20,341 research outputs found

    Liver homotransplantation

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    Liver homotransplantation

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    Transplantation of the liver

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    Transplantation of the liver in human subjects

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    Transplantation and other aspects of surgery of the liver

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    How to Identify Scientifc Revolutions?

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    Conceptualizing scientific revolutions by means of explicating their causes, their underlying structure and implications has been an important part of Kuhn's philosophy of science and belongs to its legacy. In this paper we show that such “explanatory concepts” of revolutions should be distinguished from a concept based on the identification criteria of scientific revolutions. The aim of this paper is to offer such a concept, and to show that it can be fruitfully used for a further elaboration of the explanatory conceptions of revolutions. On the one hand, our concept can be used to test the preciseness and accuracy of these conceptions, by examining to what extent their criteria fit revolutions as they are defined by our concept. On the other hand, our concept can serve as the basis on which these conceptions can be further specified. We will present four different explanatory concepts of revolutions – Kuhn's, Thagard's, Chen's and Barker's, and Laudan's – and point to the ways in which each of them can be further specified in view of our concept

    Fifteen years of clinical liver transplantation

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    Liver transplantation in humans was first attempted more than 15 yr ago. The 1-yr survival has slowly improved until it has now reached about 50%. In our experience, 46 patients have lived for at least 1 yr, with the longest survival being 9 yr. The high acute mortality in early trials was due in many cases to technical and management errors and to the use of damaged organs. With elimination of such factors, survival increased. Further improvements will depend upon better immunosuppression. Orthotopic liver transplantation (liver replacement) is the preferred operation in most cases, but placement of an extra liver (auxiliary transplantation) may have a role under special circumstances. © 1979

    Liver transplantation: From the laboratory to the clinic and beyond

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