Berlin Heidelberg. Purpose: Cold injuries are more prevalent in individuals of African descent (AFD). Therefore, we investigated the effect of extremity cooling on skin blood flow (SkBF) and temperature (Tsk) between ethnic groups.Methods: Thirty males [10 Caucasian (CAU), 10 Asian (ASN), 10 AFD] undertook three tests in 30 °C air whilst digit Tsk and SkBF were measured: (i) vasomotor threshold (VT) test—arm immersed in 35 °C water progressively cooled to 10 °C and rewarmed to 35 °C to identify vasoconstriction and vasodilatation; (ii) cold-induced vasodilatation (CIVD) test—hand immersed in 8 °C water for 30 min followed by spontaneous warming; (iii) cold sensitivity (CS) test—foot immersed in 15 °C water for 2 min followed by spontaneous warming. Cold sensory thresholds of the forearm and finger were also assessed.Results: In the VT test, vasoconstriction and vasodilatation occurred at a warmer finger Tsk in AFD during cooling [21.2 (4.4) vs. 17.0 (3.1) °C, P = 0.034] and warming [22.0 (7.9) vs. 12.1 (4.1) °C, P = 0.002] compared with CAU. In the CIVD test, average SkBF during immersion was greater in CAU [42 (24) %] than ASN [25 (8) %, P = 0.036] and AFD [24 (13) %, P = 0.023]. Following immersion, SkBF was higher and rewarming faster in CAU [3.2 (0.4) °C min−1] compared with AFD [2.5 (0.7) °C min−1, P = 0.037], but neither group differed from ASN [3.0 (0.6) °C min−1]. Responses to the CS test and cold sensory thresholds were similar between groups.Conclusion: AFD experienced a more intense protracted finger vasoconstriction than CAU during hand immersion, whilst ASN experienced an intermediate response. This greater sensitivity to cold may explain why AFD are more susceptible to cold injuries.Published versio
The Triplet Genetic Code had a Doublet Predecessor
Information theoretic analysis of genetic languages indicates that the
naturally occurring 20 amino acids and the triplet genetic code arose by
duplication of 10 amino acids of class-II and a doublet genetic code having
codons NNY and anticodons . Evidence for this scenario
is presented based on the properties of aminoacyl-tRNA synthetases, amino acids
and nucleotide bases.Comment: 10 pages (v2) Expanded to include additional features, including
likely relation to the operational code of the tRNA-acceptor stem. Version to
be published in Journal of Theoretical Biolog
Computing by Temporal Order: Asynchronous Cellular Automata
Our concern is the behaviour of the elementary cellular automata with state
set 0,1 over the cell set Z/nZ (one-dimensional finite wrap-around case), under
all possible update rules (asynchronicity).
Over the torus Z/nZ (n<= 11),we will see that the ECA with Wolfram rule 57
maps any v in F_2^n to any w in F_2^n, varying the update rule.
We furthermore show that all even (element of the alternating group)
bijective functions on the set F_2^n = 0,...,2^n-1, can be computed by ECA57,
by iterating it a sufficient number of times with varying update rules, at
least for n <= 10. We characterize the non-bijective functions computable by
asynchronous rules.Comment: In Proceedings AUTOMATA&JAC 2012, arXiv:1208.249
Towards Understanding the Origin of Genetic Languages
Molecular biology is a nanotechnology that works--it has worked for billions
of years and in an amazing variety of circumstances. At its core is a system
for acquiring, processing and communicating information that is universal, from
viruses and bacteria to human beings. Advances in genetics and experience in
designing computers have taken us to a stage where we can understand the
optimisation principles at the root of this system, from the availability of
basic building blocks to the execution of tasks. The languages of DNA and
proteins are argued to be the optimal solutions to the information processing
tasks they carry out. The analysis also suggests simpler predecessors to these
languages, and provides fascinating clues about their origin. Obviously, a
comprehensive unraveling of the puzzle of life would have a lot to say about
what we may design or convert ourselves into.Comment: (v1) 33 pages, contributed chapter to "Quantum Aspects of Life",
edited by D. Abbott, P. Davies and A. Pati, (v2) published version with some
editin
Pseudomonas Cytochrome c551 at 2.0 angstrom Resolution: Enlargement of the Cytochrome c Family
The structure of respiratory cytochrome c551 of Pseudomonas aeruginosa, with 82 amino acids, has been solved by x-ray analysis and refined to a crystallographic R factor of 16.2%. It has the same basic folding pattern and hydrophobic heme environment as cytochromes c, c2, and c550, except for a large deletion at the bottom of the heme crevice. This same "cytochrome fold" appears to be present in photosynthetic cytochromes c of green and purple sulfur bacteria, and algal cytochromes f, suggesting a common evolutionary origin for electron transport chains in photosynthesis and respiration
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