Defeasible Reasoning in SROEL: from Rational Entailment to Rational Closure

In this work we study a rational extension $SROEL^R T$ of the low complexity description logic SROEL, which underlies the OWL EL ontology language. The extension involves a typicality operator T, whose semantics is based on Lehmann and Magidor's ranked models and allows for the definition of defeasible inclusions. We consider both rational entailment and minimal entailment. We show that deciding instance checking under minimal entailment is in general $\Pi^P_2$-hard, while, under rational entailment, instance checking can be computed in polynomial time. We develop a Datalog calculus for instance checking under rational entailment and exploit it, with stratified negation, for computing the rational closure of simple KBs in polynomial time.Comment: Accepted for publication on Fundamenta Informatica

Automatically selecting patients for clinical trials with justifications

Clinical trials are human research studies that are used to evaluate the effectiveness of a surgical, medical, or behavioral intervention. They have been widely used by researchers to determine whether a new treatment, such as a new medication, is safe and effective in humans. A clinical trial is frequently performed to determine whether a new treatment is more successful than the current treatment or has less harmful side effects. However, clinical trials have a high failure rate. One method applied is to find patients based on patient records. Unfortunately, this is a difficult process. This is because this process is typically performed manually, making it time-consuming and error-prone. Consequently, clinical trial deadlines are often missed, and studies do not move forward. Time can be a determining factor for success. Therefore, it would be advantageous to have automatic support in this process. Since it is also important to be able to validate whether the patients were selected correctly for the trial, avoiding eventual health problems, it would be important to have a mechanism to present justifications for the selected patients. In this dissertation, we present one possible solution to solve the problem of patient selection for clinical trials. We developed the necessary algorithms and created a simple and intuitive web application that features the selection of patients for clinical trials automatically. This was achieved by combining knowledge expressed in different formalisms. We integrated medical knowledge using ontologies, with criteria that were expressed using nonmonotonic rules. To address the validation procedure automatically, we developed a mechanism that generates the justifications for each selection together with the results of the patients who were selected. In the end, it is expected that a user can easily enter a set of trial criteria, and the application will generate the results of the selected patients and their respective justifications, based on the criteria inserted, medical information and a database of patient information.Os ensaios clínicos são estudos de pesquisa em humanos, utilizados para avaliar a eficácia de uma intervenção cirúrgica, médica ou comportamental. Estes estudos, têm sido amplamente utilizados pelos investigadores para determinar se um novo tratamento, como é o caso de um novo medicamento, é seguro e eficaz em humanos. Um ensaio clínico é realizado frequentemente, para determinar se um novo tratamento tem mais sucesso do que o tratamento atual ou se tem menos efeitos colaterais prejudiciais. No entanto, os ensaios clínicos têm uma taxa de insucesso alta. Um método aplicado é encontrar pacientes com base em registos. Infelizmente, este é um processo difícil. Isto deve-se ao facto deste processo ser normalmente realizado à mão, o que o torna demorado e propenso a erros. Consequentemente, o prazo dos ensaios clínicos é muitas vezes ultrapassado e os estudos acabam por não avançar. O tempo pode ser por vezes um fator determinante para o sucesso. Seria então vantajoso ter algum apoio automático neste processo. Visto que também seria importante validar se os pacientes foram selecionados corretamente para o ensaio, evitando até eventuais problemas de saúde, seria importante ter um mecanismo que apresente justificações para os pacientes selecionados. Nesta dissertação, apresentamos uma possível solução para resolver o problema da seleção de pacientes para ensaios clínicos, através da criação de uma aplicação web, intuitiva e fácil de utilizar, que apresenta a seleção de pacientes para ensaios clínicos de forma automática. Isto foi alcançado através da combinação de conhecimento expresso em diferentes formalismos. Integrámos o conhecimento médico usando ontologias, com os critérios que serão expressos usando regras não monotónicas. Para tratar do processo de validação, desenvolvemos um mecanismo que gera justificações para cada seleção juntamente com os resultados dos pacientes selecionados. No final, é esperado que o utilizador consiga inserir facilmente um conjunto de critérios de seleção, e a aplicação irá gerar os resultados dos pacientes selecionados e as respetivas justificações, com base nos critérios inseridos, informações médicas e uma base de dados com informações dos pacientes

Bounded Rationality and Heuristics in Humans and in Artificial Cognitive Systems

In this paper I will present an analysis of the impact that the notion of “bounded rationality”, introduced by Herbert Simon in his book “Administrative Behavior”, produced in the field of Artificial Intelligence (AI). In particular, by focusing on the field of Automated Decision Making (ADM), I will show how the introduction of the cognitive dimension into the study of choice of a rational (natural) agent, indirectly determined - in the AI field - the development of a line of research aiming at the realisation of artificial systems whose decisions are based on the adoption of powerful shortcut strategies (known as heuristics) based on “satisficing” - i.e. non optimal - solutions to problem solving. I will show how the “heuristic approach” to problem solving allowed, in AI, to face problems of combinatorial complexity in real-life situations and still represents an important strategy for the design and implementation of intelligent systems

Current and Future Challenges in Knowledge Representation and Reasoning

Knowledge Representation and Reasoning is a central, longstanding, and active area of Artificial Intelligence. Over the years it has evolved significantly; more recently it has been challenged and complemented by research in areas such as machine learning and reasoning under uncertainty. In July 2022 a Dagstuhl Perspectives workshop was held on Knowledge Representation and Reasoning. The goal of the workshop was to describe the state of the art in the field, including its relation with other areas, its shortcomings and strengths, together with recommendations for future progress. We developed this manifesto based on the presentations, panels, working groups, and discussions that took place at the Dagstuhl Workshop. It is a declaration of our views on Knowledge Representation: its origins, goals, milestones, and current foci; its relation to other disciplines, especially to Artificial Intelligence; and on its challenges, along with key priorities for the next decade

A DISCREPANCY-BASED MEASUREMENT APPROACH FOR DATA INTEGRATION

This paper presents a measurement instrument for diagnosing the level of data integration at the organization and organization subunit levels. Incorporating consideration for specific theoretical properties related to data integration into its design, the measurement instrument relies on a discrepancy (or gap) measure to adequately account for these properties. Data from forty-eight organizations of the Group Insurance industry are used to test the reliability and validity of the measurement instrument. The results suggest that the discrepancy measure, based on the difference between respondents' ideal (i.e. normative) and actual estimates of data integration, appears to be a valid indicator of data integration. However the efficacy of using a discrepancy measure, over the simpler use of its parts, must be considered in light of practical and theoretical considerations.Information Systems Working Papers Serie

Basic characteristics to achieve common sense reasoning

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Information Flow within Relational Multi-context Systems

Publication in progressMulti-context systems (MCSs) are an important framework for heterogeneous combinations of systems within the Semantic Web. In this paper, we propose generic constructions to achieve specific forms of interaction in a principled way, and systematize some useful techniques to work with ontologies within an MCS. All these mechanisms are presented in the form of general-purpose design patterns. Their study also suggests new ways in which this framework can be further extended.This work was partially supported by Fundação para a Ciência e Tecnologia under contract PEst- OE/EEI/UI0434/2011

OWL Reasoners still useable in 2023

In a systematic literature and software review over 100 OWL reasoners/systems were analyzed to see if they would still be usable in 2023. This has never been done in this capacity. OWL reasoners still play an important role in knowledge organisation and management, but the last comprehensive surveys/studies are more than 8 years old. The result of this work is a comprehensive list of 95 standalone OWL reasoners and systems using an OWL reasoner. For each item, information on project pages, source code repositories and related documentation was gathered. The raw research data is provided in a Github repository for anyone to use