62,588 research outputs found
Deep Learning in Cardiology
The medical field is creating large amount of data that physicians are unable
to decipher and use efficiently. Moreover, rule-based expert systems are
inefficient in solving complicated medical tasks or for creating insights using
big data. Deep learning has emerged as a more accurate and effective technology
in a wide range of medical problems such as diagnosis, prediction and
intervention. Deep learning is a representation learning method that consists
of layers that transform the data non-linearly, thus, revealing hierarchical
relationships and structures. In this review we survey deep learning
application papers that use structured data, signal and imaging modalities from
cardiology. We discuss the advantages and limitations of applying deep learning
in cardiology that also apply in medicine in general, while proposing certain
directions as the most viable for clinical use.Comment: 27 pages, 2 figures, 10 table
Inference of stochastic nonlinear oscillators with applications to physiological problems
A new method of inferencing of coupled stochastic nonlinear oscillators is
described. The technique does not require extensive global optimization,
provides optimal compensation for noise-induced errors and is robust in a broad
range of dynamical models. We illustrate the main ideas of the technique by
inferencing a model of five globally and locally coupled noisy oscillators.
Specific modifications of the technique for inferencing hidden degrees of
freedom of coupled nonlinear oscillators is discussed in the context of
physiological applications.Comment: 11 pages, 10 figures, 2 tables Fluctuations and Noise 2004, SPIE
Conference, 25-28 May 2004 Gran Hotel Costa Meloneras Maspalomas, Gran
Canaria, Spai
Early hospital mortality prediction using vital signals
Early hospital mortality prediction is critical as intensivists strive to
make efficient medical decisions about the severely ill patients staying in
intensive care units. As a result, various methods have been developed to
address this problem based on clinical records. However, some of the laboratory
test results are time-consuming and need to be processed. In this paper, we
propose a novel method to predict mortality using features extracted from the
heart signals of patients within the first hour of ICU admission. In order to
predict the risk, quantitative features have been computed based on the heart
rate signals of ICU patients. Each signal is described in terms of 12
statistical and signal-based features. The extracted features are fed into
eight classifiers: decision tree, linear discriminant, logistic regression,
support vector machine (SVM), random forest, boosted trees, Gaussian SVM, and
K-nearest neighborhood (K-NN). To derive insight into the performance of the
proposed method, several experiments have been conducted using the well-known
clinical dataset named Medical Information Mart for Intensive Care III
(MIMIC-III). The experimental results demonstrate the capability of the
proposed method in terms of precision, recall, F1-score, and area under the
receiver operating characteristic curve (AUC). The decision tree classifier
satisfies both accuracy and interpretability better than the other classifiers,
producing an F1-score and AUC equal to 0.91 and 0.93, respectively. It
indicates that heart rate signals can be used for predicting mortality in
patients in the ICU, achieving a comparable performance with existing
predictions that rely on high dimensional features from clinical records which
need to be processed and may contain missing information.Comment: 11 pages, 5 figures, preprint of accepted paper in IEEE&ACM CHASE
2018 and published in Smart Health journa
A Review of Atrial Fibrillation Detection Methods as a Service
Atrial Fibrillation (AF) is a common heart arrhythmia that often goes undetected, and even if it is detected, managing the condition may be challenging. In this paper, we review how the RR interval and Electrocardiogram (ECG) signals, incorporated into a monitoring system, can be useful to track AF events. Were such an automated system to be implemented, it could be used to help manage AF and thereby reduce patient morbidity and mortality. The main impetus behind the idea of developing a service is that a greater data volume analyzed can lead to better patient outcomes. Based on the literature review, which we present herein, we introduce the methods that can be used to detect AF efficiently and automatically via the RR interval and ECG signals. A cardiovascular disease monitoring service that incorporates one or multiple of these detection methods could extend event observation to all times, and could therefore become useful to establish any AF occurrence. The development of an automated and efficient method that monitors AF in real time would likely become a key component for meeting public health goals regarding the reduction of fatalities caused by the disease. Yet, at present, significant technological and regulatory obstacles remain, which prevent the development of any proposed system. Establishment of the scientific foundation for monitoring is important to provide effective service to patients and healthcare professionals
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A review of machine learning techniques in photoplethysmography for the non-invasive cuff-less measurement of blood pressure
Hypertension or high blood pressure is a leading cause of death throughout the world and a critical factor for increasing the risk of serious diseases, including cardiovascular diseases such as stroke and heart failure. Blood pressure is a primary vital sign that must be monitored regularly for the early detection, prevention and treatment of cardiovascular diseases. Traditional blood pressure measurement techniques are either invasive or cuff-based, which are impractical, intermittent, and uncomfortable for patients. Over the past few decades, several indirect approaches using photoplethysmogram (PPG) have been investigated, namely, pulse transit time, pulse wave velocity, pulse arrival time and pulse wave analysis, in an effort to utilise PPG for estimating blood pressure. Recent advancements in signal processing techniques, including machine learning and artificial intelligence, have also opened up exciting new horizons for PPG-based cuff less and continuous monitoring of blood pressure. Such a device will have a significant and transformative impact in monitoring patients’ vital signs, especially those at risk of cardiovascular disease. This paper provides a comprehensive review for non-invasive cuff-less blood pressure estimation using the PPG approach along with their challenges and limitations
Protocol of the SOMNIA project : an observational study to create a neurophysiological database for advanced clinical sleep monitoring
Introduction Polysomnography (PSG) is the primary tool for sleep monitoring and the diagnosis of sleep disorders. Recent advances in signal analysis make it possible to reveal more information from this rich data source. Furthermore, many innovative sleep monitoring techniques are being developed that are less obtrusive, easier to use over long time periods and in the home situation. Here, we describe the methods of the Sleep and Obstructive Sleep Apnoea Monitoring with Non-Invasive Applications (SOMNIA) project, yielding a database combining clinical PSG with advanced unobtrusive sleep monitoring modalities in a large cohort of patients with various sleep disorders. The SOMNIA database will facilitate the validation and assessment of the diagnostic value of the new techniques, as well as the development of additional indices and biomarkers derived from new and/or traditional sleep monitoring methods.
Methods and analysis We aim to include at least 2100 subjects (both adults and children) with a variety of sleep disorders who undergo a PSG as part of standard clinical care in a dedicated sleep centre. Full-video PSG will be performed according to the standards of the American Academy of Sleep Medicine. Each recording will be supplemented with one or more new monitoring systems, including wrist-worn photoplethysmography and actigraphy, pressure sensing mattresses, multimicrophone recording of respiratory sounds including snoring, suprasternal pressure monitoring and multielectrode electromyography of the diaphragm
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