Visualization and Correction of Automated Segmentation, Tracking and Lineaging from 5-D Stem Cell Image Sequences

Results: We present an application that enables the quantitative analysis of multichannel 5-D (x, y, z, t, channel) and large montage confocal fluorescence microscopy images. The image sequences show stem cells together with blood vessels, enabling quantification of the dynamic behaviors of stem cells in relation to their vascular niche, with applications in developmental and cancer biology. Our application automatically segments, tracks, and lineages the image sequence data and then allows the user to view and edit the results of automated algorithms in a stereoscopic 3-D window while simultaneously viewing the stem cell lineage tree in a 2-D window. Using the GPU to store and render the image sequence data enables a hybrid computational approach. An inference-based approach utilizing user-provided edits to automatically correct related mistakes executes interactively on the system CPU while the GPU handles 3-D visualization tasks. Conclusions: By exploiting commodity computer gaming hardware, we have developed an application that can be run in the laboratory to facilitate rapid iteration through biological experiments. There is a pressing need for visualization and analysis tools for 5-D live cell image data. We combine accurate unsupervised processes with an intuitive visualization of the results. Our validation interface allows for each data set to be corrected to 100% accuracy, ensuring that downstream data analysis is accurate and verifiable. Our tool is the first to combine all of these aspects, leveraging the synergies obtained by utilizing validation information from stereo visualization to improve the low level image processing tasks.Comment: BioVis 2014 conferenc

L\'{e}vy flights in inhomogeneous environments

We study the long time asymptotics of probability density functions (pdfs) of L\'{e}vy flights in different confining potentials. For that we use two models: Langevin - driven and (L\'{e}vy - Schr\"odinger) semigroup - driven dynamics. It turns out that the semigroup modeling provides much stronger confining properties than the standard Langevin one. Since contractive semigroups set a link between L\'{e}vy flights and fractional (pseudo-differential) Hamiltonian systems, we can use the latter to control the long - time asymptotics of the pertinent pdfs. To do so, we need to impose suitable restrictions upon the Hamiltonian and its potential. That provides verifiable criteria for an invariant pdf to be actually an asymptotic pdf of the semigroup-driven jump-type process. For computational and visualization purposes our observations are exemplified for the Cauchy driver and its response to external polynomial potentials (referring to L\'{e}vy oscillators), with respect to both dynamical mechanisms.Comment: Major revisio

Applying Block Chain Technologies to Digital Voting Algorithms

Voting is a fundamental aspect to democracy. Many countries have advanced voting systems in place, but many of these systems have issues behind them such as not being anonymous or verifiable. Additionally, most voting systems currently have a central authority in charge of counting votes, which can be prone to corruption. We propose a voting system which mitigates many of these issues. Our voting system attempts to provide decentralization, pseudoanonymity, and verifiability. For our system, we have identified the requirements, implemented the backbone of the system, recognized some of its shortcomings, and proposed areas of future work on this voting system

Link Before You Share: Managing Privacy Policies through Blockchain

With the advent of numerous online content providers, utilities and applications, each with their own specific version of privacy policies and its associated overhead, it is becoming increasingly difficult for concerned users to manage and track the confidential information that they share with the providers. Users consent to providers to gather and share their Personally Identifiable Information (PII). We have developed a novel framework to automatically track details about how a users' PII data is stored, used and shared by the provider. We have integrated our Data Privacy ontology with the properties of blockchain, to develop an automated access control and audit mechanism that enforces users' data privacy policies when sharing their data across third parties. We have also validated this framework by implementing a working system LinkShare. In this paper, we describe our framework on detail along with the LinkShare system. Our approach can be adopted by Big Data users to automatically apply their privacy policy on data operations and track the flow of that data across various stakeholders.Comment: 10 pages, 6 figures, Published in: 4th International Workshop on Privacy and Security of Big Data (PSBD 2017) in conjunction with 2017 IEEE International Conference on Big Data (IEEE BigData 2017) December 14, 2017, Boston, MA, US

HR Analytics: Talent Acquisition

[Excerpt] HR Analytics is becoming increasingly important as new technologies, software and new methods of data collection are revolutionizing the HR function. One area in which analytics tools are particularly flourishing is the talent acquisition space. With an increasingly competitive talent market, talent acquisition presents itself as an area in which analytics tools can greatly supplement decision making for these 3 reasons: here are many measurable, verifiable metrics to measure in terms of sources of talent, candidate qualifications, and the efficacy of the recruitment process here is an abundance of sources from which to collect data (Online sources, interviews, etc.) With the increased importance of sourcing the correct talent, the opportunity to use analytics tools to make better decisions is quite compelling Given these reasons, talent acquisition presents itself as an opportunity for organizations to build their analytics capabilities while driving measurable business outcomes and improvements to their organization. As evidenced in the above graphic, many organizations are already undertaking these changes or considering changes in the near future

A fine-tuned global distribution dataset of marine forests

Species distribution records are a prerequisite to follow climate-induced range shifts across space and time. However, synthesizing information from various sources such as peer-reviewed literature, herbaria, digital repositories and citizen science initiatives is not only costly and time consuming, but also challenging, as data may contain thematic and taxonomic errors and generally lack standardized formats. We address this gap for important marine ecosystem-structuring species of large brown algae and seagrasses. We gathered distribution records from various sources and provide a fine-tuned dataset with ~2.8 million dereplicated records, taxonomically standardized for 682 species, and considering important physiological and biogeographical traits. Specifically, a flagging system was implemented to signal potentially incorrect records reported on land, in regions with limiting light conditions for photosynthesis, and outside the known distribution of species, as inferred from the most recent published literature. We document the procedure and provide a dataset in tabular format based on Darwin Core Standard (DwC), alongside with a set of functions in R language for data management and visualization.FCT: (SFRH/BPD/111003/2015) / (SFRH/BSAB/150485/2019) / (SFRH/BD/144878/2019)(PTDC/MAREST/6053/2014) / MARFOR (BIODIVERSA/004/2015) / UIDB/04326/2020info:eu-repo/semantics/publishedVersio

Investigating Rumor Propagation with TwitterTrails

Social media have become part of modern news reporting, used by journalists to spread information and find sources, or as a news source by individuals. The quest for prominence and recognition on social media sites like Twitter can sometimes eclipse accuracy and lead to the spread of false information. As a way to study and react to this trend, we introduce {\sc TwitterTrails}, an interactive, web-based tool ({\tt twittertrails.com}) that allows users to investigate the origin and propagation characteristics of a rumor and its refutation, if any, on Twitter. Visualizations of burst activity, propagation timeline, retweet and co-retweeted networks help its users trace the spread of a story. Within minutes {\sc TwitterTrails} will collect relevant tweets and automatically answer several important questions regarding a rumor: its originator, burst characteristics, propagators and main actors according to the audience. In addition, it will compute and report the rumor's level of visibility and, as an example of the power of crowdsourcing, the audience's skepticism towards it which correlates with the rumor's credibility. We envision {\sc TwitterTrails} as valuable tool for individual use, but we especially for amateur and professional journalists investigating recent and breaking stories. Further, its expanding collection of investigated rumors can be used to answer questions regarding the amount and success of misinformation on Twitter.Comment: 10 pages, 8 figures, under revie

On the Treatment of Field Quantities and Elemental Continuity in FEM Solutions

As the finite element method (FEM) and the finite volume method (FVM), both traditional and high-order variants, continue their proliferation into various applied engineering disciplines, it is important that the visualization techniques and corresponding data analysis tools that act on the results produced by these methods faithfully represent the underlying data. To state this in another way: the interpretation of data generated by simulation needs to be consistent with the numerical schemes that underpin the specific solver technology. As the verifiable visualization literature has demonstrated: visual artifacts produced by the introduction of either explicit or implicit data transformations, such as data resampling, can sometimes distort or even obfuscate key scientific features in the data. In this paper, we focus on the handling of elemental continuity, which is often only C0 continuous or piecewise discontinuous, when visualizing primary or derived fields from FEM or FVM simulations. We demonstrate that traditional data handling and visualization of these fields introduce visual errors. In addition, we show how the use of the recently proposed line-SIAC filter provides a way of handling elemental continuity issues in an accuracy-conserving manner with the added benefit of casting the data in a smooth context even if the representation is element discontinuous