163,917 research outputs found
A taxonomy of asymmetric requirements aspects
The early aspects community has received increasing attention among researchers and practitioners, and has grown a set of meaningful terminology and concepts in recent years, including the notion of requirements aspects. Aspects at the requirements level present stakeholder concerns that crosscut the problem domain, with the potential for a broad impact on questions of scoping, prioritization, and architectural design. Although many existing requirements engineering approaches advocate and advertise an integral support of early aspects analysis, one challenge is that the notion of a requirements aspect is not yet well established to efficaciously serve the community. Instead of defining the term once and for all in a normally arduous and unproductive conceptual unification stage, we present a preliminary taxonomy based on the literature survey to show the different features of an asymmetric requirements aspect. Existing approaches that handle requirements aspects are compared and classified according to the proposed taxonomy. In addition,we study crosscutting security requirements to exemplify the taxonomy's use, substantiate its value, and explore its future directions
Early aspects: aspect-oriented requirements engineering and architecture design
This paper reports on the third Early Aspects: Aspect-Oriented Requirements Engineering and Architecture Design Workshop, which has been held in Lancaster, UK, on March 21, 2004. The workshop included a presentation session and working sessions in which the particular topics on early aspects were discussed. The primary goal of the workshop was to focus on challenges to defining methodical software development processes for aspects from early on in the software life cycle and explore the potential of proposed methods and techniques to scale up to industrial applications
Use of nonintrusive sensor-based information and communication technology for real-world evidence for clinical trials in dementia
Cognitive function is an important end point of treatments in dementia clinical trials. Measuring cognitive function by standardized tests, however, is biased toward highly constrained environments (such as hospitals) in selected samples. Patient-powered real-world evidence using information and communication technology devices, including environmental and wearable sensors, may help to overcome these limitations. This position paper describes current and novel information and communication technology devices and algorithms to monitor behavior and function in people with prodromal and manifest stages of dementia continuously, and discusses clinical, technological, ethical, regulatory, and user-centered requirements for collecting real-world evidence in future randomized controlled trials. Challenges of data safety, quality, and privacy and regulatory requirements need to be addressed by future smart sensor technologies. When these requirements are satisfied, these technologies will provide access to truly user relevant outcomes and broader cohorts of participants than currently sampled in clinical trials
An Adaptive Design Methodology for Reduction of Product Development Risk
Embedded systems interaction with environment inherently complicates
understanding of requirements and their correct implementation. However,
product uncertainty is highest during early stages of development. Design
verification is an essential step in the development of any system, especially
for Embedded System. This paper introduces a novel adaptive design methodology,
which incorporates step-wise prototyping and verification. With each adaptive
step product-realization level is enhanced while decreasing the level of
product uncertainty, thereby reducing the overall costs. The back-bone of this
frame-work is the development of Domain Specific Operational (DOP) Model and
the associated Verification Instrumentation for Test and Evaluation, developed
based on the DOP model. Together they generate functionally valid test-sequence
for carrying out prototype evaluation. With the help of a case study 'Multimode
Detection Subsystem' the application of this method is sketched. The design
methodologies can be compared by defining and computing a generic performance
criterion like Average design-cycle Risk. For the case study, by computing
Average design-cycle Risk, it is shown that the adaptive method reduces the
product development risk for a small increase in the total design cycle time.Comment: 21 pages, 9 figure
CHORUS Deliverable 2.2: Second report - identification of multi-disciplinary key issues for gap analysis toward EU multimedia search engines roadmap
After addressing the state-of-the-art during the first year of Chorus and establishing the existing landscape in
multimedia search engines, we have identified and analyzed gaps within European research effort during our second year.
In this period we focused on three directions, notably technological issues, user-centred issues and use-cases and socio-
economic and legal aspects. These were assessed by two central studies: firstly, a concerted vision of functional breakdown
of generic multimedia search engine, and secondly, a representative use-cases descriptions with the related discussion on
requirement for technological challenges. Both studies have been carried out in cooperation and consultation with the
community at large through EC concertation meetings (multimedia search engines cluster), several meetings with our
Think-Tank, presentations in international conferences, and surveys addressed to EU projects coordinators as well as
National initiatives coordinators. Based on the obtained feedback we identified two types of gaps, namely core
technological gaps that involve research challenges, and “enablers”, which are not necessarily technical research
challenges, but have impact on innovation progress. New socio-economic trends are presented as well as emerging legal
challenges
Proteomics for rejection diagnosis in renal transplant patients: where are we now?
Rejection is one of the key factors that determine the long-term allograft function and survival in renal transplant patients. Reliable and timely diagnosis is important to treat rejection as early as possible. Allograft biopsies are not suitable for continuous monitoring of rejection. Thus, there is an unmet need for non-invasive methods to diagnose acute and chronic rejection. Proteomics in urine and blood samples has been explored for this purpose in 29 studies conducted since 2003. This review describes the different proteomic approaches and summarizes the results from the studies that examined proteomics for the rejection diagnoses. The potential limitations and open questions in establishing proteomic markers for rejection are discussed, including ongoing trials and future challenges to this topic
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