The Restoration of UNIX: Emulating UNIX version 1.0 on a 16-bit DEC PDP 11/20

Next year, the one of the world’s first Operating Systems (OS) UNIX will celebrate its 50th birthday. This relic of the past is objectively one of the most important creations that has ever influenced the field of Computer Science. However, mysteries of this artifact were discovered in 1995. Two engineers, Paul Vixie and Keith Bostic, dug deep enough to find several DEC tapes “under the floor of the computer room [at Bell Labs]” (UNIX Past) which held several original binary files for UNIX. With much help from several individuals, these two engineers were able to reverse engineer the binary tapes they found and 15 years later, put up a repository for this ancient system on GitHub. There it has stayed, waiting for someone to use it like it was meant to be used, on a DEC PDP 11/20, the computer UNIX v1 was initially written for. Currently, the PDP 11/20 can send and receive data via a homemade serial emulator we have written in Java, and the PDP 11/20 has been loaded with a binary file for the BASIC programming language. Once the entry point for BASIC can be determined, we will start to write code to emulate paper tape readers to assist in loading UNIX v1 into the PDP 11/20\u27s memory. In the end, we hope to have a fully functional system running the one of the world’s first Operating Systems

Focal Spot, Spring 1999

https://digitalcommons.wustl.edu/focal_spot_archives/1081/thumbnail.jp

Computer-assisted detection of lung cancer nudules in medical chest X-rays

Diagnostic medicine was revolutionized in 1895 with Rontgen's discovery of x-rays. X-ray photography has played a very prominent role in diagnostics of all kinds since then and continues to do so. It is true that more sophisticated and successful medical imaging systems are available. These include Magnetic Resonance Imaging (MRI), Computerized Tomography (CT) and Positron Emission Tomography (PET). However, the hardware instalment and operation costs of these systems remain considerably higher than x-ray systems. Conventional x-ray photography also has the advantage of producing an image in significantly less time than MRI, CT and PET. X-ray photography is still used extensively, especially in third world countries. The routine diagnostic tool for chest complaints is the x-ray. Lung cancer may be diagnosed by the identification of a lung cancer nodule in a chest x-ray. The cure of lung cancer depends upon detection and diagnosis at an early stage. Presently the five-year survival rate of lung cancer patients is approximately 10%. If lung cancer can be detected when the tumour is still small and localized, the five-year survival rate increases to about 40%. However, currently only 20% of lung cancer cases are diagnosed at this early stage. Giger et al wrote that "detection and diagnosis of cancerous lung nodules in chest radiographs are among the most important and difficult tasks performed by radiologists"

A Guide to Distributed Digital Preservation

This volume is devoted to the broad topic of distributed digital preservation, a still-emerging field of practice for the cultural memory arena. Replication and distribution hold out the promise of indefinite preservation of materials without degradation, but establishing effective organizational and technical processes to enable this form of digital preservation is daunting. Institutions need practical examples of how this task can be accomplished in manageable, low-cost ways."--P. [4] of cove

Preservation and Promotion of Opera Cultural Heritage: The Experience of La Scala Theatre

This paper focuses on music and music-related cultural heritage typically preserved by opera houses, starting from the experience achieved during the long-lasting collaboration between La Scala theater and the Laboratory of Music Informatics of the University of Milan. First, we will mention the most significant results achieved by the project in the fields of preservation, information retrieval and dissemination of cultural heritage through computer-based approaches. Moreover, we will discuss the possibilities offered by new technologies applied to the conservative context of an opera house, including: the multi-layer representation of music information to foster the accessibility of musical content also by non-experts; the adoption of 5G networks to deliver spherical videos of live events, thus opening new scenarios for cultural heritage enjoyment and dissemination; deep learning approaches both to improve internal processes (e.g., back-office applications for music information retrieval) and to offer advanced services to users (e.g., highly-customized experiences)

Second Annual Conference on Astronomical Data Analysis Software and Systems. Abstracts

Abstracts from the conference are presented. The topics covered include the following: next generation software systems and languages; databases, catalogs, and archives; user interfaces/visualization; real-time data acquisition/scheduling; and IRAF/STSDAS/PROS status reports

A Neuroimaging Web Interface for Data Acquisition, Processing and Visualization of Multimodal Brain Images

Structural and functional brain images are generated as essential modalities for medical experts to learn about the different functions of the brain. These images are typically visually inspected by experts. Many software packages are available to process medical images, but they are complex and difficult to use. The software packages are also hardware intensive. As a consequence, this dissertation proposes a novel Neuroimaging Web Services Interface (NWSI) as a series of processing pipelines for a common platform to store, process, visualize and share data. The NWSI system is made up of password-protected interconnected servers accessible through a web interface. The web-interface driving the NWSI is based on Drupal, a popular open source content management system. Drupal provides a user-based platform, in which the core code for the security and design tools are updated and patched frequently. New features can be added via modules, while maintaining the core software secure and intact. The webserver architecture allows for the visualization of results and the downloading of tabulated data. Several forms are ix available to capture clinical data. The processing pipeline starts with a FreeSurfer (FS) reconstruction of T1-weighted MRI images. Subsequently, PET, DTI, and fMRI images can be uploaded. The Webserver captures uploaded images and performs essential functionalities, while processing occurs in supporting servers. The computational platform is responsive and scalable. The current pipeline for PET processing calculates all regional Standardized Uptake Value ratios (SUVRs). The FS and SUVR calculations have been validated using Alzheimer\u27s Disease Neuroimaging Initiative (ADNI) results posted at Laboratory of Neuro Imaging (LONI). The NWSI system provides access to a calibration process through the centiloid scale, consolidating Florbetapir and Florbetaben tracers in amyloid PET images. The interface also offers onsite access to machine learning algorithms, and introduces new heat maps that augment expert visual rating of PET images. NWSI has been piloted using data and expertise from Mount Sinai Medical Center, the 1Florida Alzheimer’s Disease Research Center (ADRC), Baptist Health South Florida, Nicklaus Children\u27s Hospital, and the University of Miami. All results were obtained using our processing servers in order to maintain data validity, consistency, and minimal processing bias