The role of light microscopy in aerospace analytical laboratories

Light microscopy has greatly reduced analytical flow time and added new dimensions to laboratory capability. Aerospace analytical laboratories are often confronted with problems involving contamination, wear, or material inhomogeneity. The detection of potential problems and the solution of those that develop necessitate the most sensitive and selective applications of sophisticated analytical techniques and instrumentation. This inevitably involves light microscopy. The microscope can characterize and often identify the cause of a problem in 5-15 minutes with confirmatory tests generally less than one hour. Light microscopy has and will make a very significant contribution to the analytical capabilities of aerospace laboratories

In Vivo Characterization of a Wireless Telemetry Module for a Capsule Endoscopy System Utilizing a Conformal Antenna

This paper describes the design, fabrication, packaging, and performance characterization of a conformal helix antenna created on the outside of a 10 mm ×30 mm capsule endoscope designed to operate at a carrier frequency of 433 MHz within human tissue. Wireless data transfer was established between the integrated capsule system and an external receiver. The telemetry system was tested within a tissue phantom and in vivo porcine models. Two different types of transmission modes were tested. The first mode, replicating normal operating conditions, used data packets at a steady power level of 0 dBm, while the capsule was being withdrawn at a steady rate from the small intestine. The second mode, replicating the worst-case clinical scenario of capsule retention within the small bowel, sent data with stepwise increasing power levels of –10, 0, 6, and 10 dBm, with the capsule fixed in position. The temperature of the tissue surrounding the external antenna was monitored at all times using thermistors embedded within the capsule shell to observe potential safety issues. The recorded data showed, for both modes of operation, a low error transmission of 10−3 packet error rate and 10−5 bit error rate and no temperature increase of the tissue according to IEEE standards

Conceptualization and Fabrication of a Bioinspired Mobile Robot Actuated by Shape Memory Alloy Springs

This work is an experimental study and fabrication of design concepts to validate the feasibility of smart materials and their applications in bio-inspired robotics. Shape-Memory Alloy (SMA) springs are selected as the smart material actuators of interest to achieve locomotion in the proposed mobile robot. Based on a previous design of the robot, this work focuses on both implementing a new locomotion concept and reducing size and weight of the previous design, both using SMA based actuators. Objectives are met in consideration of the conceptual mechanics of circular robot locomotion. The first prototype is a variation of the original design. It consists of a soft, rubber outer shell with three intrinsically attached diametric SMA springs that deform the outer shell during contraction and relaxation. The springs were provided with electrical current in patterns to produce deformation needed to generate momentum and allow the robot to tumble and roll. This design was further improved to provide more stability while rolling. The second design concept is a modification of our previous design leading to reduction in size and weight while maintaining essentially the same mechanism of locomotion. In this case, the SMA springs were externally configured between the end of equi-spaced spokes and the circular core. Upon actuation, the spokes function as diametrically translating legs to generate locomotion. These design concepts are fabricated and experimented on, to determine their feasibility, i.e. whether rolling/tumbling motion is achieved. The scope of the project was limited to demonstration of basic locomotion, which was successful. Future work on this project will address the design of automatic control to generate motion using closed-loop sensor-based actuation

Scaled Synthetic Aperture Radar System Development

Synthetic Aperture Radar (SAR) systems generate two dimensional images of a target area using RF energy as opposed to light waves used by cameras. When cloud cover or other optical obstructions prevent camera imaging over a target area, SAR can be substituted to generate high resolution images. Linear frequency modulated signals are transmitted and received while a moving imaging platform traverses a target area to develop high resolution images through modern digital signal processing (DSP) techniques. The motivation for this joint thesis project is to design and construct a scaled SAR system to support Cal Poly radar projects. Objectives include low-cost, high resolution SAR architecture development for capturing images in desired target areas. To that end, a scaled SAR system was successfully designed, built, and tested. The current SAR system, however, does not perform azimuthal compression and range cell migration correction (image blur reduction). These functionalities can be pursued by future students joining the ongoing radar project. The SAR system includes RF modulating, demodulating, and amplifying circuitry, broadband antenna design, movement platform, LabView system control, and MATLAB signal processing. Each system block is individually described and analyzed followed by final measured data. To confirm system operation, images developed from data collected in a single target environment are presented and compared to the actual configuration

Conformal antenna-based wireless telemetry system for capsule endoscopy

Capsule endoscopy for imaging the gastrointestinal tract is an innovative tool for carrying out medical diagnosis and therapy. Additional modalities beyond optical imaging would enhance current capabilities at the expense of denser integration, due to the limited space available within the capsule. We therefore need new designs and technologies to increase the smartness of the capsules for a given volume. This thesis presents the design, manufacture and performance characterisation of a helical antenna placed conformally outside an endoscopic capsule, and the characterisation in-silico, in-vitro and in-vivo of the telemetry system in alive and euthanised pigs. This method does not use the internal volume of the capsule, but does use an extra coating to protect the antenna from the surrounding tissue and maintain biocompatibility for safe use inside the human body. The helical antenna, radiating at 433 MHz with a bandwidth of 20 MHz within a muscle-type tissue, presents a low gain and efficiency, which is typical for implantable and ingestible medical devices. Telemetry capsule prototypes were simulated, manufactured and assembled with the necessary internal electronics, including a commercially available transceiver unit. Thermistors were embedded into each capsule shell, to record any temperature increase in the tissue surrounding the antenna during the experiments. A temperature increase of less than 1°C was detected for the tissue surrounding the antenna. The process of coating the biocompatible insulation layer over the full length of the capsule is described in detail. Data transmission programmes were established to send programmed data packets to an external receiver. The prototypes radiated at different power levels ranging from -10 to 10 dBm, and all capsules demonstrated a satisfactory performance at a data rate of 16 kbps during phantom and in-vivo experiments. Data transmission was achieved with low bit-error rates below 10-5. A low signal strength of only -54 dBm still provided effective data transfer, irrespective of the orientation and location of the capsule, and this successfully demonstrated the feasibility of the system

Design and implementation of a low-cost FMCW imaging radar

Imaging radar systems have been predominantly developed using a coherent pulse radar approach, which is typically associated with expensive and complex hardware that usually requires a large amount of space. Hence, the use of such sensors is reserved to large organizations that can afford to purchase or develop them. This is unfortunate as there are numerous uses for imaging radar sensors in both military and civilian sectors. One of such uses lies in the agricultural sector and entails using imaging radar data to monitor crop development. As a result, a project was initiated at the University of Cape Town (UCT), in collaboration with droneSAR company, which aimed to develop a low-cost, compact, imaging radar that could be mounted on a small Unmanned Aerial Vehicle (UAV). The purpose of this research project is aimed at developing the first system prototype. The RadioCamera-S is the S-band FMCW radar, that was developed to test the architecture that could be utilised to enable the filtering of the feed-through and nadir components, which are typically the strongest returns in the spectrum. The prototype has two modes of operation that are aimed at shifting the unwanted signals outside of the pass band of the receiver. This is achieved by generating two identical L-FMCW waveforms that are offset by a chosen time period. This enables a shift of the spectrum by the frequency, which corresponds to the time offset. The capabilities of the proposed hardware were examined and the specifications for the ground based version were developed. The parameters that influence the wave-form design were discussed and the optimal values were chosen for the ground based radar system. Verification of the transmitter and receiver operation was carried out, which was followed by system tests that demonstrated that the feed-through signal could be attenuated by employing the first proposed mode of operation. RTI plots were generated and showed that the radar was capable of detecting the movement of a reflector in the observable scene

RSL ROVER: Robotic Systems Laboratory Rugged Offroad Vehicle for Experimental Research

The goal of this project was to build an autonomous vehicle testbed for the Robotics Systems Laboratory. This testbed will be used by undergraduate, graduate, and faculty researchers to test different control methods, sensor combinations, vehicle control laws, and eventually autonomous navigation. This paper documents our accomplishments to achieve this goal; we built a hierarchical control system, robust actuator mounts, and an effective safety system. The result is a capable 6-wheeled offroad vehicle that can be electronically controlled by remote or directly by wire. A feed-forward control law was incorporated for speed control, yielding predictable performance given a desired speed. Actuators were tuned for fast, reliable response and wiring was kept organized. The team believes the vehicle will be a useful asset to the Robotic Systems Lab for future research. To improve upon our testbed, global positioning and a compass should be integrated along with other sensors that came with the vehicle such as a Lidar unit. With these additional components, the vehicle should be able to run autonomously

Modelling Hospital Materials Management Processes

Materials management is an important issue for healthcare systems because it influences clinical and financial outcomes. Before selecting, adapting and implementing leading or optimized practices, a good understanding of processes and activities has to be developed. In real applications, the information flows and business strategies involved are different from hospital to hospital, depending on context, culture and available resources; it is therefore difficult to find a comprehensive and exhaustive description of processes, even more so a clear formalization of them. The objective of this paper is twofold. First, it proposes an integrated and detailed analysis and description model for hospital materials management data and tasks, which is able to tackle information from patient requirements to usage, from replenishment requests to supplying and handling activities. The model takes account of medical risk reduction, traceability and streamlined processes perspectives. Second, the paper translates this information into a business process model and mathematical formalization. The study provides a useful guide to the various relevant technology-related, management and business issues, laying the foundations of an efficient reengineering of the supply chain to reduce healthcare costs and improve the quality of care

Mid-Infrared Integrated Devices for Optical Chemical Sensing

The mid-infrared (MIR) spectral range is of special interest for establishing optical chemical sensor technologies by allowing specific molecular identification and quantification, whether the sample is in a liquid, gas or solid form, in addition to providing highly sensitive, rapid, reagent-free and non-destructive detection. This thesis explores four different liquid- and gas- sensing applications and methods using MIR spectroscopy by integrating it with other technologies, such as microfluidics and fibre-optics. Firstly, fibre-optic integrated microfluidic devices were developed and tested for con- tinuous fluid monitoring. These showed good sensing capabilities for online, continuous and real-time liquid sensing in hard-to-reach locations. Next, this thesis presents the establishment and clinical testing of a novel method for continuous monitoring of the brain chemistry of traumatically brain-injured patients by MIR transmission spectroscopy. Here, the outlet of a cerebral microdialysis catheter is cou- pled to a micro flow-cell and the flowing microdialysate is continuously analysed. Clinical studies were carried out and showed the capability of this system for performing continuous patient monitoring over several hours. With further optimisation, the implementation of this system could lead to improved patient outcome. This thesis also presents a novel method and system based on MIR fibre-optic evanescent- wave spectroscopy, which enables enhanced detection of volatile organic compounds (VOCs). Here, a nanoporous silicon cladding was used to reversibly concentrate molecules close to the fibre surface, thus enhancing VOC detection. A significant increase in sen- sitivity was seen compared to that of an uncoated fibre and successful detection of three different VOCs, both independently and in binary mixtures, was achieved. Finally, this thesis introduces a simple and relatively low-cost fibre-optic sensor for in-line, real-time bioprocess monitoring. The sensor was successfully able to monitor varying concentrations of product (sophorolipids) in fermentation broth and was able to distinguish between the two types of generated product (acidic and lactonic sophorolipids). The work presented in this thesis showed that MIR-integrated sensors have great potential to provide novel and/or enhanced sensing solutions in a wide range of applications, including medical, industrial and environmental

33rd Aerospace Mechanisms Symposium

The proceedings of the 33rd Aerospace Mechanisms Symposium are reported. JPL hosted the conference, which was held at the Pasadena Conference and Exhibition Center, Pasadena, California, on May 19-21, 1999. Lockheed Martin Missiles and Space cosponsored the symposium. Technology areas covered include bearings and tribology; pointing, solar array and deployment mechanisms; orbiter/space station; and other mechanisms for spacecraft