4,897 research outputs found

    A handheld high-sensitivity micro-NMR CMOS platform with B-field stabilization for multi-type biological/chemical assays

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    We report a micro-nuclear magnetic resonance (NMR) system compatible with multi-type biological/chemical lab-on-a-chip assays. Unified in a handheld scale (dimension: 14 x 6 x 11 cm³, weight: 1.4 kg), the system is capable to detect<100 pM of Enterococcus faecalis derived DNA from a 2.5 μL sample. The key components are a portable magnet (0.46 T, 1.25 kg) for nucleus magnetization, a system PCB for I/O interface, an FPGA for system control, a current driver for trimming the magnetic (B) field, and a silicon chip fabricated in 0.18 μm CMOS. The latter, integrated with a current-mode vertical Hall sensor and a low-noise readout circuit, facilitates closed-loop B-field stabilization (2 mT → 0.15 mT), which otherwise fluctuates with temperature or sample displacement. Together with a dynamic-B-field transceiver with a planar coil for micro-NMR assay and thermal control, the system demonstrates: 1) selective biological target pinpointing; 2) protein state analysis; and 3) solvent-polymer dynamics, suitable for healthcare, food and colloidal applications, respectively. Compared to a commercial NMR-assay product (Bruker mq-20), this platform greatly reduces the sample consumption (120x), hardware volume (175x), and weight (96x)

    A 65-nm CMOS Temperature-Compensated Mobility-Based Frequency reference for wireless sensor networks

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    For the first time, a temperature-compensated CMOS frequency reference based on the electron mobility in a MOS transistor is presented. Over the temperature range from -55°C to 125 °C, its frequency spread is less than ±0.5% after a two-point trim and less than ±2.7% after a one-point trim. These results make it suitable for use in Wireless Sensor Network nodes. Fabricated in a baseline 65-nm CMOS process, the 150 kHz frequency reference occupies 0.2 mm2 and draws 42.6 μA from a 1.2-V supply at room temperature.\ud \u

    An Ultra-Low-Power Oscillator with Temperature and Process Compensation for UHF RFID Transponder

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    This paper presents a 1.28MHz ultra-low-power oscillator with temperature and process compensation. It is very suitable for clock generation circuits used in ultra-high-frequency (UHF) radio-frequency identification (RFID) transponders. Detailed analysis of the oscillator design, including process and temperature compensation techniques are discussed. The circuit is designed using TSMC 0.18μm standard CMOS process and simulated with Spectre. Simulation results show that, without post-fabrication calibration or off-chip components, less than ±3% frequency variation is obtained from –40 to 85°C in three different process corners. Monte Carlo simulations have also been performed, and demonstrate a 3σ deviation of about 6%. The power for the proposed circuitry is only 1.18µW at 27°C

    Manipulating Fock states of a harmonic oscillator while preserving its linearity

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    We present a new scheme for controlling the quantum state of a harmonic oscillator by coupling it to an anharmonic multilevel system (MLS) with first to second excited state transition frequency on-resonance with the oscillator. In this scheme that we call "ef-resonant", the spurious oscillator Kerr non-linearity inherited from the MLS is very small, while its Fock states can still be selectively addressed via an MLS transition at a frequency that depends on the number of photons. We implement this concept in a circuit-QED setup with a microwave 3D cavity (the oscillator, with frequency 6.4 GHz and quality factor QO=2E-6) embedding a frequency tunable transmon qubit (the MLS). We characterize the system spectroscopically and demonstrate selective addressing of Fock states and a Kerr non-linearity below 350 Hz. At times much longer than the transmon coherence times, a non-linear cavity response with driving power is also observed and explained.Comment: 8 pages, 5 figure

    Quantum-to-Classical Transition in Cavity Quantum Electrodynamics

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    The quantum properties of electromagnetic, mechanical or other harmonic oscillators can be revealed by investigating their strong coherent coupling to a single quantum two level system in an approach known as cavity quantum electrodynamics (QED). At temperatures much lower than the characteristic energy level spacing the observation of vacuum Rabi oscillations or mode splittings with one or a few quanta asserts the quantum nature of the oscillator. Here, we study how the classical response of a cavity QED system emerges from the quantum one when its thermal occupation -- or effective temperature -- is raised gradually over 5 orders of magnitude. In this way we explore in detail the continuous quantum-to-classical crossover and demonstrate how to extract effective cavity field temperatures from both spectroscopic and time-resolved vacuum Rabi measurements.Comment: revised version: improved analysis, 4 pages, 4 figures, hi-res version available at http://qudev.ethz.ch/content/science/PubsPapers.htm

    Phase-Coherent Dynamics of a Superconducting Flux Qubit with Capacitive-Bias Readout

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    We present a systematic study of the phase-coherent dynamics of a superconducting three-Josephson-junction flux qubit. The qubit state is detected with the integrated-pulse method, which is a variant of the pulsed switching DC SQUID method. In this scheme the DC SQUID bias current pulse is applied via a capacitor instead of a resistor, giving rise to a narrow band-pass instead of a pure low-pass filter configuration of the electromagnetic environment. Measuring one and the same qubit with both setups allows a direct comparison. With the capacitive method about four times faster switching pulses and an increased visibility are achieved. Furthermore, the deliberate engineering of the electromagnetic environment, which minimizes the noise due to the bias circuit, is facilitated. Right at the degeneracy point the qubit coherence is limited by energy relaxation. We find two main noise contributions. White noise is limiting the energy relaxation and contributing to the dephasing far from the degeneracy point. 1/f-noise is the dominant source of dephasing in the direct vicinity of the optimal point. The influence of 1/f-noise is also supported by non-random beatings in the Ramsey and spin echo decay traces. Numeric simulations of a coupled qubit-oscillator system indicate that these beatings are due to the resonant interaction of the qubit with at least one point-like fluctuator, coupled especially strongly to the qubit.Comment: Minor changes. 21 pages, 15 figure
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