Digital games for people with Autism Spectrum Disorders (ASD): a systematic review

Individuos com transtornos do espectro do autismo (TEA) possuem desenvolvimento atipico nas areas cognitiva ou de aprendizagem, comunicacao e interacao social, deteccao e trato de emocoes, coordenacao motora e concentracao. O desenvolvimento de tecnologias assistivas e fundamental para melhorar a qualidade de vida destes individuos. Este estudo faz uma revisao sistematica da literatura com foco em jogos digitais usados como tecnologias assistivas para individuos com TEA. Fazendo uso da base digital IEEE Xplore, foram pesquisados estudos que continham o termo game em conjunto com termos relacionados ao TEA. A partir da busca foram encontradas 193 ocorrencias do conjunto de termos. Os artigos foram lidos e analisados, sendo selecionados os estudos que tratam de jogos digitais com foco em individuos com TEA. Foram excluidos da selecao jogos que fazem uso unicamente de hardwares especificos e que nao apresentam funcao de tecnología assistiva. Como resultado final deste estudo foram selecionados 62 artigos neste contexto, sendo que todos apresentam resultados positivos quanto ao uso dos jogos digitais na melhoria das capacidades das pessoas com TEA. Desta forma, e possivel verificar a consistencia de tal abordagem, encorajando a continuidade das pesquisas e do desenvolvimento de jogos digitais com foco em tecnología assistiva para pessoas com TEA.Individuals with autism spectrum disorders (ASD) have atypical development in the areas of cognition or learning, communication and social interaction, detection and treatment of emotions, motor coordination and concentration. The development of assistive technologies is critical because they help to better the quality of life of these individuals. This study makes a systematic review of the literature focusing on digital games used as assistive technologies for individuals with ASD. Using the IEEE Xplore digital base, studies were conducted that contained the term "game" in conjunction with terms related to ASD. From the search were found 193 occurrences of the set of terms were found. The articles were read and analyzed, being the studies that deal with digital games focused on individuals with ASD. Games that only use specific hardware and not have the function of assistive technology were excluded from the selection. As a final result of this study, 62 articles were selected in this context, all of which present positive results regarding the use of digital games in improving the abilities of people with ASD. In this way, it is possible to verify the consistency of such an approach, encouraging the continuity of research and the development of digital games with a focus on assistive technology for people with ASD.Facultad de Informátic

As aplicações de TLBL podem melhorar os aspectos do TEA relacionados a distúrbios no microbioma intestinal, atividade mitocondrial e função da rede neural

Autism Spectrum Disorder constitutes a complex, elaborate, and diverse condition at a developmental, biological, and neurophysiological level. It is recognized primarily by the behavioral manifestations of the individual in communication, social interaction, and by extension in his cognitive development and adaptation to society as a whole. A wide range of studies have linked the pathophysiology of autism to dysfunctional elements in the development and function of mitochondria, cells, neurons, and the gastrointestinal microbiome. Low Light Laser Therapy (LLLT) is an innovative, emerging, non-invasive treatment method. It utilizes low levels of red light/near-infrared light positively affecting biological and pathological processes of the body by enhancing cellular, mitochondrial stimulation, neurogenesis, synaptogenesis, and immune system development, regulating the gut microbiome's function. The retrospective literature review focuses on the possibility of effective use of the method in autism. According to the literature, LLLT does not have many applications in patients with ASD and is still in the early stages of its use in the disorder. However, the results of the studies highlight its therapeutic effect in several areas related to the disease, pointing out that it is a promising therapeutic approach for the evolution of autism in the future.El Trastorno del Espectro Autista constituye una condición compleja, elaborada y diversa a nivel del desarrollo, biológico y neurofisiológico. Se reconoce principalmente por las manifestaciones conductuales del individuo en la comunicación, la interacción social y por extensión en su desarrollo cognitivo y adaptación a la sociedad en su conjunto. Una amplia gama de estudios ha relacionado la fisiopatología del autismo con elementos disfuncionales en el desarrollo y función de las mitocondrias, las células, las neuronas y el microbioma gastrointestinal. La terapia con láser con poca luz (LLLT) es un método de tratamiento innovador, emergente y no invasivo. Utiliza niveles bajos de luz roja/luz infrarroja cercana que afectan positivamente los procesos biológicos y patológicos del cuerpo al mejorar la estimulación celular, mitocondrial, la neurogénesis, la sinaptogénesis y el desarrollo del sistema inmunológico, regulando la función del microbioma intestinal. La revisión retrospectiva de la literatura se centra en la posibilidad de un uso eficaz del método en el autismo. Según la literatura, la LLLT no tiene muchas aplicaciones en pacientes con TEA y aún se encuentra en las primeras etapas de su uso en el trastorno. Sin embargo, los resultados de los estudios destacan su efecto terapéutico en varias áreas relacionadas con la enfermedad, señalando que es un enfoque terapéutico prometedor para la evolución del autismo en el futuro.O Transtorno do Espectro Autista constitui uma condição complexa, elaborada e diversificada em nível de desenvolvimento, biológico e neurofisiológico. É reconhecida principalmente pelas manifestações comportamentais do indivíduo na comunicação, interação social e, por extensão, em seu desenvolvimento cognitivo e adaptação à sociedade como um todo. Uma ampla gama de estudos ligou a fisiopatologia do autismo a elementos disfuncionais no desenvolvimento e função das mitocôndrias, células, neurônios e do microbioma gastrointestinal. Terapia a laser de baixa luminosidade (TLBL) é um método de tratamento inovador, emergente e não invasivo. Ele utiliza baixos níveis de luz vermelha/luz quase infravermelha (NIR) afetando positivamente os processos biológicos e patológicos do corpo, melhorando a estimulação celular, mitocondrial, neurogênese, sinaptogênese e desenvolvimento do sistema imunológico, regulando a função do microbioma intestinal. A revisão retrospectiva da literatura enfoca a possibilidade de uso efetivo do método no autismo. De acordo com a literatura, a TLBL não tem muitas aplicações em pacientes com TEA e ainda está em estágios iniciais de seu uso no transtorno. No entanto, os resultados dos estudos destacam seu efeito terapêutico em diversas áreas relacionadas à doença, apontando que é uma abordagem terapêutica promissora para a evolução do autismo no futuro

Improving social and behavioural functioning in children with autism spectrum disorder: a videogame skills based feasibility trial

This thesis assessed the feasibility of using specifically designed video-games to improve functioning in children with autism spectrum disorder. The findings provide preliminary evidence supporting the use of Whiz Kid Games (a freely accessible, online, video-game based intervention) for improving both social and behavioural functioning in children aged 6-12 who have been diagnosed with autism.<br /

Social and Non-Social Reward Processing in Autism and Autistic Traits

Belohnungen sind im Leben des Menschen von enormer Bedeutung. Es wurde vermutet, dass die zentralen sozialen Schwierigkeiten bei Autismus-Spektrum-Störungen (ASS) auf eine verminderte Reaktionsfähigkeit auf spezifische soziale Belohnungen zurückzuführen sein könnten. Die Literatur zu diesem Thema ist jedoch nicht schlüssig. Diese Dissertation umfasst vier Studien, die die Reaktionsfähigkeit auf soziale und nicht-soziale Belohnungen unter besonderer Berücksichtigung von ASS und autistischen Merkmalen untersuchen. In den Studien 1 und 2 wurden neuronale (ereigniskorrelierte Potenziale), autonome (Pupillengröße) und verhaltensbezogene (Selbstberichte und Reaktionszeiten) Indizes der Reaktion auf soziale und nicht-soziale Belohnungen bei Personen mit ASC sowie mit ausgeprägten und geringen autistischen Merkmalen untersucht. Wir stellten fest, dass ein höheres Maß an autistischen Merkmalen bei klinischen ASS und in der Allgemeinbevölkerung mit einer verstärkten neuronalen und autonomen Verarbeitung, typischen Leistungen und einer geringeren selbstberichteten Belohnungssensitivität verbunden war. Studie 3 untersuchte die Auswirkungen von sozialer Vertrautheit und Belohnungskontext auf die Pupillenreaktionen. Die Ergebnisse deuten darauf hin, dass der Belohnungswert eines positiven Reizes bei vertrauten Gesichtern höher ist und von der Assoziation zwischen Handlung und Ergebnis abhängt. Studie 4 ist eine theoretische Perspektive zum Verständnis der Multidimensionalität von Belohnungen und zum Umgang damit. In allen Studien konnte ich nachweisen, dass das Belohnungsverhalten von ASS vielfältig und atypisch, aber nicht defizitär ist. Außerdem schlage ich eine Definition von Belohnung vor, die sie von einem rein positiven Stimulus unterscheidet. Schließlich erörtere ich diese Arbeit im breiteren Rahmen der sozialneuropsychologischen Forschung und zeige Möglichkeiten auf, wie sie in künftigen Studien weiter verbessert werden kann.Rewards are immensely important in human lives. It has been suggested that the core social difficulties in autism spectrum conditions (ASC) may stem from lowered responsiveness to specifically social rewards. However, the literature on this topic is inconclusive. This dissertation includes four studies investigating reward responsiveness to social and non-social rewards with particular focus on ASC and autistic traits. Studies 1 and 2 investigated neuronal (event-related potentials), autonomic (pupil sizes) and behavioural (self-reports and reaction times) indexes of responsiveness to social and non-social rewards in individuals with ASC, and with high and low autistic traits. We observed that higher levels of autistic traits in clinical ASC and in the general population were linked to enhanced neuronal and autonomic processing, typical performance, and decreased self-reported reward sensitivity. Study 3 investigated the effects of social familiarity and rewarding context on pupillary responses. The results indicated that the reward value of a positive stimulus is higher for more familiar faces and depends on action-outcome associations. Study 4 is a theoretical perspective on understanding and working with multidimensionality of rewards. Across all studies, I provide evidence for multifaceted and atypical, but not deficient, reward responsiveness in ASC. Further, I propose a definition of reward which differentiates it from a merely positive stimulus. Finally, I discuss this work in the broader framework of social neuropsychology research and identify the ways in which it can be further improved in future studies

Patient centric intervention for children with high functioning autism spectrum disorder. Can ICT solutions improve the state of the art ?

In my PhD research we developed an integrated technological platform for the acquisition of neurophysiologic signals in a semi-naturalistic setting where children are free to move around, play with different objects and interact with the examiner. The interaction with the examiner rather than with a screen is another very important feature of the present research, and allows recreating a more real situation with social interactions and cues. In this paradigm, we can assume that the signals acquired from the brain and the autonomic system, are much more similar to what is generated while the child interacts in common life situations. This setting, with a relatively simple technical implementation, can be considered as one step towards a more behaviorally driven analysis of neurophysiologic activity. Within the context of a pilot open trial, we showed the feasibility of the technological platform applied to the classical intervention solutions for the autism. We found that (1) the platform was useful during both children-therapist interaction at hospital as well as children-parents interaction at home, (2) tailored intervention was compatible with at home use and non-professional therapist/parents. Going back to the title of my thesis: 'Can ICT solution improve the state-of-the-art ?' the answer could be: 'Yes it can be an useful support for a skilled professional in the field of autis

Interactive sonification to assist children with autism during motor therapeutic interventions

Interactive sonification is an effective tool used to guide individuals when practicing movements. Little research has shown the use of interactive sonification in supporting motor therapeutic interventions for children with autism who exhibit motor impairments. The goal of this research is to study if children with autism understand the use of interactive sonification during motor therapeutic interventions, its potential impact of interactive sonification in the development of motor skills in children with autism, and the feasibility of using it in specialized schools for children with autism. We conducted two deployment studies in Mexico using Go-with-the-Flow, a framework to sonify movements previously developed for chronic pain rehabilitation. In the first study, six children with autism were asked to perform the forward reach and lateral upper-limb exercises while listening to three different sound structures (i.e., one discrete and two continuous sounds). Results showed that children with autism exhibit awareness about the sonification of their movements and engage with the sonification. We then adapted the sonifications based on the results of the first study, for motor therapy of children with autism. In the next study, nine children with autism were asked to perform upper-limb lateral, cross-lateral, and push movements while listening to five different sound structures (i.e., three discrete and two continues) designed to sonify the movements. Results showed that discrete sound structures engage the children in the performance of upper-limb movements and increase their ability to perform the movements correctly. We finally propose design considerations that could guide the design of projects related to interactive sonification

The meanings of the 'struggle/fight metaphor' in the special needs domain: the experiences of practitioners and parents of children with high functioning autism spectrum conditions

The special needs domain has long been recognised as problematic and adversarial. Much research has focused on areas of contention, such as the relationships between parents and practitioners, especially in educational settings, or on problems within the structure and operation of the domain. This study adopts a whole system approach in combining discussion of the structural basis of tension within the domain with an investigation of how both parents and practitioners describe, experience and respond to tensions within the special needs domain; such tensions being viewed as facets of the 'struggle' and 'fight' metaphor. Whole systems approaches are derived from the systems discipline, which developed initially out of the nineteenth century interest in organic and engineering systems, but more recently has focused on organisational and inter-organisational arrangements, including the part people play in enabling or disabling such arrangements. It is a strongly interdisciplinary approach more commonly found in organisational studies than in the social sciences more generally. Fifteen practitioners, from health and education settings, and twelve parents of children and young people with diagnoses of high functioning autism spectrum conditions participated in the study. The participants' stories of their experiences of the special needs domain were collected using a narrative inquiry approach. The data was analysed using concepts and theoretical frameworks derived from the work of Pierre Bourdieu, Uri Bronfenbrenner and Charles Wright Mills. An exploration of the influences shaping the special needs domain revealed a number of areas of unresolved tension, some of which result in tensions for those involved in the domain such as can be described as 'fight', and some of which might be addressed by structural changes to the systems comprising the special needs domain such as those envisaged in forthcoming legislation. However importantly the empirical study found that many tensions and struggles experienced by both parents and practitioners did not emanate from the structures of the domain and therefore were unlikely to be amenable to structural changes. Parents 'struggle' to maintain their identity as 'good' parents, to acquire information and to navigate the system in order to access services and resources. Practitioners experience conflict as they seek to access information and training, engage in the complex choreography of cooperating and collaborating in interagency and interprofessional working and endeavour to harmonise their professional practice with agency and public policy priorities. The thesis concludes with a brief discussion of the relationship between whole system approaches and other interdisciplinary approaches to investigating complex problems in the human sciences. It is suggested that systems diagramming techniques such as systems mapping and rich pictures are useful additions to the sociologist's toolkit