90,155 research outputs found

    Health Information Science: 7th International Conference, HIS 2018, Cairns, QLD, Australia, October 5–7, 2018, Proceedings

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    [Extract] The International Conference Series on Health Information Science (HIS) provides a forum for disseminating and exchanging multidisciplinary research results in computer science/information technology and health science and services. It covers all aspects of health information sciences and systems that support health information management and health service delivery. The 7th International Conference on Health Information Science (HIS 2018) was held in Cairns, Queensland, Australia, during October 5–7, 2018. Founded in April 2012 as the International Conference on Health Information Science and Their Applications, the conference continues to grow to include an ever-broader scope of activities. The main goal of these events is to provide international scientific forums for researchers to exchange new ideas in a number of fields that interact in depth through discussions with their peers from around the world. The scope of the conference includes: (1) medical/health/biomedicine information resources, such as patient medical records, devices and equipments, software and tools to capture, store, retrieve, process, analyze, and optimize the use of information in the health domain; (2) data management, data mining, and knowledge discovery, all of which play a key role in decision-making, management of public health, examination of standards, privacy and security issues; (3) computer visualization and artificial intelligence for computer-aided diagnosis; and (4) development of new architectures and applications for health information systems

    Knowledge Discovery in the SCADA Databases Used for the Municipal Power Supply System

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    This scientific paper delves into the problems related to the develop-ment of intellectual data analysis system that could support decision making to manage municipal power supply services. The management problems of mu-nicipal power supply system have been specified taking into consideration modern tendencies shown by new technologies that allow for an increase in the energy efficiency. The analysis findings of the system problems related to the integrated computer-aided control of the power supply for the city have been given. The consideration was given to the hierarchy-level management decom-position model. The objective task targeted at an increase in the energy effi-ciency to minimize expenditures and energy losses during the generation and transportation of energy carriers to the Consumer, the optimization of power consumption at the prescribed level of the reliability of pipelines and networks and the satisfaction of Consumers has been defined. To optimize the support of the decision making a new approach to the monitoring of engineering systems and technological processes related to the energy consumption and transporta-tion using the technologies of geospatial analysis and Knowledge Discovery in databases (KDD) has been proposed. The data acquisition for analytical prob-lems is realized in the wireless heterogeneous medium, which includes soft-touch VPN segments of ZigBee technology realizing the 6LoWPAN standard over the IEEE 802.15.4 standard and also the segments of the networks of cellu-lar communications. JBoss Application Server is used as a server-based plat-form for the operation of the tools used for the retrieval of data collected from sensor nodes, PLC and energy consumption record devices. The KDD tools are developed using Java Enterprise Edition platform and Spring and ORM Hiber-nate technologies

    The Journal of Computer-Aided Molecular Design: a bibliometric note

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    Summarizes the articles in, and the citations to, volumes 2-24 of the Journal of Computer-Aided Molecular Design. The citations to the journal come from almost 2000 different sources that span a very wide range of academic subjects, with the most heavily cited articles being descriptions of software systems and of computational methods

    The benefits of in silico modeling to identify possible small-molecule drugs and their off-target interactions

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    Accepted for publication in a future issue of Future Medicinal Chemistry.The research into the use of small molecules as drugs continues to be a key driver in the development of molecular databases, computer-aided drug design software and collaborative platforms. The evolution of computational approaches is driven by the essential criteria that a drug molecule has to fulfill, from the affinity to targets to minimal side effects while having adequate absorption, distribution, metabolism, and excretion (ADME) properties. A combination of ligand- and structure-based drug development approaches is already used to obtain consensus predictions of small molecule activities and their off-target interactions. Further integration of these methods into easy-to-use workflows informed by systems biology could realize the full potential of available data in the drug discovery and reduce the attrition of drug candidates.Peer reviewe

    Research and Education in Computational Science and Engineering

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    Over the past two decades the field of computational science and engineering (CSE) has penetrated both basic and applied research in academia, industry, and laboratories to advance discovery, optimize systems, support decision-makers, and educate the scientific and engineering workforce. Informed by centuries of theory and experiment, CSE performs computational experiments to answer questions that neither theory nor experiment alone is equipped to answer. CSE provides scientists and engineers of all persuasions with algorithmic inventions and software systems that transcend disciplines and scales. Carried on a wave of digital technology, CSE brings the power of parallelism to bear on troves of data. Mathematics-based advanced computing has become a prevalent means of discovery and innovation in essentially all areas of science, engineering, technology, and society; and the CSE community is at the core of this transformation. However, a combination of disruptive developments---including the architectural complexity of extreme-scale computing, the data revolution that engulfs the planet, and the specialization required to follow the applications to new frontiers---is redefining the scope and reach of the CSE endeavor. This report describes the rapid expansion of CSE and the challenges to sustaining its bold advances. The report also presents strategies and directions for CSE research and education for the next decade.Comment: Major revision, to appear in SIAM Revie

    11th German Conference on Chemoinformatics (GCC 2015) : Fulda, Germany. 8-10 November 2015.

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