Tele-education Process Modelling supported by the ODP Enterprise Viewpoint Language

This paper reports on applying the ODP enterprise viewpoint in the domain of tele-education. The work is conducted as part of a research activity that aims at designing a tele-education system to support planning, execution and evaluation of dynamic distributed educational processes. We explore the ODP enterprise viewpoint as a basis for communication and co-operation between educational scientists and ODP systems designers involved in the design process. Our application of the enterprise viewpoint involves four main steps. First, an educational language is proposed to describe educational processes in generic terms. Second, a set of appropriate enterprise language concepts is selected. Third, a relationship is established between the educational language and enterprise language concepts. Fourth, an educational process is modelled in terms of an entity-oriented model and a behaviour-oriented model. It is hoped that the experience gained in this exercise will provide useful feedback to both the educational and ODP communitie

Clinical foundations and information architecture for the implementation of a federated health record service

Clinical care increasingly requires healthcare professionals to access patient record information that may be distributed across multiple sites, held in a variety of paper and electronic formats, and represented as mixtures of narrative, structured, coded and multi-media entries. A longitudinal person-centred electronic health record (EHR) is a much-anticipated solution to this problem, but its realisation is proving to be a long and complex journey. This Thesis explores the history and evolution of clinical information systems, and establishes a set of clinical and ethico-legal requirements for a generic EHR server. A federation approach (FHR) to harmonising distributed heterogeneous electronic clinical databases is advocated as the basis for meeting these requirements. A set of information models and middleware services, needed to implement a Federated Health Record server, are then described, thereby supporting access by clinical applications to a distributed set of feeder systems holding patient record information. The overall information architecture thus defined provides a generic means of combining such feeder system data to create a virtual electronic health record. Active collaboration in a wide range of clinical contexts, across the whole of Europe, has been central to the evolution of the approach taken. A federated health record server based on this architecture has been implemented by the author and colleagues and deployed in a live clinical environment in the Department of Cardiovascular Medicine at the Whittington Hospital in North London. This implementation experience has fed back into the conceptual development of the approach and has provided "proof-of-concept" verification of its completeness and practical utility. This research has benefited from collaboration with a wide range of healthcare sites, informatics organisations and industry across Europe though several EU Health Telematics projects: GEHR, Synapses, EHCR-SupA, SynEx, Medicate and 6WINIT. The information models published here have been placed in the public domain and have substantially contributed to two generations of CEN health informatics standards, including CEN TC/251 ENV 13606

On the design of application protocols

In the last decades, much effort has been spent on the design and provision of sophisticated communication infrastructures. The development of end-user oriented distributed system applications, leaning on top of these communication infrastructures, so far has attracted little attention. This is regrettable, since communication infrastructures can only become useful and profitable if they can be deployed in the context of a sufficient number of distributed applications.\ud Two important factors determine the success of distributed applications: (1) the provision of high quality application services and protocols at short time scales; and (2) the availability of standards for these services and protocols that can be used for the construction of �open� distributed systems. The achievement of both (1) and (2) can be supported by a suitable design methodology.\ud A design methodology entails a systematic approach to carry out complex designs, and therefore should incorporate proper concepts that enable the effective structuring of such designs. Concepts currently used for the design and structuring of application protocols appear to be inadequate for this purpose. Also a step-wise design approach that would help to master complexity and shorten development times is currently lacking.\ud Standards are necessary since individual users of distributed system applications prefer to be independent on any particular manufacturer or vendor when procuring products, while manufacturers prefer to have maximum implementation freedom when developing such products. An �open� protocol standard defines necessary and sufficient conditions for system parts to interact, such that the system parts can be implemented independently of each other.\ud ISO and ITU-TSS base the development and definition of protocol standards on a �reference model�, called the Reference Model for Open Systems Interconnection (OSIRM). This model comprises a rudimentary form of a design approach and a reference architecture that can be derived with this approach. According to the OSI-RM, the overall application protocol functionality is distributed over three hierarchical protocol layers. Each layer has been assigned a specific functionality, except the highest layer, the Application\ud Layer, which is made responsible for all remaining protocol functions. Because the functionality of the Application Layer is not delimited it cannot, as opposed to the other layers, be covered by a single protocol standard or a fixed set of protocol standards. Several identified sets of Application Layer protocol functions are defined by separate Application Service Elements (ASEs).\ud The appropriateness of the OSI-RM for the development and definition of application protocol standards can be criticized on a number of points:\ud - the reference architecture defined by the OSI-RM is not flexible enough to adequately cope with the diversity of interaction requirements of distributed applications.\ud - some design concepts are not clearly defined, thus prohibiting their effective application to structuring problems;\ud - the relationship between high level application requirements and proposed application protocol solutions is unclear;\ud - the development of application protocol standards generally takes a long time.\ud This thesis aims at the development of a methodology for the design of application protocols, including application protocol standards, and so addresses the problems mentioned above. The following contributions are made to achieve this aim:\ud - design quality criteria are proposed that can be used to guide design decisions and to evaluate designs;\ud - OSI design decisions and design concepts with respect to application protocols are evaluated;\ud - general-purpose, elementary design concepts are proposed;\ud - milestones in the application protocol design process are presented;\ud - behaviour composition and structuring techniques are developed that can be used to represent design results corresponding to the identified milestones;\ud - design methods are proposed to support the correct performance of design steps between milestones;\ud - a flexible reference architecture is proposed.\ud A (potential) result of the design methodology is that layered application protocol hierarchies can be avoided if they are not required by the class of distributed applications that must be supported

Interim research assessment 2003-2005 - Computer Science

This report primarily serves as a source of information for the 2007 Interim Research Assessment Committee for Computer Science at the three technical universities in the Netherlands. The report also provides information for others interested in our research activities

Managing healthcare transformation towards P5 medicine (Published in Frontiers in Medicine)

Health and social care systems around the world are facing radical organizational, methodological and technological paradigm changes to meet the requirements for improving quality and safety of care as well as efficiency and efficacy of care processes. In this they’re trying to manage the challenges of ongoing demographic changes towards aging, multi-diseased societies, development of human resources, a health and social services consumerism, medical and biomedical progress, and exploding costs for health-related R&D as well as health services delivery. Furthermore, they intend to achieve sustainability of global health systems by transforming them towards intelligent, adaptive and proactive systems focusing on health and wellness with optimized quality and safety outcomes. The outcome is a transformed health and wellness ecosystem combining the approaches of translational medicine, 5P medicine (personalized, preventive, predictive, participative precision medicine) and digital health towards ubiquitous personalized health services realized independent of time and location. It considers individual health status, conditions, genetic and genomic dispositions in personal social, occupational, environmental and behavioural context, thus turning health and social care from reactive to proactive. This requires the advancement communication and cooperation among the business actors from different domains (disciplines) with different methodologies, terminologies/ontologies, education, skills and experiences from data level (data sharing) to concept/knowledge level (knowledge sharing). The challenge here is the understanding and the formal as well as consistent representation of the world of sciences and practices, i.e. of multidisciplinary and dynamic systems in variable context, for enabling mapping between the different disciplines, methodologies, perspectives, intentions, languages, etc. Based on a framework for dynamically, use-case-specifically and context aware representing multi-domain ecosystems including their development process, systems, models and artefacts can be consistently represented, harmonized and integrated. The response to that problem is the formal representation of health and social care ecosystems through an system-oriented, architecture-centric, ontology-based and policy-driven model and framework, addressing all domains and development process views contributing to the system and context in question. Accordingly, this Research Topic would like to address this change towards 5P medicine. Specifically, areas of interest include, but are not limited: • A multidisciplinary approach to the transformation of health and social systems • Success factors for sustainable P5 ecosystems • AI and robotics in transformed health ecosystems • Transformed health ecosystems challenges for security, privacy and trust • Modelling digital health systems • Ethical challenges of personalized digital health • Knowledge representation and management of transformed health ecosystems Table of Contents: 04 Editorial: Managing healthcare transformation towards P5 medicine Bernd Blobel and Dipak Kalra 06 Transformation of Health and Social Care Systems—An Interdisciplinary Approach Toward a Foundational Architecture Bernd Blobel, Frank Oemig, Pekka Ruotsalainen and Diego M. Lopez 26 Transformed Health Ecosystems—Challenges for Security, Privacy, and Trust Pekka Ruotsalainen and Bernd Blobel 36 Success Factors for Scaling Up the Adoption of Digital Therapeutics Towards the Realization of P5 Medicine Alexandra Prodan, Lucas Deimel, Johannes Ahlqvist, Strahil Birov, Rainer Thiel, Meeri Toivanen, Zoi Kolitsi and Dipak Kalra 49 EU-Funded Telemedicine Projects – Assessment of, and Lessons Learned From, in the Light of the SARS-CoV-2 Pandemic Laura Paleari, Virginia Malini, Gabriella Paoli, Stefano Scillieri, Claudia Bighin, Bernd Blobel and Mauro Giacomini 60 A Review of Artificial Intelligence and Robotics in Transformed Health Ecosystems Kerstin Denecke and Claude R. Baudoin 73 Modeling digital health systems to foster interoperability Frank Oemig and Bernd Blobel 89 Challenges and solutions for transforming health ecosystems in low- and middle-income countries through artificial intelligence Diego M. López, Carolina Rico-Olarte, Bernd Blobel and Carol Hullin 111 Linguistic and ontological challenges of multiple domains contributing to transformed health ecosystems Markus Kreuzthaler, Mathias Brochhausen, Cilia Zayas, Bernd Blobel and Stefan Schulz 126 The ethical challenges of personalized digital health Els Maeckelberghe, Kinga Zdunek, Sara Marceglia, Bobbie Farsides and Michael Rigb

A framework for abstracting complexities in service delivery platforms

The telecommunication (telco) and Information Technology (IT) industries are converging into a single highly competitive market, where service diversity is the critical success factor. To provide diverse services, the telco network operator must evolve the traditional voice service centric network into a generic service centric network. An appropriate, but incomplete, architecture for this purpose is the Service Delivery Platform (SDP). The SDP represents an IT-based system that simplifies access to telco capabilities using services. SDP services offer technology independent interfaces to external entities. The SDP has vendor-specific interpretations that mix standards-based and proprietary interfaces to satisfy specific requirements. In addition, SDP architectural representations are technology-specific. To be widely adopted the SDP must provide standardised interfaces. This work contributes toward SDP standardisation by defining a technology independent and extendable architecture, called the SDP Framework. To define the framework we first describe telecom-IT convergence and a strategy to manage infrastructure integration. Second, we provide background on the SDP and its current limitations. Third, we treat the SDP as a complex system and determine a viewpoint methodology to define its framework. Fourth, we apply viewpoints by extracting concepts and abstractions from various standard-based telecom and IT technologies: the Intelligent Network (IN), Telecommunication Information Networking Architecture (TINA), Parlay, enhanced Telecommunications Operations Map (eTOM), Service Oriented Architecture (SOA) and Internet Protocol Multimedia Subsystem (IMS). Fifth, by extending the concepts and abstractions we define the SDP framework. The framework is based on a generic business model and reference model. The business model shows relationships between SDP, telco and external entities using business relationships points. The reference model extends the business model by formalising relationships as reference points. Reference points expand into interfaces exposed by services. Applications orchestrate service functions via their interfaces. Service and application distribution is abstracted by middleware that operates across business model domains. Services, interfaces, applications and middleware are managed in Generic Service Oriented Architectures (GSOA). Multiple layered GSOAs structure the SDP framework. Last, we implement the SDP framework using standard-based technologies with open service interfaces. The implementation proves framework concepts, promotes SDP standardisation and identifies research areas

Literature review

There are many studies that reveal the nature of design thinking and the nature of conceptual design as distinct from detailed or embodiment design. The results can assist in our understanding of how the process of design can be supported and how new technologies can be introduced into the workplace. Existing studies provide limited information about the nature of collaborative design as it takes place on the ground and in the actual working context. How to provide appropriate and effective of support for collaborative design information sharing across companies, countries and heterogeneous computer systems is a key issue. As data are passed between designers and the computer systems they employ, many exchanges are made. These exchanges may be used to establish measures of the benefits that new support systems can bring. Collaboration support tools represent a fast growing section of the commercial software market place and a reasonable range of products are available. Many of them offer significant application to design for the support of distributed meetings by the provision of video and audio communications and the sharing of information, including collaborative sketching. The tools that specifically support 3D models and other very design specific features are less common and many of those are in prototype stages of development. A key question is to find viable ways of combining design information visualisation support with the collaboration support technologies that can be seen today. When collaborating, different views will need to be accessible at different times to all the collaborators. The architects may want to explain some ideas on their model, the structural engineers on their model and so on. However, there are issues of ownership when the structural engineer wants to manipulate the architect’s model and vice versa. The modes of working, synchronous or asynchronous may have a bearing as in a synchronous session there is control of what is happening