99,674 research outputs found
Architecture and Design of Medical Processor Units for Medical Networks
This paper introduces analogical and deductive methodologies for the design
medical processor units (MPUs). From the study of evolution of numerous earlier
processors, we derive the basis for the architecture of MPUs. These specialized
processors perform unique medical functions encoded as medical operational
codes (mopcs). From a pragmatic perspective, MPUs function very close to CPUs.
Both processors have unique operation codes that command the hardware to
perform a distinct chain of subprocesses upon operands and generate a specific
result unique to the opcode and the operand(s). In medical environments, MPU
decodes the mopcs and executes a series of medical sub-processes and sends out
secondary commands to the medical machine. Whereas operands in a typical
computer system are numerical and logical entities, the operands in medical
machine are objects such as such as patients, blood samples, tissues, operating
rooms, medical staff, medical bills, patient payments, etc. We follow the
functional overlap between the two processes and evolve the design of medical
computer systems and networks.Comment: 17 page
The skyrmion-bubble transition in a ferromagnetic thin film
Magnetic skyrmions and bubbles, observed in ferromagnetic thin films with
perpendicular magnetic anisotropy, are topological solitons which differ by
their characteristic size and the balance in the energies at the origin of
their stabilisation. However, these two spin textures have the same topology
and a continuous transformation between them is allowed. In the present work,
we derive an analytical model to explore the skyrmion-bubble transition. We
evidence a region in the parameter space where both topological soliton
solutions coexist and close to which transformations between skyrmion and
bubbles are observed as a function of the magnetic field. Above a critical
point, at which the energy barrier separating both solutions vanishes, only one
topological soliton solution remains, which size can be continuously tuned from
micrometer to nanometer with applied magnetic field
The words of the body: psychophysiological patterns in dissociative narratives
Trauma has severe consequences on both psychological and somatic levels, even affecting the genetic expression and the cell\u2019s DNA repair ability. A key mechanism in the understanding of clinical disorders deriving from trauma is identified in dissociation, as a primitive defense against the fragmentation of the self originated by overwhelming experiences. The dysregulation of the interpersonal patterns due to the traumatic experience and its detrimental effects on the body are supported by influent neuroscientific models such as Damasio\u2019s somatic markers and Porges\u2019 polyvagal theory. On the basis of these premises, and supported by our previous empirical observations on 40 simulated clinical sessions, we will discuss the longitudinal process of a brief psychodynamic psychotherapy (16 sessions, weekly frequency) with a patient who suffered a relational trauma. The research design consists of the collection of self-report and projective tests, pre-post therapy and after each clinical session, in order to assess personality, empathy, clinical alliance and clinical progress, along with the verbatim analysis of the transcripts trough the Psychotherapy Process Q-Set and the Collaborative Interactions Scale. Furthermore, we collected simultaneous psychophysiological measures of the therapeutic dyad: skin conductance and hearth rate. Lastly, we employed a computerized analysis of non-verbal behaviors to assess synchrony in posture and gestures. These automated measures are able to highlight moments of affective concordance and discordance, allowing for a deep understanding of the mutual regulations between the patient and the therapist. Preliminary results showed that psychophysiological changes in dyadic synchrony, observed in body movements, skin conductance and hearth rate, occurred within sessions during the discussion of traumatic experiences, with levels of attunement that changed in both therapist and the patient depending on the quality of the emotional representation of the experience. These results go in the direction of understanding the relational process in trauma therapy, using an integrative language in which both clinical and neurophysiological knowledge may take advantage of each other
A review of High Performance Computing foundations for scientists
The increase of existing computational capabilities has made simulation
emerge as a third discipline of Science, lying midway between experimental and
purely theoretical branches [1, 2]. Simulation enables the evaluation of
quantities which otherwise would not be accessible, helps to improve
experiments and provides new insights on systems which are analysed [3-6].
Knowing the fundamentals of computation can be very useful for scientists, for
it can help them to improve the performance of their theoretical models and
simulations. This review includes some technical essentials that can be useful
to this end, and it is devised as a complement for researchers whose education
is focused on scientific issues and not on technological respects. In this
document we attempt to discuss the fundamentals of High Performance Computing
(HPC) [7] in a way which is easy to understand without much previous
background. We sketch the way standard computers and supercomputers work, as
well as discuss distributed computing and discuss essential aspects to take
into account when running scientific calculations in computers.Comment: 33 page
JANUS: an FPGA-based System for High Performance Scientific Computing
This paper describes JANUS, a modular massively parallel and reconfigurable
FPGA-based computing system. Each JANUS module has a computational core and a
host. The computational core is a 4x4 array of FPGA-based processing elements
with nearest-neighbor data links. Processors are also directly connected to an
I/O node attached to the JANUS host, a conventional PC. JANUS is tailored for,
but not limited to, the requirements of a class of hard scientific applications
characterized by regular code structure, unconventional data manipulation
instructions and not too large data-base size. We discuss the architecture of
this configurable machine, and focus on its use on Monte Carlo simulations of
statistical mechanics. On this class of application JANUS achieves impressive
performances: in some cases one JANUS processing element outperfoms high-end
PCs by a factor ~ 1000. We also discuss the role of JANUS on other classes of
scientific applications.Comment: 11 pages, 6 figures. Improved version, largely rewritten, submitted
to Computing in Science & Engineerin
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