Disentangling causal webs in the brain using functional Magnetic Resonance Imaging: A review of current approaches

In the past two decades, functional Magnetic Resonance Imaging has been used to relate neuronal network activity to cognitive processing and behaviour. Recently this approach has been augmented by algorithms that allow us to infer causal links between component populations of neuronal networks. Multiple inference procedures have been proposed to approach this research question but so far, each method has limitations when it comes to establishing whole-brain connectivity patterns. In this work, we discuss eight ways to infer causality in fMRI research: Bayesian Nets, Dynamical Causal Modelling, Granger Causality, Likelihood Ratios, LiNGAM, Patel's Tau, Structural Equation Modelling, and Transfer Entropy. We finish with formulating some recommendations for the future directions in this area

Detecting and Explaining Causes From Text For a Time Series Event

Explaining underlying causes or effects about events is a challenging but valuable task. We define a novel problem of generating explanations of a time series event by (1) searching cause and effect relationships of the time series with textual data and (2) constructing a connecting chain between them to generate an explanation. To detect causal features from text, we propose a novel method based on the Granger causality of time series between features extracted from text such as N-grams, topics, sentiments, and their composition. The generation of the sequence of causal entities requires a commonsense causative knowledge base with efficient reasoning. To ensure good interpretability and appropriate lexical usage we combine symbolic and neural representations, using a neural reasoning algorithm trained on commonsense causal tuples to predict the next cause step. Our quantitative and human analysis show empirical evidence that our method successfully extracts meaningful causality relationships between time series with textual features and generates appropriate explanation between them.Comment: Accepted at EMNLP 201

Identifying causal gateways and mediators in complex spatio-temporal systems

J.R. received support by the German National Academic Foundation (Studienstiftung), a Humboldt University Postdoctoral Fellowship, and the German Federal Ministry of Science and Education (Young Investigators Group CoSy-CC2, grant no. 01LN1306A). J.F.D. thanks the Stordalen Foundation and BMBF (project GLUES) for financial support. D.H. has been funded by grant ERC-CZ CORES LL-1201 of the Czech Ministry of Education. M.P. and N.J. received funding from the Czech Science Foundation project No. P303-14-02634S and from the Czech Ministry of Education, Youth and Sports, project No. DAAD-15-30. J.H. was supported by the Czech Science Foundation project GA13-23940S and Czech Health Research Council project NV15-29835A. We thank Mary Lindsey from the National Oceanic and Atmospheric Administration for her kind help with Fig. 4e. NCEP Reanalysis data provided by NOAA/OAR/ESRL PSD, Boulder, Colorado, USA, from their web site at http://www.esrl.noaa.gov/psd/.Peer reviewedPublisher PD